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    Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms
    Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell...

    Keywords: mutationcancertranscriptioncell cycletranslationOncogenesTumor-suppressorp53Transcription factor

    1955

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    Integrating Manipulatives and Animations to Visualize Holliday Junctions
    The complex molecular architecture of Holliday junctions is often challenging for undergraduate biochemistry students to conceptualize. In particular, they have difficulty translating from...

    Keywords: dna structureDNA damageDNA recombinationGene crossoverHolliday junction

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    Sizes, Scales and Specialization: Adapted to add scientific notation review
    This module explores how cell size and shape varies across cell types in the human body by having students calculate relative proportions of numbers in scientific notation. The adaptation has...

    Keywords: ExponentsRatiosScientific Notationcell typeqbccmanipulate equationsCellular and Molecular Biologyconverting unitschanging scales

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    Sizes, Scales and Specialization: Using Relative Proportions and Scientific Notation to Highlight the Diversity of Cell Types
    This module explores how cell size and shape varies across cell types in the human body by having students calculate relative proportions of numbers in scientific notation.

    Keywords: ExponentsRatiosCellsqbccmanipulate equationsCellular and Molecular BiologyVisual Accommodationsconverting unitschanging scales

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    Biological Cellular Automata Laboratory (BioCA Lab)
    This Excel module includes both linear cellular automata and 2D cellular automata. The original 3 rules for survival, death, and birth are implemented in this module, but users with some Excel...

    Keywords: cellular automata

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    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    Introductory bioinformatics exercises often walk students through the use of computational tools, but often provide little understanding of what a computational tool does "under the...

    Keywords: BLASTmultiple sequence alignmentsequence similarityphylogramZika virusAlgorithmScoring Matrix

    1918

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    635

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    Biology from Molecules to Embryos, Interactive Animated Lessons
    Visualizing kinetic processes can be an impediment to student mastery of basic science coursework. To remedy this obstacle, I created an educational program called Biology from Molecules to...

    Keywords: geneticsBIOMEEmbryologycomputer assisted instructioneducational programeducational videosonline lessonsanimated lessonseducational website

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    2014-John_Cimbala-Dynamic System Response
    In this learning module, we discuss the dynamic system response of sensors and their associated electronic circuits.

    Keywords: sensor networksoscillationssystem responseelectronic circuit

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    Fragile States: A Case Study Exploring Genetics, Molecular Biology, and Biochemistry Through the Lens of Fragile X Syndrome
    This case aims to strengthen students’ understanding of molecular biology concepts through study of Fragile X Syndrome (FXS). Students begin by learning the cause and phenotypes of FXS and...

    Keywords: gene regulationtranscriptiontranslationFragile X syndrometriplet repeat expansionsex linkagemetabolic pathway

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    A Close-Up Look at PCR
    The Polymerase Chain Reaction (PCR) is a fundamental laboratory technique that allows for the amplification of many copies of a desired DNA target sequence. Despite its prevalence, undergraduate...

    Keywords: PCRDNA replication

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    From Dirt to Streptomyces DNA
    The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular...

    Keywords: MetabolismAntibiotic productionrRNA genesSecondary metabolitesStreptomyces

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    An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure
    Gene structure, transcription, translation, and alternative splicing are challenging concepts for many undergraduates studying biology. These topics are typically covered in a traditional lecture...

    Keywords: bioinformaticsGenome BrowsergenomicsRNAseqsplicingComputer ModelGene Structure

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    Teaching Cell Structures through Games
    As the basic unit of life, cells are a foundational concept for all of biology. Before students can appreciate how eukaryotic cells function either in isolation or in higher order and multicellular...

    Keywords: Cell Structurecell organellesTransmembrane Transport

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    Collaborative case writing and field testing with Molecular CaseNet brings together discipline specific expertise for innovative pedagogical tools in the classroom
    Molecular case studies (MCS) use an interesting story as a hook , followed by exploration of biochemistry of one or more molecules of interest.  They can be useful in teaching about macromolecule...
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    2018-Hu-Huang-Dynamic Regulation Responding to an External Stimulus
    This study examines the dynamic regulation process responding to an external stimulus. This study introduces the driven damped oscillator model which has an additional parameter to identify...

    Keywords: dynamical systemsregulationsteady statesales modelexternal stimulus

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    Why Cells Change Weight: Demonstrating Linear Regression Through an Osmosis Experiment
    In this activity, students will perform an experiment utilizing dialysis tubing to create cellular models to demonstrate the linear relationship between cell weight and time in varying tonicities....

    Keywords: graphingqbccCellular and Molecular BiologyInterpret graphsConcepts in Statistics

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    From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design
    Engaging first generation underrepresented minority students in the process of inquiry in developmental biology is important to increase diversity in future graduate STEM education. One important...

    Keywords: experimental designC. elegansCre/LoxPFate mapheart developmentheart regenerationmousereporter constructzebrafish

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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs...

    Keywords: fluorescence microscopymitosisCell StructureCell ImagingImmunocytochemistryQuantitative microscopySTEM skills

    1945

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    502

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    Green Design: How do Leaf Structures Optimize Photosynthesis and Promote Survival?
    One of the major learning objectives established by the American Society of Plant Biologists and the Botanical Society of America has students answer the question: How do plant structures enable...

    Keywords: photosynthesisepidermal layerleaf anatomymesophyllpalisade parenchymaplant anatomyplant structure functionspongy parenchymaStomata

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    Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter
    While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division...

    Keywords: DiffusionActive transportfacilitated diffusionNecessary and sufficientTransport proteins

    1965

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    468

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