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    A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation
    Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is...

    Keywords: mutationProtein Structureethicscentral dogmahuman disease

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    A Hands-on Introduction to Hidden Markov Models
    In this Lesson, we describe a classroom activity that demonstrates how a Hidden Markov Model (HMM) is applied to predict a eukaryotic gene, focusing on predicting one exon-intron boundary. This HMM...

    Keywords: transcriptionexonintronsplicing

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    A CRISPR/Cas Guide RNA Design In Silico Activity
    CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become...

    Keywords: bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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    2017-Sim-EtAl-Optimal control of a coupled tanks system with model-reality differences
    In this paper, an efficient computational approach is proposed to optimize and control a coupled tanks system.

    Keywords: optimal controlflowtankscoupled tanks

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    1-136-MarriageAge-ModelingScenario
    Students will build and analyze a model of the fraction of people who are married (for the first time) by a certain age. Students are asked to set up and solve these differential equations. They...

    Keywords: messagesmarriageusing social sciences in forecastingdirected

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    A Pipeline in Paradise, Part 1: Learning the Relevant Science
    This case requires students to integrate information across the following five “knowledge domains” to develop a baseline understanding of the problem.

    Keywords: case studysocio-environmental data

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    Investigating Sexually Transmitted Disease (STD) Ecologies Using Geographic Information Systems (GIS) (Abstract) | TIEE
    Identifying, mapping and understanding the magnitude and the spatial prevalence of the Sexually Transmitted Diseases (STDs) such as chlamydia and gonorrhea diseases. Analyzing the spatial trends of...

    Keywords: Resources @ ESA - TIEEDisease ecologyfmnDIGhuman ecology and behaviorbacterial infectionsspatial and temporal spread of diseaseGeographic Information System (GIS)

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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression.  This laboratory lesson allows students...

    Keywords: bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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    SCIENCE/Fiction: Modular Template for Class Design
    We present a modular scaffold for designing an introductory seminar using speculative fiction and science papers to welcome university undergraduates to the biology major. A list of twelve possible...

    Keywords: geneticscell biologyneurosciencesystems biologyScience Fiction

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    BioQUEST Webinar: CourseSource - YouTube
    Follow the link to the webinar video, "An Introduction to the CourseSource Journal and Making Your Own Collections". This webinar provides an overview of CourseSource, how to publish your teaching...
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    Venom: To Kill or Cure?
    In this case study, students will explore concepts of evolution, protein structure and function, taxonomy, and methods of scientific inquiry in a real-world way.

    Keywords: EvolutionphylogeneticsidigbioAP Biologytaxonomynatural history collections3D modelsoVertVenomsnakesherps

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    Examining the Physiology Behind the Symptoms of Lactose Intolerance
    This is a set of extension questions for the HHMI short film The Making of the Fittest: Got Lactase? The Co-evolution of Genes Video Activity.
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    Diseasebots HEXBUG Lab
    This module explores the effects of host density on contact rates and transmission of pathogens using a hands-on experiment with HEXBUG robots.
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    The Evolution of Human Skin Color
    My teaching notes for the Evolution of Human Skin Color case study.

    Keywords: EvolutionNatural SelectionSkin pigmentationskin colorvitamin Dvitamin B folateultraviolet lightUV light

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    Mendelian Genetics, Probability, Pedigree, and Chi-Squared Statistics
    A lesson that requires students to work through a series of questions pertaining to the genetics of sickle cell disease and its relationship to malaria.

    Keywords: geneticsResources @ HHMI - BioInteractiveScientific ProcessStatistics and Mathmendelian inheritance

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    Allele and Phenotype Frequencies in Rock Pocket Mouse Populations
    A lesson that uses real rock pocket mouse data collected by Dr. Michael Nachman and his colleagues to illustrate the Hardy-Weinberg principle.

    Keywords: EvolutionResources @ HHMI - BioInteractiveNatural SelectionScientific ProcessStatistics and Mathevolution of populations

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    Exploring Indigenous Viewpoints in the Undergraduate Biology Classroom: An Environmental Case Study Incorporating Hawaiian Traditional Ecological Knowledge
    Changing science education to foster greater equity and inclusion for Indigenous students will require effort from instructors and institutions. Instructors can help by including Traditional...

    Keywords: ecologycase studyenvironmentsystems thinkingTraditional ecological knowledgeindigenous knowledgehawai'idecolonizing scienceNative knowledgeFish ponds

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    Investigating human impacts on stream ecology: locally and nationally
    This module is a modification of the Nuding and Hampton module in TIEE Volume 8. This modified module includes data from Alaska and is modified to be completed as an asynchronous lab in an online...

    Keywords: aquatic macroinvertebratesAlaskaStream ecologynutrient pollutionHuman Impacts of Ecosystemsecological monitoringasynchronous learning

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    Interconnections in The Open Ecosystem
    Presentation on open education and open science given as the keynote address at the 2019 BioQUEST & QUBES Summer Workshop

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Do urban yards serve as a refuge for native land snail species?
    This module contains a series of take-home activities to prepare students to analyze their own dataset collected in lab.

    Keywords: urban ecosystemsrefugia from habitat lossJMP

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