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    Hemoglobin cooperativity and adaptations to high altitude living
    This resource accompanies the "How does blood carry oxygen?" chapter in the Integrating Concepts in Biology etext. Students evaluate the cooperativity of hemoglobin and adaptations to high...

    Keywords: Integrating Concepts in Biology

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    Using Podcasts as a Supplemental Learning Tool for Genetics
    Genetics is a fascinating topic of biology. Establishing relevance is a key component of student learning. To increase learning, this resource includes summaries and teaching guides for integrating...

    Keywords: geneticspodcasts

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    Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts
    Lesson on what it means for biological processes to be Poissonian, published in CourseSource

    Keywords: quantitative biologybioinformaticsmicrobiologyphysicsNIBLSEHIVCourseSourcemultiplicity of infectionPoisson Distribution

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    Instructor Guide: Integrating Project Leadership, Artificial Intelligence, Simulation and Google Tools to Understand Regulation of Gene Expression with the Lac Operon and Lactase Gene
    Scientific leadership and current artificial intelligence (AI) skills are important skills to be included in the course curriculum. Together or individually, these skills can enhance knowledge,...

    Keywords: Resources @ HHMI - BioInteractivebiologymolecular biologygenomicsArtificial Intelligencegene expressionleadershipgroup worklactosegoogle toolsSeniorPhET SimulationLactase

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    A Hands-on Introduction to Hidden Markov Models
    A lesson in which students will understand the basic structure of an HMM, the types of data used in ab initio gene prediction, and its consequent limitations.

    Keywords: Markov modelbioinformaticsgenomicsNIBLSEtranscriptionCourseSourceexonintronsplicing

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    Teaching RNAseq at Undergraduate Institutions: A tutorial and R package from the Genome Consortium for Active Teaching
    This lesson plan was created to teach RNAseq analysis as a part of GCAT-SEEK network. It is provided here, both in finished form and with the modifiable source code, to allow flexible adaptation to...

    Keywords: statisticsR programming languagebioinformaticsNIBLSERNAseqgene expressionCourseSourcecomputer programming

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    Plasmodium Problem Space
    This problem space brings together diverse resources with the goal of helping biology teachers and learners engage in research investigations.

    Keywords: bioinformaticsproblem spacesNIBLSERNAseqmalariaplasmodium

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    Linking Intermediate Disturbance Hypothesis to Traditional Ecological Knowledge and Conservation
    Traditional Ecological Knowledge is based on deep understanding of systems from observations made over hundreds to thousands of years. This resource connects Traditional Ecological Knowledge to...

    Keywords: climate changeenvironmental justiceintermediate disturbance hypothesisTraditional ecological knowledge

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    Finding Selection in All the Right Places
    Lab introducing students to evolutionary genetics using bioinformatics and biocuration, published as GSA Learning Resource

    Keywords: geneticsbioinformaticssequencingNIBLSE

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    BSL-4: Authorized Personnel Only
    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

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    Introductory Video and worksheets on Module 1 and 2 on "Sequence Similarity: An inquiry based and under the hood..."
    The video walks the students to complete Module 1 and 2 on Sequence Similarly and Alignment adapted from Tapprich (2019) and Hudson Alpha that teaches these modules within the context of the...

    Keywords: bioinformaticssequencingFASTANCBINIBLSEalgorithmsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixCourseSource

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    Genotype-phenotype associations: What are they, and how are they related to broader society?
    In this lesson, students will explore contexts in which a single genotype does not directly yield a single phenotype (polygenic traits and gene x environment interactions). Students will reflect on...

    Keywords: journal clubevolution educationInclusive teachinggenotype to phenotypeGenotype-Phenotype Connectionspolygenic traitsgenotype x environment interactions

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    Why Cells Change Weight: Demonstrating Linear Regression Through an Osmosis Experiment
    In this activity, students will perform an experiment utilizing dialysis tubing to create cellular models to demonstrate the linear relationship between cell weight and time in varying tonicities....

    Keywords: graphingqbccCellular and Molecular BiologyInterpret graphsConcepts in Statistics

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    Learn Biological Sciences and Mathematics through cellular respiration, photosynthesis and primary productivity.
    Photosynthesis is a process by which plants synthesize glucose and oxygen in presence of sunlight through light dependent reactions by utilization of sunlight, water to synthesize oxygen, ATP and...

    Keywords: mathematicssimulationThe Analysis of Biological DataMetabolic Pathwaysprocess of sciencephotosynthesisqbccBiological ScienceshypothesisCellular Respirationprimary productivity

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    Teaching logistic population growth and ecological modelling
    The lesson is designed to 1) teach students about the concept of logistic population growth, growth rates, and carrying capacity and 2) provide a basic introduction to ecological modeling and...
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    Using Regression Models to Examine the Effect of Carbon Dioxide on Fluid pH
    In this activity students will use statistics and regression models to explore the effects of carbon dioxide on blood pH by measuring pH changes that occur over time as carbon dioxide reacts with...

    Keywords: BiochemistryphysiologyAnatomyGeneral BiologyChoosing modelsCreate graphsInterpret graphsConcepts in Statisticscreate modelsmake predictions

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    Learn biotechnology, biophysics and business through scientific thinking and innovation
    Scientific, leadership and innovation skills are also an integral framework of the curriculum. All of them together or individually are important for enhancement of knowledge, critical thinking,...

    Keywords: educationbusinessBiotechnologybiophysicsleadershiprecombinant DNAgroup workcloninginnovationscientific thinkingplasmid

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    Human Evolution for Secondary and College Students
    This module is made up of four concepts. The goal of the first concept is to elicit an understanding of primate relatedness, phylogeny, and how specific characteristics are beneficial for life in...

    Keywords: fossilsprimatesevolutionary biologyhominin evolutionhuman biologyGeneral Biology

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    Building creatures with the central dogma of biology
    Activity that demonstrates how nucleotide changes can affect phenotypes

    Keywords: amino acidsnucleotidesRNADNAgenotypephenotypecentral dogma

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    Kinetics of a Highly Conserved Enzyme - Carbonic Anhydrase
    This module contains exercises designed to introduce students to graphical representation of biological data. Students will explore the fundamental principles of enzyme kinetics including...

    Keywords: Excelintroductory biologycell biologygraphingslopeQuantitative reasoningdata visualizationquantitative biologyinterdisciplaryquantitative skillscorrelationenzyme functionInterpreting GraphsMichaelis-Mentenenzyme kineticsEnzyme activityenzyme inhibitionLinear and nonlinear analysisNIQBC2. Data and GraphsC4. mathematical modelsenzyme-substrateNIQB Interdisciplinary Quantitative Reasoningcarbonic anhydrase

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