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    The Human Microbiome Biodiversity in Health and Disease
    The students will analyze the human gut and vaginal microbiomes in healthy and diseased states using diversity of bacteria as determined by 16SrRNA sequence.
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    Morphological and Molecular Analysis of Plant Phylogeny and Diversity
    In this lab, students perform phylogenetic analyses on morphological and molecular data, and compare.

    Keywords: morphologyphylogenylaboratoryplantsmolecular analysis

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    Robot vs. Disease: Using CellProfiler to model biomedical research in your classroom
    Resource from the 2015 BioQUEST Summer Workshop

    Keywords: image analysisCellProfilerfluorescence microscopymicroscopycellular analysis

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    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...

    Keywords: case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

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    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    Incorporating authentic research experiences into undergraduate labs, while shown to be particularly effective at engaging and retaining students in STEM majors, can be difficult to accomplish...

    Keywords: gene regulationmicroRNAsgene expression

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    Where Does Elsie's Hair Color Come From? A "De-Simplified" Pedigree Lesson
    Pedigree analysis is part of most Genetics curricula, but the examples traditionally used in genetics courses present phenotypes as if they were entirely and inexorably defined by genotype. This...

    Keywords: pedigreeMultifactorialphenotypic variationpenetranceexpressivityquantitative variation

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    6-068-VisualizingPredator-PreyCycles
    In this modeling scenario, we propose a gentle introduction to limit cycles using nullcline analysis and a spreadsheet graphical approach via the fourth-order Runge-Kutta method. We will be...

    Keywords: nullclinespredator-preyGeometrypredatorRunge-Kuttapreylimit cycle

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    Tag You're It: A Lesson Investigating Study Design and Survival Analysis on an American Shad Tagging Study
    In this lesson, students will learn about the various mark-recapture and tagging methods that are used in various scientific disciplines and the information they can gather. Key elements of...

    Keywords: survival analysisAmerican ShadCox Proportional Hazards ModelStudy Design

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    2017-D_Goulet-Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments
    In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The differential...

    Keywords: optimizationBiochemistrysensitivity analysischromatographymass actioncluster analysisconservation lawsdimerizationestrogen receptor protein

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    2014-Vance-Eads-Sensitivity Analysis of a Three-Species Nonlinear Response Omnivory Model with Predator Stage Structure
    We investigate a three-species nonlinear response omnivory model incorporating stage structure in the top predator. The model consists of four coupled ordinary differential equations involving...

    Keywords: stage structuresensitivity analysismortalityomnivoreomnivory modelsearch rates

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    Measuring Size and Area of Digitized Specimens using ImageJ
    Use ImageJ to analyze morphological characters in digital images of natural history specimens. Skills are transferable to many organisms and other morphological measurements.

    Keywords: ImageJnatural history collectionscourse-based research experiences (CUREs)digitized natural history collections

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    6-015-CombatingEbolaEpidemic-ModelingScenario
    This project offers students a chance to make a policy recommendation based on analysis of a nonlinear system of differential equations (disease model). The scenario is taken from the fall of 2014...

    Keywords: diseaseEbolaAnalysisPolicydecision

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    9-010-TravelingWave-ModelingScenario
    Students are taken through a traveling wave analysis of a porous medium model. While the starting point is a nonlinear partial differential equation model, after a change of variables, students...

    Keywords: traveling wavesseepage velocityporous medium

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    Single Factor Analysis of Variance (ANOVA)
    This swirl lesson introduces students to theoretical and practical concepts about single-factor ANOVA analysis and an approach to conduct this type of analysis using R.

    Keywords: ANOVATukey HSD

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    A Fun Introductory Command Line Exercise: Next Generation Sequencing Quality Analysis with Emoji!
    This resource is a fun computer-based intro to command line programming. The activity takes FASTQ NGS data files and runs a fun program called FASTQE.

    Keywords: data sciencebioinformaticsnext generation sequencingquality controlFASTQgenomicsprogrammingNIBLSElinuxmicrobiomeIllumina sequencingcommand lineFASTQEFASTPNGS analysisterminalMacemojiPhred scoreTrimmingshort read

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    Analysis of Microbiomes Using Free Web-Based Tools in Online and In-Person Undergraduate Science Courses
    Our understanding of microbiomes, or the collection of microorganisms and their genes in a given environment, has been revolutionized by technological and computational advances. However, many...

    Keywords: microbiomeDNA SubwayCyVerseCourse based undergraduate researchQIIME2ranacapa

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    A Rapid Genetic Screen Using Wisconsin Fast Plants®: A Hands-On Approach to Inheritance of de novo Mutations
    Some concepts in genetics, such as genetic screens, are complex for students to visualize in a classroom and can be cumbersome to undertake in the laboratory. Typically, very large populations are...

    Keywords: mutationInheritancegermlinesomaplant lifecycle

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    3-043-BallisticModeling-SpongeDart-ModelingScenario
    The goal of this project is for students to develop, analyze, and compare three different models for the flight of a sponge dart moving under the influences of gravity and air resistance.

    Keywords: projectile motionair resistanceballisticsdimensional analysisNewtonian mechanicssponge dartNerf gunNerf dartBuckingham's Theorem

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    1-190-IntroClass-ModelingScenario
    Students go through development of ideas in mathematical modeling with differential equations. They encounter fundamental ideas of unlimited population growth, limited population growth and a...

    Keywords: population dynamicspredator-preylogisticexponentialgraphical interpretationsqualitative analysis

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    Using Bioinformatics Activities to understand the Past and Present of SARS-CoV2
    We have designed a Bioinformatics activity that uses tools to identify the origins and mutations in the novel SARS-CoV2 strains.
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