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Sequence Similarity Resource Adaptation: Exploring Ebola Virus

This adaptation of the sequence similarity resource provides biology students with a basic set of bioinformatics concepts and tools. These concepts and tools are used to explore relationships...

Keywords: phylogeneticsbioinformaticsEbolasequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogram

2058

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5307

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comments

adaptations

Introductory Video and worksheets on Module 1 and 2 on "Sequence Similarity: An inquiry based and under the hood..."

The video walks the students to complete Module 1 and 2 on Sequence Similarly and Alignment adapted from Tapprich (2019) and Hudson Alpha that teaches these modules within the context of the...

Keywords: bioinformaticssequencingFASTANCBINIBLSEalgorithmsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixCourseSource

1148

views

1279

downloads

comments

adaptations

COVID-19: Molecular Basis of Infection-ADAPTATION

This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

1213

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1635

downloads

comments

adaptations

Drugging SARS-CoV-2

This case study leads students through the process of proposing a drug for a novel protein. The Mpro protease of SARS-CoV-2 is explored in detail within the PDB. Aligns with first semester...

Keywords: viruscoronavirusPDBSARS-CoV-2proteasedrug design

1256

views

358

downloads

comments

adaptations

Investigating Evidence for Climate Change (Project EDDIE)

This multi-part activity allows students to discover the relationships between CO2 and temperature and how these variables have changed over time using real-world data.

Keywords: Excelclimate changeGlobal Temperature Changeco2ice core data

1481

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817

downloads

comments

adaptations

Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

4581

views

809

downloads

comments

adaptations

Statistics with epidemiology of COVID-19

Introduction into heat maps, non-parametric t-test and GIF (optional) in R using an original dataset on COVID-19 infections from different counties of New Jersey, USA. Suitable for students who...

Keywords: Rundergraduate educationheat mapsCOVID19coronavirusSARS-CoV-2GIF

1491

views

510

downloads

comments

adaptations

Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?

Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

views

117

downloads

comments

adaptations

Introduction to nucleotide sequence analysis and protein modeling in MEGA and PyMol using coronavirus SARS-CoV-2

Introduction into computational approaches in phylogeny and protein modeling based on coronavirus SARS-CoV-2 (caused COVID-19 pandemic). Two self-guided tutorials for standard lab classes of 2.5...

Keywords: phylogeneticsundergraduate educationbioinformaticsNCBICOVID19coronavirusMEGAPyMolvirtual labPDBprotein modelingSARSSARS-CoV

1148

views

576

downloads

comments

adaptations

Open. Adaptable. Free.

Resources created by our members and partners.

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Sequence Similarity Resource Adaptation: Exploring Ebola Virus

Introductory Video and worksheets on Module 1 and 2 on "Sequence Similarity: An inquiry based and under the hood..."

COVID-19: Molecular Basis of Infection-ADAPTATION

Drugging SARS-CoV-2

Investigating Evidence for Climate Change (Project EDDIE)

Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

Statistics with epidemiology of COVID-19

Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?

Introduction to nucleotide sequence analysis and protein modeling in MEGA and PyMol using coronavirus SARS-CoV-2

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