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    Exploring Fundamental Concepts of Phage Immunity Systems: A jigsaw activity
    This jigsaw assignment is designed to increase students’ understanding of phage immunity systems
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    Modeling Soil Fluxes with NEON Data
    This activity is an exploratory activity to understand rates of change of soil carbon dioxide in different ecosystems using data provided by the National Ecological Observatory Network (NEON,...

    Keywords: modelingdata analysisplant/soil/water interactions

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    Data Analysis and Cancer
    This is a flipped classroom approach, students will learn the basic content about cell-signaling, p53, and transcription factors before class. During class students will focus on data analysis...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologydata interpretationBiological Data Analysiscell cyclemacromoleculesGenetic diseaseCell signaling

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    A Fun Introductory Command Line Exercise: Next Generation Sequencing Quality Analysis with Emoji!
    This resource is a fun computer-based intro to command line programming. The activity takes FASTQ NGS data files and runs a fun program called FASTQE.

    Keywords: data sciencebioinformaticsnext generation sequencingquality controlFASTQgenomicsprogrammingNIBLSElinuxmicrobiomeIllumina sequencingcommand lineFASTQEFASTPNGS analysisterminalMacemojiPhred scoreTrimmingshort read

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    Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts
    Lesson on what it means for biological processes to be Poissonian, published in CourseSource

    Keywords: quantitative biologybioinformaticsmicrobiologyphysicsNIBLSEHIVCourseSourcemultiplicity of infectionPoisson Distribution

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    More In Depth Spreadsheet Management Adaptation of Data Management using NEON Small Mammal Data
    This adaptation consists of three exercises that introduce students to 1) format spreadsheet data tables, 2) carry out spreadsheet quality control, and 3) count/sort/filter data of interest in...

    Keywords: data managementspreadsheetsmammalsCapture mark-recapture

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    Mapping Coral Bleaching Modified with NOAA and Authentic Bleaching data
    Students access NOAA data to conduct an analysis to look at differences between locations in heat stress and ultimately the amount of coral bleaching in 2005

    Keywords: ecologyBiodiversityclimateScientific ProcessStatistics and Mathecosystemsearth and environmenthuman impacts

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    Investigating Gene Expression and Cell Specialization in Axolotl Embryos
    The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most...

    Keywords: developmenttranscriptiongene expressionmodel organismembryo

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    Simulating Cortical Rotation, Axis Induction, and Experimental Embryology in Amphibian Embryos Using Clay Models
    The study of development requires learners to understand spatially complex concepts like embryo anatomy. Embryo anatomy is dynamic over time, and it is often manipulated by researchers in...

    Keywords: developmentXenopusfertilizationEmbryologyinductionSymmetry breakingOrganizerCortical rotationPatterning

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    A Lesson on Matter and Energy at the Organismal Scale: Linking Patterns and Processes Across Diverse Taxa
    Pathways and transformations of energy and matter (PTEM) are a conceptually challenging but essential component of biological literacy. Curricular gaps about PTEM nevertheless remain; although...

    Keywords: plantsenergyAnimalsfungimatterorganismal scale

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    Climate Change Connections
    This module is composed of three related activities that introduce students to climate change's complexity from a conceptual standpoint. In the first activity, students work in small groups to...

    Keywords: interdisciplinaryclimate changeconcept mapping

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    Cladistic Analysis Lesson Using Bats
    Phylogenetic analysis can be a challenging concept to grasp for undergraduate biology students. This cladistic analysis lesson utilizes the amazingly diverse Order Chiroptera as a model to...

    Keywords: batsphylogeny and classificationVertebrate Morphologycladistic analysisbat evolution

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    Why does Blood Flow Change? Investigating the Math of Blood Flow Dynamics
    This collection of activities explores the relationship between blood flow, pressure, and the factors of resistance through graphs and modeling direct and inverse variation.

    Keywords: quant biographingRatiosmathassessmentcollege algebraundergraduate educationphysiologyAnatomyhuman biologyvariationCardiovascular physiologyAnatomy & Physiologylab activityOpenStaxqbccmanipulate equationsUnderstanding fractionsChoosing modelsUnderstanding ratesEstimating answersUse elementary functionsCreate graphsInterpret graphsRates and ProportionsSolving Equations and Inequalities

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    Bioinformatics: Investigating Sequence Similarity - A Plant Biology Approach
    This laboratory module is a modification of the original published on CourseSource with a focus on plant biology. In the final activity, students conduct a BLAST to compare histone protein...

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBIplant biologyNIBLSEalgorithmsincubatorsPlant and Fungal EvolutionBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogram

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    Examining human impacts on tusk evolution in elephants using authentic research data
    In this activity students explore and analyze real, authentic research data paired with HHMI’s “Selection for Tuskless Elephants” video in a hands-on investigation of human impacts on elephant...
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    Escape Zoom!: Reviewing Introductory Evolution Content Using an Escape Room Format
    Reviewing and integrating key concepts and learning goals at the end of a biology course can be overwhelming to students and instructors alike. Often end-of-term review sessions in preparation for...

    Keywords: Evolutionartificial selectionSpeciationextinctionsexual selectionphylogenetic treesmechanisms of evolution

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    Temperature Balance Equation Activity
    Students learn about the temperature balance equation. They then conduct a thought experiment (with a worksheet) using the components of the equation to manage their heat balance for survival on a...

    Keywords: equationtemperatureheatevaporationconductionconvectionMetabolicRadiation

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    Strategic Planning for REU and Research Readiness
    Students complete a personal strategic plan, examining their strengths, vision and mission for completing an REU or research experience.

    Keywords: undergraduate researchREUstrategic planningSWOTresumepersonal statement

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    Climate Change Module (Project EDDIE): Instructor Implementation
    This details an implementation of the climate change module, where students explore how climate is using data. Produced by Project EDDIE.
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    Exploring Health Inequities and Redlining
    For this assignment, students will investigate relationships between historic redlining data and modern statistics of human health.

    Keywords: diseasehealthsocial justicepublic healthData science for Biologistredliningchronic diseasesocial vulnerability

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