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    2008-Ribbing-EtAl-Mathematical models of diabetes progression
    Writing a good model for diabetes progression is difficult because the long time span of the disease makes experimental verification of modeling hypotheses extremely awkward. underlying the

    Keywords: physiologyclinical trialsdiabetesdiabetes progression

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    2007-Ramsay-Hooker-Campbell-Cao-Parameter estimation for differential equations-a generalized smoothing approach
    We propose a new method for estimating parameters in models that are defined by a system of non-linear differential equations.

    Keywords: estimating equationfunctional data analysisGauss–Newton methodparameter cascadeprofiled estimationdynamic system

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    2002-Patrick_Nelson-Alan_Perelson-Mathematical_analysis_of_delay_differential _equation_models_of_HIV-1_infection
    Models of HIV-1 infection that include intracellular delays are more accurate representations of the biology and change the estimated values of kinetic parameters when compared to models without...

    Keywords: delayHIV-1T cellscombination antiviral therapy

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    1-009-Bifurcation-TechniqueNarrative
    We lead students to investigate first-order differential equations that contain unknown parameters. Students discover what happens to the qualitative behavior of solutions to these equations as...

    Keywords: bifurcationqualitative behaviorbifurcation diagram

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    7-010-MultipleDoses-ModelingScenario
    Two multiple dose drug administration regimens are offered. A drug is to maintain a certain level (above a set minimum and below a set maximum) in the blood stream and one regimen involves bolus...

    Keywords: drug discoverystep functiondoseDiracdrug administrationinverse Laplace Transformintraveneousbolussteady drip

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    Understanding Gene Prediction Programs
    Introduces students to the key biological concepts underlying computational gene prediction. Outcomes include ability to analyze and evaluate output of gene prediction programs, and reflect on...

    Keywords: Genome annotationSEA-PHAGESgene predictiongenemarkcoding potentialcodon biassix frame translation

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    Remote sensing data processing – NEON airborne data
    Concepts of remote sensing and data logistics, and NEON remote sensing data are introduced. Students learn how to apply spatial data processing and visualization skills using R coding program to...

    Keywords: RlandscapebiomassProblem Solvingraster raster data processingspatial data visualizationvegetation indicescanopy

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    Stream Discharge Module- Beck Modification (Project EDDIE)
    In this module, students use data from the United States Geologic Survey to assess changes in stream discharge with time, calculate flood frequency, and see the effects of urbanization and flood...

    Keywords: floodsProject EDDIEurbanizationstreams

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    Bioinformatics: Investigating Sequence Similarity - A Plant Biology Approach
    This laboratory module is a modification of the original published on CourseSource with a focus on plant biology. In the final activity, students conduct a BLAST to compare histone protein...

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBIplant biologyNIBLSEalgorithmsincubatorsPlant and Fungal EvolutionBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogram

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    A Pipeline in Paradise
    I incorporated fracking into the case study instead of just focusing on building a pipeline, which allowed us to discuss fracking with this case study.
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    Globally endangered sea turtles of the Palmyra Atoll National Wildlife Refuge: A Focus on Scientific Analysis
    Based on the sea turtle case, students will (1) work on a worksheet by analyzing existing survey data, (2) conduct a literature review of two relevant research, and (3) draft a proposal for a...

    Keywords: sea turtle conservationliterature reviewResearch methodsProposal writingPalmyra Atoll

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    Modification to City Parks
    Using a jigsaw approach, students calculated species richness, Shannon's diversity index and species evenness using the City Parks wildlife data.

    Keywords: Biodiversityspecies diversity

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    Implementing an online module about tropical seed dispersal and restoration in an undergraduate ecology course in the Pacific Northwest, USA
    This “Spreading Seeds” case study introduces students to ecology of seed dispersal mutualisms, and their importance for forest restoration. The implementation plan teaching notes, and associated...

    Keywords: mutualismRestoration Ecologyspecies interactionHabitat fragmentationSeed dispersalforest recovery

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    Quantifying Bacterial Growth in the Guts and Hemolymph of Fruit Flies: Mathematical Modeling and Data Interpolation/Extrapolation
    In this activity, students will analyze raw data obtained from an experiment that explores the effect of overexpressing the Ssk protein in order to strengthen the intestinal barrier and prevent...

    Keywords: graphingexponential growthlinear modelsqbccinterpolationConcepts in Statistics and Precalculus Understanding exponential rates and linear slopesExtrapolation

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    Gene Expression in Stem Cells
    The module served as in introduction to the Gene Expression unit. It was implemented in two phases, a pre-class activity and an in-class activity to introduce chapter concepts and reinforce...

    Keywords: small group activitypre-class activityGeneral Biology

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    HSI - Student Research Journal - Vol.1 Issue 1 - Fall 2020
    The Headwaters Research Experience students have produced some fascinating research throughout our 10-week program. We encourage all to read their reports in our Vol. 1 - Issue 1 - Fall 2020...
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    Using Bioinformatics Activities to understand the Past and Present of SARS-CoV2
    We have designed a Bioinformatics activity that uses tools to identify the origins and mutations in the novel SARS-CoV2 strains.
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    When did I lose my legs? A limbless lizard tale
    Using oVERT project models students examine examples of extant traditional lizards, snakes and limbless lizards and create phylogenies based on trait and genetic data.

    Keywords: phylogeneticsevolutionary biologyHerpetologynatural history collections3D models#NGSSdigitized natural history collectionsoVertConvergent Evolution

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    Data Analysis and Cancer
    This is a flipped classroom approach, students will learn the basic content about cell-signaling, p53, and transcription factors before class. During class students will focus on data analysis...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologydata interpretationBiological Data Analysiscell cyclemacromoleculesGenetic diseaseCell signaling

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    Morphological, Anatomical and Molecular Analysis of Plant Phylogeny and Diversity
    In this lab, students perform phylogenetic analyses on morphological, anatomical and molecular data, and compare.

    Keywords: morphologyphylogenylaboratoryplantsmolecular analysisstele architecture

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