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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    The Evolution of Human Skin Color
    My teaching notes for the Evolution of Human Skin Color case study.

    Keywords: EvolutionNatural SelectionSkin pigmentationskin colorvitamin Dvitamin B folateultraviolet lightUV light

    1164

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    400

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    adaptations

    Mol* Adaptation: Case of Severe Insulin Resistance
    This is an adaptation using Mol* on the original case written. This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to...

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistanceMol*MolStar

    849

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    148

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    0

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    BSL-4: Authorized Personnel Only
    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

    1119

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    206

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

    1130

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    468

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    0

    adaptations

    A Case of Severe Insulin Resistance
    This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistance

    1350

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    530

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    0

    comments

    1

    adaptations

    Evolution of Caffeine Biosynthesis Enzymes
    This case focuses on exploring why plants make secondary metabolites like caffeine and how the enzymes required for making caffeine evolved.

    Keywords: Evolutioncaffeinemolecular visualization and analysisenzymesPDBMolecular Case Study

    1311

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    528

    downloads

    0

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

    1562

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    496

    downloads

    0

    comments

    4

    adaptations

    COVID-19: Molecular Basis of Infection
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

    1906

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    639

    downloads

    0

    comments

    2

    adaptations

    Maria vs Malaria
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria.

    Keywords: bioinformaticsmolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

    387

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    249

    downloads

    0

    comments

    1

    adaptations

    Colon Cancer: A Case of Genetic Bad Luck
    Case study developed for an introductory genetics class published in the National Center for Case Study Teaching in Science

    Keywords: bioinformaticsNCBINIBLSEBLASTPublished in National Center for Case Study Teaching in Sciencecolon cancerpedigreegenetic testingAPC

    388

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    71

    downloads

    0

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    0

    adaptations

    Selection and the Blond Beach Mouse
    National Center for Case Study Teaching in Science- this "clicker" case study explores ultimate and proximate explanations for cryptic coloration in animals.
    959

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    211

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    0

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    adaptations

    How Many More Thymes? A Case of Phytochemical Defense
    National Center for Case Study Teaching in Science- this clicker case addresses several concepts related to the evolutionary ecology of herbivore defenses.

    Keywords: food websgenotypephenotypeHerbivoryherbivoredeterrencemonoterpeneproducerchemotypeThymus vulgaristhymeMediterranean ecosystemchemical defenses

    1032

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    186

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    0

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    1

    adaptations

    Managing Prairie Dogs for Ferret Reintroduction
    This case study explores the ecological relationship between black-tailed prairie dogs and black-footed ferrets.

    Keywords: case studysocio-environmental data

    1469

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    243

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    0

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    2

    adaptations

    Waking up Anna - Adaptations and Conversion to Mol*
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment. The adaptations addressed question clarity and reformatting to use Mol*.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABAMolCaseNetMol*MolStarProtein visualizationFlumazenil

    903

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    1413

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    0

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    adaptations

    Waking up Anna
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABA

    1298

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    499

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    0

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    1

    adaptations

    Climate Diagrams Mini-Case Study for Ecology
    This mini-case study provides undergraduate ecology students with experience in how to read climate diagrams and how to put them together. The activity includes a discussion of actual and potential...
    1027

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    723

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    0

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    0

    adaptations

    Maria vs Malaria - AR Adaptation
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria. Students will be able to view selected molecular views from the...

    Keywords: bioinformaticsAugmented RealityLarge class sizemolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

    331

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    184

    downloads

    0

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    Using Case Studies to Engage Students in Wicked Problems
    Interactive presentation on using case studies at the 2018 QUBES/BioQUEST Summer Workshop

    Keywords: case studiesSummer Workshop 2018wicked problems

    1388

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    993

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    Sea Turtles- A Case Study
    The case study on sea turtles will allow students to think about field work and examine graphs to understand data. It will provide experience for non-majors environmental science classes to think...
    4030

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    2097

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    Doctor in the House: Improving Undergraduate Critical Thinking Skills Through Diagnosing Medical Case Studies
    Students in undergraduate anatomy and physiology courses are not often exposed to clinical examples of homeostatic imbalances, particularly ones that provide an opportunity to diagnose a...

    Keywords: medicinediagnosiscardiovasculardeductive reasoningdigestiveEndocrinehomeostatic imbalancehypothetico-deductive modelurinary

    1432

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    476

    downloads

    0

    comments

    0

    adaptations

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