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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    An introduction to population matrix models: a swirl lesson
    Students will learn how to set up a population matrix model in R and use it for demographic analysis of a population, including projecting population growth, determining lambda and the stable age...

    Keywords: population dynamicsRpopulation growthonlinedemographypopulation projection modelquantitative biologypopulation modelmatrix modelspopulation ecologyage structurepopulation biologypopulation modelingSwirlDemographic processespopulationLeslie matrix

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    Why does Blood Flow Change? Investigating the Math of Blood Flow Dynamics
    This collection of activities explores the relationship between blood flow, pressure, and the factors of resistance through graphs and modeling direct and inverse variation.

    Keywords: quant biographingRatiosmathassessmentcollege algebraundergraduate educationphysiologyAnatomyhuman biologyvariationCardiovascular physiologyAnatomy & Physiologylab activityOpenStaxqbccmanipulate equationsUnderstanding fractionsChoosing modelsUnderstanding ratesEstimating answersUse elementary functionsCreate graphsInterpret graphsRates and ProportionsSolving Equations and Inequalities

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    Materials for Teaching the SIR Epidemic Model
    This web page contains materials created by faculty of the University of Nebraska-Lincoln Department of Mathematics to teach basic fundamentals of mathematical epidemiology.
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    A Case of Severe Insulin Resistance
    This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistance

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    Caribbean coral reef structure and biodiversity - Comparing boosted regression tree & multiple regression approaches
    Creating and comparing boosted regression tree models to multiple regression models.
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    NELF Explorer: Drivers of Landscape Change
    Students explore the connections between land use decisions and land cover change, as well as how to predict the possible impacts of land use decisions into the future.

    Keywords: landscape ecologyscenario analysisland systems scienceLULCC

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    Global Temperature Change in the 21st Century: An Introduction to Global Climate Models and Graphing in Excel (Adapted for Non-Majors)
    Students link human behavior in various climate change scenarios to predicted temperature outcomes at both local (their assigned Latitude) and global (Latitudinal trends) scales. This adaptation is...

    Keywords: ExcelResources @ ESA - TIEEecology labclimate changeenvironmental scienceglobal changehuman-environmental interactionsSimple Linear Regressionhuman impactsinclusive pedagogy-FMN

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    Antigen presentation and cytotoxic T lymphocytes (CTLs): elucidating a common roadblock for students
    Active learning resource for pre-Nursing anatomy and physiology lecture explaining antigen presentation to CTLs and how the CTLs recognize and destroy the pathogen using Biointeractive animations...

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

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    A Tough Choice in Watershed Management
    In this Team-based activity, students work in teams, playing the role of natural resource managers who must decide in which region to invest limited funding for nutrient reduction in streams....

    Keywords: Stream ecologyBox PlotsSpreadsheetGroup cooperative learningTeam-based LearningBiogeochemical cycles

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    Sickle Cell Disease Case Study
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    Conducting Analysis of Variance (ANOVA) in R with swirl
    This lesson offers an introduction to ANOVA, including 1) how this statistical test can be differentiated from others and 2) a step-by-step guide to conducting and interpreting ANOVA results in R,...

    Keywords: biostatisticsR programming languageSwirl

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    Sickle Cell Disease and Natural Selection in Humans
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    Island Biogeography
    The students will practice the basic code to test MacArthur and Wilson’s (1967) Island Biogeography model, focusing on how island size, distance, and perturbation affect species numbers.
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    Data Analysis and Cancer
    This is a flipped classroom approach, students will learn the basic content about cell-signaling, p53, and transcription factors before class. During class students will focus on data analysis...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologydata interpretationBiological Data Analysiscell cyclemacromoleculesGenetic diseaseCell signaling

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    Bacteria Transformation
    TeachEngineering resource in which students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria.

    Keywords: bacteriaengineeringGMOsbacterial transformationplasmids

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    Lake Mixing Module (Project EDDIE)
    Students explore spatial and temporal patterns of lake mixing using high-frequency temperature data from lakes around the world.

    Keywords: stratificationProject EDDIE

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    Cross-Scale Interactions (Project EDDIE)
    Students explore new modeling and computing tools while learning fundamental concepts about how lake phytoplankton blooms occur through cross-scale interactions.

    Keywords: modelingProject EDDIE

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    Climate Change Effects on Lake Temperatures (Project EDDIE)
    Students explore new modeling and computing tools while learning fundamental concepts about how climate change will affect lakes

    Keywords: climate changeProject EDDIElakes

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    Altruism Simulation Activity
    An altruism activity that uses a NetLogo altruism simulation.

    Keywords: Evolutiontool:netlogoanimal behavioraltruism

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