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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

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    Serotonin in the Pocket: Non-covalent interactions and neurotransmitter binding
    This lesson introduces beginning biochemistry students to the concept of a biomolecule binding site, such as a neurotransmitter receptor site or an enzyme active site. A simple organic molecule,...

    Keywords: active sitebindingbinding sitehydrogen bondinghydrophobic effectionic interactionsnon-covalent forces

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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    Electron Location, Location, Location: Understanding Biological Interactions
    Introductory Biology courses typically introduce the structure and function of biomolecules such as proteins and nucleic acids. To understand biomolecules fully, students require knowledge of...

    Keywords: hydrogen bondshydrophobicity/hydrophilicitypolar and non-polar covalent bonds

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    Using Bioinformatics and Molecular Visualization to Develop Student Hypotheses in a Malate Dehydrogenase Oriented CURE
    Developing student creativity and ability to develop a testable hypothesis represents a significant challenge in most laboratory courses. This lesson demonstrates how students use facets of...

    Keywords: bioinformaticsNoncovalent InteractionsEnzyme CatalysisProtein Structure/function

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    It's a Substrate... It's a Protein...No - It's an Enzyme! Teaching Using 3D Serine Protease Physical Modeling Activities to Confront Misconceptions.
    Reported misconceptions of enzyme-substrate interactions highlight the necessity for better, targeted instructional tools and assessments. A series of active learning activities with corresponding...

    Keywords: Protein StructureEnzymes-Substrate InteractionsNoncovalent InteractionsGeometric ComplementaryElectronicsStereochemistrySerine Proteases

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    Understanding Protein Domains: A Modular Approach
    An understanding of protein structure, function, and interaction is central to biochemistry. One angle into this topic is to engage students in considering protein domains as modules that develop...

    Keywords: Protein Structure

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    Sequences and Properties of Gluten Proteins From Different Grains: A Virtual-Friendly Protein Laboratory
    The COVID-19 pandemic has forced much university instruction into virtual modes. As a result, many laboratory courses have either dropped content altogether or replaced hands-on activities with...

    Keywords: protein structure and functionProtein sequenceintermolecular forcesBiomacromolecules

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    A 360˚ View of COVID-19
    In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new...

    Keywords: geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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    Angiosperm Diversity in Pollination Systems
    This activity is designed for upper-level undergraduates and graduate students engaged in ecology and biodiversity sustainability studies. This activity will explore how plant-pollinator...

    Keywords: data visualizationBiodiversityplantsPlant-insect interactionsnetworkinsectsBLUEpollinators

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    Investigating the footprint of climate change on phenology and ecological interactions in north-central North America
    This is an FMN participant modification of the TIEE module "Investigating the footprint of climate change on phenology and ecological interactions in north-central North America,"...

    Keywords: ecologyfmnLectureUndergraduateData DiscoveryInstructional SettingAudience LevelAdvancedActivity LengthLess than 1 hour

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    Investigating the footprint of climate change on phenology and ecological interactions in north-central North America
    This is an FMN participant supplement for the TIEE module "Investigating the footprint of climate change on phenology and ecological interactions in north-central North America," authored...

    Keywords: ecologyLabEcological Society of AmericafmnLectureUndergraduateData DiscoveryInstructional SettingAudience LevelAdvancedActivity LengthMore than 1 hour

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    Probing Subunit Interactions in 3-Phosphoglycerate Dehydrogenase
    A research poster.

    Keywords: JoCURE

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    Downloading and Visualizing Project Data from the iNaturalist Database
    In this activity you will learn how to create a query, export, and download data from iNaturalist; load data into R; explore pollinator-plant interactions with R, and create heat map, bipartite,...

    Keywords: data visualizationplantsPlant EcologyPlant-insect interactionsnetwork#iNaturalistBLUEpollinators

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    Ocean Acidification: Predator-Prey Interactions of Intertidal Snails and Sea Stars
    This lesson discusses ocean acidification, its causes, and the potential dangers that it may pose to aquatic ecosystems by analyzing the relationship between intertidal invertebrates. While...

    Keywords: predator-prey interactionsocean acidification

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    Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab
    Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much...

    Keywords: Protein StructureproteaseEnzymechemical bondscatalysissolubility

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    Mockumentary: Parasitology Research
    A new parasite is decimating the endangered purple platytoad population! Follow scientists from the Host-Parasite Interactions group as they try to save the purple platytoad through a...

    Keywords: parasitesecological parasitologyclinical diagnostic parasitologymockumentarytranslational research

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    Investigating the footprint of climate change on phenology and ecological interactions in north-central North America
    This is an FMN participant modification of the TIEE module "Investigating the footprint of climate change on phenology and ecological interactions in north-central North America,"...

    Keywords: ecologyIntroductoryfmnLectureUndergraduateData DiscoveryInstructional SettingAudience LevelActivity LengthMore than 1 hour

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    Teaching notes for "Investigating the footprint of climate change on phenology and ecological interactions in north-central North America"
    This is an FMN participant modification of the TIEE module "Investigating the footprint of climate change on phenology and ecological interactions in north-central North America,"...

    Keywords: ecologyLabfmnLectureUndergraduateData DiscoveryInstructional SettingAudience LevelAdvancedActivity LengthMore than 1 hour

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    Investigating the footprint of climate change on phenology and ecological interactions in north-central North America
    This is an FMN participant modification of the TIEE module "Investigating the footprint of climate change on phenology and ecological interactions in north-central North America,"...

    Keywords: ecologyIntroductoryLabfmnUndergraduateData DiscoveryInstructional SettingAudience LevelActivity LengthMore than 1 hour

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