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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Piwi Matters
    This case focuses on understanding structure and function relationships in Piwi, a protein that is critical for germline stem cell function and development of eggs in the fruit fly ovary.

    Keywords: Stem cellsmolecular visualization and analysis3D protein structure /function analysisPiwiPDBMolecular Case Study

    1307

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

    1430

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    527

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    3

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    Box-of-Lessons Review, Fall 2022 - YouTube
    This video described the working group activities for BIOME Institute 2022 - Fall working group

    Keywords: carbohydratesproteinsNucleic Acid Structurebiomolecular structurebiomolecular visualizationProtein Data Bankresources @ Molecular CaseNetBIOME 2022pilotinglipidsbiomolecules

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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

    1673

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    1948

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    COVID-19: Molecular Basis Infection Revisited One Year into the Pandemic
    This adaptation was written in Spring 2021 exactly one year after the original case and includes explorations of the emerging mutations within the spike protein

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Studyvariantsantibody

    935

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    613

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    A Case of Severe Insulin Resistance
    This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistance

    1355

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    533

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    0

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    1

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisgenetic basisPDBMolecular Case StudyMol*

    1159

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    2258

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    COVID-19: Molecular Basis of Infection-ADAPTATION
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

    1187

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    1603

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    0

    comments

    0

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    Waking up Anna
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABA

    1302

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    501

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    0

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    1

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    A "Box of Lessons" for Exploring Biomolecular Structure and Function
    Biomolecular structure and function is emphasized as a core concept in a variety of community determined educational standards for biology and chemistry. Most curricula introduce students to the...

    Keywords: bioinformaticsproteinsRNADNAmolecular visualizationbiomolecular structurebiomolecular visualizationProtein Data BankPDBMolecular CaseNet FMN

    845

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    220

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    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

    1668

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    2015

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    0

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    2

    adaptations

    Evolution of Caffeine Biosynthesis Enzymes
    This case focuses on exploring why plants make secondary metabolites like caffeine and how the enzymes required for making caffeine evolved.

    Keywords: Evolutioncaffeinemolecular visualization and analysisenzymesPDBMolecular Case Study

    1330

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    533

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    0

    comments

    0

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    The Happy Blue Baby Hemoglobin
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

    1277

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    589

    downloads

    0

    comments

    0

    adaptations

    Drugging SARS-CoV-2
    This case study leads students through the process of proposing a drug for a novel protein. The Mpro protease of SARS-CoV-2 is explored in detail within the PDB. Aligns with first semester...

    Keywords: viruscoronavirusPDBSARS-CoV-2proteasedrug design

    1233

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    347

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    BioMolViz - Development of an Inclusive Community for the Instruction of Visualizing Biomolecules (RCN-Introduction)
    BioMolViz is a community dedicated to advancing biomolecular visualization education. We provide training, teaching tools and validated visual literacy assessments. The BioMolViz Library—our online...

    Keywords: RCN-UBE Introduction

    325

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    92

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    0

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    adaptations

    Assessment of Science Inquiry
    Resource from the 2015 BioQUEST Summer Workshop

    Keywords: assessmentconceptsSoTL

    1552

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    435

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    Effects of Laptop Use on Student Learning
    Resource from the 2015 BioQUEST Summer Workshop

    Keywords: classroomcurriculumlecture slidescourselaptopstudent learningsyllabusin-class activity

    1428

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    190

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    EvolSeq
    An Excel worksheet that simulates the molecular evolution of DNA sequences.

    Keywords: EvolutionExcelmolecular evolutionDNAResources @ ESTEEM

    1159

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    227

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    adaptations

    Undergraduate Research Experiences in Computational Science at a Community College
    Resource from the 2015 BioQUEST Summer Workshop

    Keywords: computer simulationscomputational modelInterdisciplinary STEMcomputational toolscommunity colleges

    1358

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    620

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    Morphological and Molecular Analysis of Plant Phylogeny and Diversity
    In this lab, students perform phylogenetic analyses on morphological and molecular data, and compare.

    Keywords: morphologyphylogenylaboratoryplantsdiversitymolecular analysis

    1229

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    446

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