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    Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation
    Success in biochemistry and other life science courses requires that students understand important biological concepts. One of these concepts is how gene regulation ensures that homeostasis is...

    Keywords: gene regulationinducible operonProkaryotic cellPhosphoenolpyruvate transferase system (PTS)

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    A CURE-based approach to teaching genomics using mitochondrial genomes
    There is an abundance (currently over 1016 DNA bases) of publicly available genetic sequence data and a dearth of trained genomicists to process and interpret it, necessitating more trained...

    Keywords: proteinsMitochondrial GenomesNuclear GenomesrRNAtRNA

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    Marriage Model (with errors)
    Marriage age model for use with NetLogo and ABM material

    Keywords: computational modelagent-based modelsocial networksmarriageChapter 6Chapter 6.5

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    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how...

    Keywords: pathwayscancerMolecular AlterationsRetrospective dataTumorigenesis

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    Healing the scars: Tropical rainforest carbon cycling. Does it matter which tree species you plant?
    This online module explores how differences in traits of tropical tree species translate into differential effects on the carbon cycle, integrating ecological information across scales and the...

    Keywords: climate changecarbon cyclingtropical biology4DEE Frameworkforest restorationtropical tree speciessoil carbon

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    2008-Yang-EtAl-Differential Equation Model of HIV Infection of CD T-Cells with Delay 
    Abstract: An epidemic model of HIV infection of CD4+ T-cells with cure rate and delay is studied. We include a baseline ODE version of the model, and a differential-delay model with a discrete time...

    Keywords: virusT cellsHopf bifurcationendemic equilibrium

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    An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure
    Gene structure, transcription, translation, and alternative splicing are challenging concepts for many undergraduates studying biology. These topics are typically covered in a traditional lecture...

    Keywords: bioinformaticsGenome BrowsergenomicsRNAseqsplicingComputer ModelGene Structure

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    Web Popgen
    A Hardy-Weinberg simulation program.

    Keywords: Hardy-Weinbergpopulation geneticscomputer simulationsGenetic DriftmutationNatural Selection

    2050

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    Data Analysis for the Life Sciences
    An online stats book written completely in R

    Keywords: Rbiostatisticsstatistical analysisR Markdown

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    Thinking deeply about quantitative analysis: Building a Biologist's Toolkit
    Vision and Change in Undergraduate Biology Education encouraged faculty to focus on core concepts and competencies in undergraduate curriculum. We created a sophomore-level course, Biologists'...

    Keywords: Vision and ChangeRRStudioquantitative literacystatistical analysisScientific communication

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    Towards better modelling and decision support: Documenting model development, testing, and analysis using TRACE
    We introduce TRACE, a framework for documenting model testing and analysis. TRACE is based on the recently proposed framework of model "evaluation" , and is designed to make models fit for...

    Keywords: standardizationgood modelling practicerisk assessmentdecision supportTRACEResources @ QUBES - Teaching & Reference

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    2006-Graves-Peckham-Pastor-2D differential equations model for mutualism
    We develop from basic principles a two-species differential equations model which exhibits mutualistic population interactions.

    Keywords: population dynamicsLotka-Volterragrowth ratemutualismLichen

    206

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    Wolf Sheep Predation Simulation Exercise
    This resource is an exercise to introduce students to agent-based modeling of biological systems through working with a simple existing model.

    Keywords: simulationecologyIntroductoryNetLogoagent-based modelingagent-based modelLabbioinformaticspredator-preyUndergraduateNIBLSEInstructional SettingAudience LevelActivity LengthLess than 1 hoursimulation cycleC1. Role of bioinformaticsC6. ModelsReviewed at NIBLSEagent based modleing

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    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.

    Keywords: compartment modelpharmacokineticsnonlinear estimationone compartment model

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    2018-Hu-Huang-Dynamic Regulation Responding to an External Stimulus
    This study examines the dynamic regulation process responding to an external stimulus. This study introduces the driven damped oscillator model which has an additional parameter to identify...

    Keywords: dynamical systemsregulationsteady statesales modelexternal stimulus

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    2010-Kijek-Kijek-Modelling of Innovation Diffusion
    This paper offers a first order differential equation model for innovation diffusion, solves it, and offers qualitative analysis as well as approaches to estimating parameters with some data on...

    Keywords: Bass modelinnovation diffusionLogistic modeldynamic model

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    Exploration of the Human Genome by Investigation of Personalized SNPs
    Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To...

    Keywords: UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

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    2020-Stepien_Kostelich_Kuang-Mathematics Cancer An Undergraduate Bridge Course in Applied Mathematics
    Most undergraduates have limited experience with mathematical modeling. This paper describes a course on the mathematical models of cancer growth and treatment.

    Keywords: differential equationsmodelingundergraduate educationcancertumor

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    Pharmacokinetics
    This Excel module explores how drugs are processed and absorbed in the human body.

    Keywords: drug metabolismpharmacokinetics

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    2014-Vance-Eads-Sensitivity Analysis of a Three-Species Nonlinear Response Omnivory Model with Predator Stage Structure
    We investigate a three-species nonlinear response omnivory model incorporating stage structure in the top predator. The model consists of four coupled ordinary differential equations involving...

    Keywords: stage structuresensitivity analysismortalityomnivoreomnivory modelsearch rates

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