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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    2015-Zhang-EtAl-On the Selection of ODE Models with Application to Predator-Prey Dynamical Models
    We propose a computationally inexpensive approach that employs statistical estimation of the full model, followed by a combination of a least squares approximation (LSA) and the adaptive Lasso.

    Keywords: least-squares approximationSpline modelingMonte Carlo simulationsvariable selectionadaptive LASSO

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    2015-Valerie_Billard-Pharmacokinetic-pharmacodynamic relationship of anesthetic drugs - from modeling to clinical use
    The purpose of this short review is to describe the basis of pharmacokinetics and modeling, the concentration-effects relationship, and drug interactions modeling to offer to anesthesiologists and...

    Keywords: anesthesiapharmacokineticspharmacodynamicanesthetic

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    2014-Eckhoff-EtAl-Fun with maths-exploring implications of mathematical models for malaria eradication
    . In this note, four examples demonstrate both the effects of model structures and assumptions and also the benefits of using a diversity of model approaches fomalaria eradication strategies.

    Keywords: vaccinemalariamigrationeradicationseasonality

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    2010-Del-Ciello-EtAl-Modeling Disease
    We model the transmission of a disease through a population. Such modeling is very important to the study of epidemiology and the practice of medicine.

    Keywords: diseasespreadcarriessymptomaticasymptomatic

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    2009-Marten-EtAl-Derivation and analysis of an ordinary differential equation for epilepsy dynamics
    In this paper we describe how an ordinary differential equation model of corticothalamic interactions may be obtained from a more general system of delay differential equations.

    Keywords: delayepilepsy dynamicsepilepsybistabilityseizure activity

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    2014-Andre_De Ross-Modeling Population Dynamics
    This course is intended as an introduction to the formulation, analysis and application of mathematical models that describe the dynamics of biological populations.

    Keywords: predator-preycompetitionpopulationgrowthbifrucationtext

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    5-012-LipoproteinModeling-ModelingScenario
    Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic...

    Keywords: wildlifelow-density-lipoproteintracercompartment modelcholesterolblood plasmabody tissue

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    A Critical Guide to BLAST
    This Critical Guide in the Introduction to Bioinformatics series provides an overview of the BLAST similarity search tool, briefly examining the underlying algorithm and its rise to popularity.

    Keywords: NIBLSEBLASTGOBLETInstructorResources

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    Opioid crisis: exploring the neurophysiology of opioid receptor signaling
    Using this dataset, we explore how opioids affect the electrical activity of neurons when exposed to different opioid receptor agonists and antagonists.

    Keywords: opioid epidemic

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

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    COVID-19: Molecular Basis of Infection
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

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    Interconnections in The Open Ecosystem
    Presentation on open education and open science given as the keynote address at the 2019 BioQUEST & QUBES Summer Workshop

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Mentoring Pacific Island Students for Conservation
    This undergraduate internship program focuses on mentoring Pacific Island Students into conservation careers through development of skills, networks and sense of self, while being grounded in...

    Keywords: internshipconservation ecologyplace based learningSelf-Efficacycultural contextExperiential Education

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    Citations
    Published Avida-Ed article

    Keywords: EvolutioncurriculumSelectionDigital Organisms

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    Draft Version: Energy Balance Models
    This module introduces the student to the process of mathematical modeling.

    Keywords: modulemathematical modelingbenergy balanceclimate modelDIMACSResources @ DIMACSclimatein-class activityResources @ QUBES - Teaching & Referencescienceexperiment

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    PLANT Talking Points: Popcorn, endosperm and the foods we eat...
    This resource connects botany to everyday life by way of explaining what common foods we eat really are.

    Keywords: botanyplants

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    Use of Peerwise and Twitter in Open Pedagogy
    This presentation will demonstrate the use of two open tools (Peerwise and Twitter) to engage students in creating and discussing course content.

    Keywords: twitterOER

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    The Morning After: A Case Study of the Impacts of HIV on Sexual Minority Populations
    Poster on a case study around the experiences of the LGBT community related to HIV presented at the 2018 QUBES/BioQUEST Summer Workshop

    Keywords: case studypublic healthHIVSummer Workshop 2018LGBT community

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