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    Investigating Gene Expression and Cell Specialization in Axolotl Embryos
    The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most...

    Keywords: developmenttranscriptiongene expressionmodel organismembryo

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    Evolution Through Natural Selection
    This Excel workbook simulates the population genetics of a single gene with two alleles, allowing the user to set the initial allele frequencies and enter parameters for a variety of different...

    Keywords: population geneticsNatural Selection

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    Module 1: Introduction to the Genome Browser: What is a Gene?
    This lesson introduces the University of California Santa Cruz genome browser to students, walking them through some of the key features so that it can be used for analysis of gene structure.

    Keywords: geneticsbioinformaticsGenome BrowserSimilarity searchesExonsIntronsEvidence TrackStart CodonStop Codon

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    Sickle Cell Anemia using Nicholas’ Story
    The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...

    Keywords: Hemoglobinsickle cell diseaseMolecular Case Study

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    Mentoring Undergraduate Research Projects in Mathematical Biology
    Part of the 2015 SMB Minisymposium: Topics in Biomathematics Education

    Keywords: epidemiologymentoringcurriculumundergraduate researchGene regulatory networkpest management

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    Bioinformatics: Food Detective – a Practical Guide
    This Practical Guide in the Bringing Bioinformatics into the Classroom series introduces the idea of computers as tools to help understand aspects of biology.
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    An Introduction to Biodiversity Databases and Specimen Images
    In this module, students will be introduced to some biodiversity data resources and how to search for and download herbarium specimen images. They will be asked to think critically about the...

    Keywords: data in the classroombiodiversity informaticsnatural history collection

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    GSEAtheory
    Brief introduction to how gene set enrichment analysis works.

    Keywords: videosbioinformaticsgenomicsyoutubegsea

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    Module 2: Transcription Part I: From DNA Sequence to Transcription Unit
    This module illustrates how a primary transcript (pre-mRNA) is synthesized using a DNA molecule as the template. Students will learn about the importance of the 5' and 3' regions of the gene for...

    Keywords: data visualizationmolecular biologybioinformaticsGenome BrowsergenomicsTranscription InitiationTranscription Start SiteTranscription Termination Signal

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    RNA-seq Analysis
    In this computer lab module, students learn how to process an RNA-seq data set to identify differentially expressed genes (DEGs). The samples for this data set were collected from yeast cells...

    Keywords: LabRNAsequencingUndergraduateNIBLSEincubatorsRNAseqInstructional SettingAudience LevelActivity LengthMore than 1 hourC4. Bioinformatics toolsC5. Data retrievalReviewed at NIBLSEdifferentially expressed genes

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    A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics
    Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need...

    Keywords: epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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    You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”
    With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented...

    Keywords: bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently...

    Keywords: modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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    Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners
    Manipulating gene expression is a commonly used tool to study the effect of a single gene or the hierarchy of gene networks in many different biological disciplines. When working with mice, the...

    Keywords: mathematical modelhomologous recombinationCre/loxgene targeting

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    The Case of the Missing Strawberries: RFLP analysis
    While solving the fictional mystery of the missing strawberries, students are engaged in a guided-inquiry lesson featuring small-group and class discussions, hands-on activities, and laboratory...

    Keywords: process of scienceDNAforensicsgel electrophoresisMolecular genotypingRestriction endonucleaseRestriction enzymeRestriction fragment length polymorphismRFLP

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    An Introduction to Eukaryotic Genome Analysis in Non-model Species for Undergraduates: A tutorial from the Genome Consortium for Active Teaching
    Advances in Next Generation Sequencing (NGS) technology have led to development of many research methods for analyzing genomic data. Students studying biology at the undergraduate level must hone...

    Keywords: Speciationgenome evolutiongenetic variation

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    Sequence Similarity: Introducing Biological Databases to Community College Biology Students
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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    A 360˚ View of COVID-19
    In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new...

    Keywords: geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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    GBIF Tutorial - BLUE Resource
    A user guide and video instructions for GBIF

    Keywords: Querying databasesdatabasedata in the classroombiodiversity informaticsbiodiversity collections

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    Arctos Tutorial - BLUE Resource
    A user guide and video instructions for Arctos

    Keywords: databasesdata in the classroombiodiversity informaticsbiodiversity collections

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