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    Bioinformatics / Neuroinformatics
    This module is a computer-based introduction to bioinformatics resources.  This easy-to-adopt module weaves together several important bioinformatic tools so students can grasp how each is used in...

    Keywords: bioinformaticsNIBLSEImageJquantitative trait locusQTL

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    DNA Subway Learning Resources
    DNA Subway is a NIBLSE Recommended resource. This is a collection of learning resources associated with DNA Subway.

    Keywords: phylogeneticsIntroductoryLabbioinformaticsUndergraduateNIBLSEDNA BarcodingDNA sequenceBLASTmultiple sequence alignmentDNA SubwayInstructional SettingAudience LevelAdvancedActivity LengthExtended ProjectC1. Role of bioinformaticsC2. Computational conceptsC4. Bioinformatics toolsC5. Data retrievalC8. Data types

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    Bioinformatics: the Power of Computers in Biology – a Practical Guide
    This Practical Guide in the Bringing Bioinformatics into the Classroom series introduces simple bioinformatics approaches for database searching and sequence analysis.

    Keywords: NIBLSEGOBLET

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    Murder by HIV? Undergraduate edition
    Bioinformatics case study focusing on phylogenetic tree interpretation, published in the National Center for Case Study Teaching in Science

    Keywords: case studyResources @ NSF - NCCSTSbioinformaticsNIBLSEHIVnucleotide sequencingphylogenetic treeviral life cyclesmutation ratesreverse transcriptase sequences

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    Sequence Similarity: A Quick Introduction to Bioconductor
    Following the Sequence Similarity exercises by Kleinschmit, et al., this tutorial will guide students in using the Bioconductor suite of R packages to likewise compute sequence similarity.

    Keywords: bioinformaticssequencingNIBLSEmultiple sequence alignmentsequence similarityBLOSUM scoring matrixBioconductor

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    Bioinformatics: An Interactive Introduction to NCBI
    Modules showing how the NCBI database classifies and organizes information on DNA sequences, evolutionary relationships, and scientific publications. And a module working to identify a nucleotide...

    Keywords: NCBINIBLSEDNABLASTnucleotide sequencing

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    Yeti or not: Do they exist?
    Through this 4-part bioinformatics case study, students will be led through the forensic analysis of putative Yeti artifacts based on published findings.

    Keywords: case studybioinformaticsNIBLSEBLAST12S sequencingYeti

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    Genome Solver: Complete Set of Lessons
    The Genome Solver Project began as a way to teach faculty some basic skills in bioinformatics - no coding or scripting. These Lessons also work well in the undergraduate classroom, culminating...

    Keywords: bioinformaticsNIBLSEBioinformatics EducationBioinformatics and GenomicsC4. Bioinformatics toolsC5. Data retrievalC6. ModelsC8. Data typesC9. ImplicationsRecommended by NIBLSE

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    Sequence Similarity: Introducing Biological Databases to Community College Biology Students
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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    Developing a phylogram from computational resources.
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsBLASTmultiple sequence alignmentsequence similarityneighbor-joining distance matrixCourseSourcephylogrampercent identity matrix

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    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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    Colon Cancer: A Case of Genetic Bad Luck
    Case study developed for an introductory genetics class published in the National Center for Case Study Teaching in Science

    Keywords: bioinformaticsNCBINIBLSEBLASTPublished in National Center for Case Study Teaching in Sciencecolon cancerpedigreegenetic testingAPC

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    Finding Selection in All the Right Places
    Lab introducing students to evolutionary genetics using bioinformatics and biocuration, published as GSA Learning Resource

    Keywords: geneticsbioinformaticssequencingNIBLSE

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    Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
    In this four- part guided activity, students will learn about the structure and function of human autosomal and sex chromosomes, view and interpret gene maps, and gain familiarity with basic...

    Keywords: bioinformaticsNIBLSECourseSourceautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

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    Inquiry-based hypothesis testing using phylogenetic trees in MEGA
    A key learning objective in biology is applying bioinformatics tools to test a real-life question. These inquiry-based modules have students assemble and align data, and construct simple...

    Keywords: phylogeneticsbioinformaticsFASTANCBIBLASTmultiple sequence alignmentsequence similarityCourseSourceZika virusMEGAalcohol metabolism

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    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    In this lesson, we describe an easily adaptable lab module that can be used in existing undergraduate molecular biology lab courses to conduct authentic scientific research, published in CourseSource

    Keywords: molecular biologybioinformaticsNIBLSEgene regulationmicroRNAsgene expressionCourseSourcemiRNA

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    The Ames Test
    Introduction to the Ames Test, published as GSA Learning Resource

    Keywords: geneticsNIBLSEDNAames testassay

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    Exploring HIV Evolution
    In this activity you will study aspects of sequence evolution by working with a set of HIV sequence data from 15 different subjects (Markham, et al., 1998). You will first learn about the dataset,...

    Keywords: EvolutionbioinformaticssequencingUndergraduateNIBLSEincubatorsHIVAudience LevelC1. Role of bioinformaticsC4. Bioinformatics toolsRecommended by NIBLSE

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    BSL-4: Authorized Personnel Only
    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

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    Introductory Video and worksheets on Module 1 and 2 on "Sequence Similarity: An inquiry based and under the hood..."
    The video walks the students to complete Module 1 and 2 on Sequence Similarly and Alignment adapted from Tapprich (2019) and Hudson Alpha that teaches these modules within the context of the...

    Keywords: bioinformaticssequencingFASTANCBINIBLSEalgorithmsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixCourseSource

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