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    Tag You're It: A Lesson Investigating Study Design and Survival Analysis on an American Shad Tagging Study
    In this lesson, students will learn about the various mark-recapture and tagging methods that are used in various scientific disciplines and the information they can gather. Key elements of...

    Keywords: survival analysisAmerican ShadCox Proportional Hazards ModelStudy Design

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    Calling Bull Case Study — 99.9% Caffeine-free with R
    This is an adaptation of Calling Bull's Case Study on how caffeine free is hot chocolate versus coffee in order to make it into a student project that uses R.

    Keywords: Rcase studyRStudiointroductionPercentagescalling bullstoichiometrycaffienescripts

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    Drugging SARS-CoV-2
    This case study leads students through the process of proposing a drug for a novel protein. The Mpro protease of SARS-CoV-2 is explored in detail within the PDB. Aligns with first semester...

    Keywords: viruscoronavirusPDBSARS-CoV-2proteasedrug design

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    Seed Dispersal in Tropical Forests
    In this activity, students use data from published studies to understand patterns of seed dispersal and apply these ideas to the design of a conservation area.

    Keywords: ecologyResources @ HHMI - BioInteractivecommunityplantsdiversityScientific Process

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    Exaggerated Traits and Breeding Success in Widowbirds
    Teaching Notes on the Exaggerated Traits and Breeding Success in Widowbirds

    Keywords: Evolutionexperimental designsexual dimorphismsexual selectionNatural SelectionWidowbirdsbirdintrasexual selectionintersexual selectionhandicap hypothesis

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    A Curious Display
    Case study on genetically modified organisms provided in English and American Sign Language.

    Keywords: geneticscase studyagricultureBiotechnologyenvironmental scienceDNAUniversal Design for LearningGMOAmerican Sign Language

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    My Twin Sister Case Study
    A young boy wonders why his twin sister can roll his tongue, but he cannot. Case centers on meiosis.

    Keywords: case studymeiosistwins

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    HITS: A Network to Create Inquiry-based Case Studies | BIOME 2022
    We created the NSF-funded High-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students (HITS) Research Coordination Network to address this gap. HITS brings together...

    Keywords: case studiesHigh-throughput Discovery Science & Inquiry-based Case Studies for Today’s StudentsHigh-throughput (HT) approaches

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    Case Study — World records as measures of senescence or randomness
    This is a project meant to accompany the Case Study that Carl Bergstrom, which uses R to explore whether declining track and field world record performance could be an artifact of sample size (less...

    Keywords: RRStudioprogrammingsampling distributionProbability & Statisticsrandomnesscontinuous probability distribution

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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    Teaching Protein Structure Modeling
    New strains of microbes have been regularly discovered and brought into a laboratory for study in many different directions. When a new microbial genome is sequenced and assembled, the homologues...

    Keywords: Microbiology Educationbioinformaticsprotein structure modeling

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    Selection and the Blond Beach Mouse
    National Center for Case Study Teaching in Science- this "clicker" case study explores ultimate and proximate explanations for cryptic coloration in animals.
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    Coyote Habituation and a Scientist Spotlight on Dr. Christopher Schell
    Dr. Christopher Schell is an ecologist who uses a variety of techniques to study mammalian carnivores in urban areas. This scientist spotlight uses graphs from his study on parental habituation to...

    Keywords: conservation ecologyanimal behaviorurban ecologyInterpreting GraphsBLACK SCIENTISTS IN STEMcoyotes

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    Seed Dispersal in Tropical Forests - implementation at a small, Primarily Undergraduate Institution
    In this activity, students use data from published studies to understand patterns of seed dispersal and apply these ideas to the design of a conservation area.

    Keywords: ecologyResources @ HHMI - BioInteractivecommunityplantsdiversityScientific Process

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    Seed Dispersal in Tropical Forests
    In this activity, students use data from published studies to understand patterns of seed dispersal and apply these ideas to the design of a conservation area. This was applied through the lens of...

    Keywords: ecologyResources @ HHMI - BioInteractivecommunityplantsdiversityScientific Process

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    Predator-Prey Interactions: Selective foraging by wolf spiders
    This interactive case study is intended for use in lower-division biology or ecology courses to complement the SimUText (SimBio) chapter entitled Predation, Herbivory and Parasitism.
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    Leaf litter and soil invertebrates
    The diversity of invertebrates occupying the leaf litter and organic layer of soil can be quantified to examine abiotic and biotic questions. This lab can be used as a starting point for a...
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    Calculating Lifetime Cancer Risk Resulting from DNA Replication
    An expanded case study adapted from an HHMI Data Point on Cell Division and Cancer Risk using Figure 1 from Tomasetti, C. and Vogelstein, B. (2015).

    Keywords: cancerScientific ProcessStatistics and MathScientific Methodologybiology of cellscell growth and divisionHigh School

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    Exploring Coyote Morphology: Introduction to Research and Study Design
    This module is designed as a first foray for freshman-level (novice undergraduate) students into science literacy, research design, and use of museum resources in research activities. The module...

    Keywords: statisticsnatural history museumsdistance learningscience literacyStudy Designintraspecific variation

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    BSL-4: Authorized Personnel Only
    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

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