You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    Box-of-Lessons Review, Fall 2022 - YouTube
    This video described the working group activities for BIOME Institute 2022 - Fall working group

    Keywords: carbohydratesproteinsNucleic Acid Structurebiomolecular structurebiomolecular visualizationProtein Data Bankresources @ Molecular CaseNetBIOME 2022pilotinglipidsbiomolecules

    1027

    views

    187

    downloads

    0

    comments

    0

    adaptations

    Macromolecular math
    This worksheet was developed for use in an introductory biology course to review the chemical bonds and structure of biological macromolecules. A nutritional label is provided to illustrate that...

    Keywords: introductory biologycarbohydratesProtein StructureNucleic Acid Structuremacromoleculesnon-covalent interactionpolypeptidechemical bonds

    1064

    views

    1766

    downloads

    0

    comments

    0

    adaptations

    Students Authoring Molecular Case Studies
    Poster on using case studies to help students develop their skills in reading primary literature and identifying authentic scientific problems by authoring their own case studies. Presented at the...

    Keywords: case studiesProtein StructureProtein Data BankMolecular Case Study2021 BIOME

    1153

    views

    348

    downloads

    0

    comments

    0

    adaptations

    Learn genomics and bioinformatics through scientific thinking, creation and analysis (virtual and hands-on)
    Nucleic acid are biological molecules composed of nitrogen-containing bases, phosphate groups, and sugar molecules. The complimentary chemical bonding results in formation of double stranded DNA....

    Keywords: data analysisbioinformaticsnucleotidesproteinsRNAgenomicsScientific communicationscientific writingDNAmodelling scientific thinkinggenescientific thinkingcreation

    271

    views

    27

    downloads

    0

    comments

    0

    adaptations

    Amino Acid Frequency
    This module introduces expected frequencies in the context of understanding amino acid composition. It is intended for an introductory biology audience.

    Keywords: Probabilitylinear regressionamino acidsOpenStaxGenetic InformationAminoAmino Acid Freuency

    1692

    views

    385

    downloads

    0

    comments

    0

    adaptations

    Functional and structural analysis of Amylase activity
    This exercise was developed to allow students to apply the scientific method and use their knowledge of enzymes to investigate the relationship between enzyme activity and structure. Students...
    986

    views

    2965

    downloads

    0

    comments

    0

    adaptations

    Vaccine Development and Testing
    Scientists have the tools and knowledge to develop safe, effective vaccines, from trials to vials. This resource addresses the process by which vaccines are designed, tested and regulated. Key...

    Keywords: immunology educationvaccine literacyvaccine hesitancy

    219

    views

    90

    downloads

    0

    comments

    0

    adaptations

    Teaching Protein Structure Modeling
    New strains of microbes have been regularly discovered and brought into a laboratory for study in many different directions. When a new microbial genome is sequenced and assembled, the homologues...

    Keywords: Microbiology Educationbioinformaticsprotein structure modeling

    341

    views

    34

    downloads

    0

    comments

    0

    adaptations

    Electron Location, Location, Location: Understanding Biological Interactions
    Introductory Biology courses typically introduce the structure and function of biomolecules such as proteins and nucleic acids. To understand biomolecules fully, students require knowledge of...

    Keywords: hydrogen bondshydrophobicity/hydrophilicitypolar and non-polar covalent bonds

    2590

    views

    636

    downloads

    0

    comments

    0

    adaptations

    Serotonin in the Pocket: Non-covalent interactions and neurotransmitter binding
    This lesson introduces beginning biochemistry students to the concept of a biomolecule binding site, such as a neurotransmitter receptor site or an enzyme active site. A simple organic molecule,...

    Keywords: active sitebindingbinding sitehydrogen bondinghydrophobic effectionic interactionsnon-covalent forces

    2686

    views

    323

    downloads

    0

    comments

    0

    adaptations

    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisgenetic basisPDBMolecular Case StudyMol*

    1161

    views

    2258

    downloads

    0

    comments

    0

    adaptations

    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

    207

    views

    16

    downloads

    0

    comments

    0

    adaptations

    An Interactive Protocol for In-Classroom DNA Extraction
    Using commonly available materials, this tool allows students to extract DNA, exploring DNA chemistry and the principles of experimental design and execution. We take a “Choose Your Own...

    Keywords: geneticsDNAbiochemical structure and function

    1820

    views

    180

    downloads

    0

    comments

    0

    adaptations

    Predicting and classifying effects of insertion and deletion mutations on protein coding regions
    Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...

    Keywords: mutationcentral dogmatranslationframeshift

    3033

    views

    566

    downloads

    0

    comments

    0

    adaptations

    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.

    Keywords: bioinformaticsNIBLSEProtein StructureDNAmolecular modelinggenotypephenotypeCourseSourcecomputational modelingcentral dogmaplant leaf structure

    1314

    views

    291

    downloads

    0

    comments

    0

    adaptations

    An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure
    Gene structure, transcription, translation, and alternative splicing are challenging concepts for many undergraduates studying biology. These topics are typically covered in a traditional lecture...

    Keywords: bioinformaticsGenome BrowsergenomicsRNAseqsplicingComputer ModelGene Structure

    7228

    views

    1383

    downloads

    0

    comments

    0

    adaptations

    Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages
    The goal of this lesson is to introduce students to the lytic and lysogenic cycles of T4 and lambda bacteriophages, respectively, using student-centered pedagogies. Bacteriophages are viruses that...

    Keywords: bacteriophagesLysogenic cycleLysogenyLytic cycle

    4693

    views

    2311

    downloads

    0

    comments

    0

    adaptations

    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

    1402

    views

    1183

    downloads

    0

    comments

    1

    adaptations

    Understanding Gastric Acid Secretion: An Active Learning Approach
    The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the...

    Keywords: diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit

    1057

    views

    525

    downloads

    0

    comments

    0

    adaptations

    Taking the Hassle out of Hasselbalch
    Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the...

    Keywords: pHdrug uptakeHenderson-Hasslbalch equationmedical applicationspKa

    1468

    views

    349

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search