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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Investigating Cell Signaling with Gene Expression Datasets
    Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing...

    Keywords: genomicstranscriptionsignaling

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    DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.
    Advances in high-throughput techniques have resulted in a rising demand for scientists with basic bioinformatics skills as well as workshops and curricula that teach students bioinformatics...

    Keywords: geneticsbioinformaticsDNAgenotypephenotypegenegene annotation

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    Tree Biomass and Phenology
    This lesson centers around understanding the connection of tree biomass and phenology with climate change. It uses both swirl and LearnR lessons in the R programming language to help students make...
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    Understanding Gene Prediction Programs
    Introduces students to the key biological concepts underlying computational gene prediction. Outcomes include ability to analyze and evaluate output of gene prediction programs, and reflect on...

    Keywords: Genome annotationSEA-PHAGESgene predictiongenemarkcoding potentialcodon biassix frame translation

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    An Interactive Protocol for In-Classroom DNA Extraction
    Using commonly available materials, this tool allows students to extract DNA, exploring DNA chemistry and the principles of experimental design and execution. We take a “Choose Your Own...

    Keywords: geneticsDNAbiochemical structure and function

    1945

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    Analysis of Microbiomes Using Free Web-Based Tools in Online and In-Person Undergraduate Science Courses
    Our understanding of microbiomes, or the collection of microorganisms and their genes in a given environment, has been revolutionized by technological and computational advances. However, many...

    Keywords: microbiomeDNA SubwayCyVerseCourse based undergraduate researchQIIME2ranacapa

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    Backward Design with Digital Data
    Best practices for designing educational modules using biodiversity data

    Keywords: data in the classroombackward designbiodiversity collections

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    QUBES – A virtual synthesis center catalyzing change in undergraduate quantitative biology education
    Presentation about QUBES given at HHMI Constellation Meeting: Advancing science students mastery of quantitative skills.

    Keywords: quantitative biology education

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    Predicting and classifying effects of insertion and deletion mutations on protein coding regions
    Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...

    Keywords: mutationcentral dogmatranslationframeshift

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    How to Find a Gene: Retrieving Information From Gene Databases
    A strong understanding of distinct gene components and the ability to retrieve relevant information from gene databases are necessary to answer a diverse set of biological questions. However, often...

    Keywords: NCBItranscriptiontranslationGene StructureGene databasesEnsembl

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    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness...

    Keywords: prokaryotesgene regulationLac Operoninducible operon

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    Basic Statistics
    The students will practice identifying the appropriate basic statistical tests when given a scenario and learn how to run and interpret those statistical tests in R.
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    Exploring the population dynamics of wintering bald eagles through long-term data using R
    The purpose of this modification was to take the analyses that were done in Excel and have the students perform them using R. Students were not given any R code for this activity, as R code was...

    Keywords: Resources @ ESA - TIEEcase studyR programming languagepopulation ecologyendangered speciesconservation biologymigration ecologyggplot2

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    Teaching logistic population growth and ecological modelling
    The lesson is designed to 1) teach students about the concept of logistic population growth, growth rates, and carrying capacity and 2) provide a basic introduction to ecological modeling and...
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    Data simulation and randomization tests
    A participatory live-coding lesson on simulating data and performing randomization tests on ecological data in R.
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    Laboratory exercises on microbial growth, horizontal gene transfer, competition and evolution
    Simple laboratory exercises to reinforce student learning when performed in conjunction with NetLogo simulations.

    Keywords: microbiology

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    Sample NetLogo Code of Bacterial Growth
    Each NetLogo file is a sequential version of the final bacterial growth model produced in the Bacterial Growth Tutorial. These are to be used as checks to one's understanding alongside the tutorial.
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    Using DNA Subway to Analyze Sequence Relationships
    This is a bioinformatics exercise using the DNA Subway Blue Line, a user-friendly pipeline of bioinformatics tools, to analyze a collection of mosquito DNA bar-code sequences.

    Keywords: phylogeneticsNIBLSEDNA BarcodingDNA sequenceBLASTmultiple sequence alignmentC1. Role of bioinformaticsC2. Computational conceptsC4. Bioinformatics toolsC5. Data retrievalC8. Data typesIncubated at NIBLSE

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    Go Extinct! An Award-Winning Evolution Game That Teaches Tree-Thinking as Students Pursue the Winning Strategy
    Evolutionary trees communicate both the diversity and unity of life, a central and important scientific concept, as highlighted by the Vision and Change undergraduate biology education movement....

    Keywords: phylogeneticsnatural historyBiodiversitycladogramCommon ancestorEvolutionary treeLand vertebratesMonophyletic cladeTetrapods

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    Converting a Face-to-Face Lab to Online: An Example of Process and Outcomes for a CRISPR-Based Molecular Biology Lab
    The COVID-19 pandemic created a need to convert in-person laboratory courses into an online format in a short amount of time. For this reason, we converted our face-to-face molecular biology lab...

    Keywords: mutationtranscriptioncrisprtranslation

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