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    Maria vs Malaria
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria.

    Keywords: bioinformaticsmolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    Immunity and Vaccine Action
    From the cellular level on up, being aware of your interactions can help you stay safe. This resource addresses fundamental immunology and infectious disease concepts through a historical...

    Keywords: immunology educationvaccine literacyvaccine hesitancy

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    2018-Meredith_Greer-Ella_Livesay-Mathematical Epidemiology Goes to College
    In this article we present models that were inspired by two real-life outbreaks at a small residential college campus: H1N1 influenza in 2009 and, surprisingly, mumps in 2016.

    Keywords: epidemiologydiseaseH1N1Influenzaoutbreak

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    2018-Joseph-EtAl-A Nonlinear differential equation model of Asthma effect of environmental pollution using LHAM
    In this paper, we investigated a nonlinear differential equation mathematical model to study the spread of asthma in the environmental pollutants from industry and mainly from tobacco smoke from...

    Keywords: asthmatobacco smokeLiao’s Homotopy analysis Method (environmental pollutants

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    2015-Joshi-EtAl-Optimal control of an SIR model with changing behavior through an education campaign
    We study stability analysis and use optimal control theory on the system of differential equations to achieve the goal of minimizing the infected population (while minimizing the cost).

    Keywords: SIR modelsvaccinepopulationwater treatmentsusceptibleeducation campaignminimizing costinfected

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    2014-Allen-EtAl-Perturbations in Epidemiological Models -When zombies attack we can survive
    In this paper, we investigate the existence of stability-changing bifurcations in epidemiological models used to study the spread of zombiism through a human population.

    Keywords: epidemiologydynamical systemszombiesbifurcationperturbation

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    When tests disagree, how do I know if I have COVID-19?
    Students will learn about infectious disease and the immune response to infection by investigating different types of tests (PCR, antigen, and antibody tests) to detect the SARS-CoV-2 viral genetic...

    Keywords: geneticsVision and Changeintroductory biologyinfectious diseasemolecular biologycore competenciesRT-PCRviruscore conceptsnon-majors biologySARS-CoV-2antibodyAntigenImmunoReachmolecular DiagnosticsCOVID-19 transmission

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    A discussion on SARS-CoV-2 wastewater surveillance efforts with Amanda Cauble
    In this episode of LWS, we had Amanda Cauble, an associate engineer at Central San. She discusses what Central San is and the methods of surveilling SARS-CoV-2 in wastewater. This talk was recorded...

    Keywords: disease surveillanceSARS-CoV-2wastewater

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    1-070-FisheryHarvest-ModelingScenario
    Students model with logistic growth, harvesting, and diffusion in analyzing ocean fisheries of the Atlantic cod. We help students build models, ever more complex, to capture physical realities. At...

    Keywords: logisticDiffusionmanagementharvestfishery

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    6-018-ExploringSIRModel-ModelingScenario
    Students will transform, solve, and interpret Susceptible Infected Recovered (SIR) models using systems of differential equation models. The project is progressively divided into three parts to...

    Keywords: population dynamicssensitivitydiseaseSIR modelsepidemicrumors

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    Hemoglobin bioinformatics
    This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief...

    Keywords: bioinformaticsHemoglobinBLASTsickle cell diseaseMolecular Case StudyClustal OmegaMolCaseNet

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    Using Bioinformatics to Understand Genetic Diseases: A Practical Guide
    This Practical Guide outlines a number of basic bioinformatics approaches that can be used to understand the molecular basis of genetic diseases.
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    SEIR simulation activity for flattening the curve
    This is a short exploration activity to introduce SIR and SEIR models without explicitly introducing differential equations. It utilizes the R package EpiDynamics and students can run the...

    Keywords: RRStudioInfectious Disease ModelingSIR modelsSIRseircovidcoronavirus

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    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

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    Drug screening and cancer resistance: EGFR Activity
    This activity explores a specific gene (egfr) and its role in cancer. EGFR was introduced with the Gene Card Activities, researched throughout the semester, and then authentic image data of...

    Keywords: Resources @ HHMI - BioInteractivegenomicscancergenetic basis of diseasebiology of cells

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    Robot vs. Disease: Using CellProfiler to model biomedical research in your classroom
    Resource from the 2015 BioQUEST Summer Workshop

    Keywords: image analysisCellProfilerfluorescence microscopymicroscopycellular analysis

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    A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics
    Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need...

    Keywords: epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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    Leslie/Lefkovitch Matrix Models for Age or Stage-structured Populations
    This Excel workbook uses the Leslie matrix model for population projection of age-class structured populations, and also allows Lefkovitch matrix models for stage-class structured populations.

    Keywords: survivalpopulation ecologyfecundityLeslie matrixeigenvalueseigenvectorsLefkovitch matrixage-class structured populationsstage-class structured populationsreproductive value

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    Implementing an online module about tropical seed dispersal and restoration in an undergraduate ecology course in the Pacific Northwest, USA
    This “Spreading Seeds” case study introduces students to ecology of seed dispersal mutualisms, and their importance for forest restoration. The implementation plan teaching notes, and associated...

    Keywords: mutualismRestoration Ecologyspecies interactionHabitat fragmentationSeed dispersalforest recovery

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    How to Create a Pollinator Project on iNaturalist
    Community science, also known as citizen science, allows any person to participate in scientific research. It breaks down the traditional barriers between scientists and the public, allowing anyone...

    Keywords: Plant EcologyPlant-insect interactions#iNaturalistpollinatorsCitizen and Community Sciencepollination ecology

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