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    Investigating human impacts on stream ecology: locally and nationally
    TIEE Module- How does nutrient pollution impact stream ecosystems locally and nationally? This is an adaptation of the module that includes statistical testing and links sections to a lab report...
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    SUMS4Bio - Video tutorials in math and stats for biology students
    Links to videos and pdf tutorials for core mathematical and statistical concepts used in biology

    Keywords: Probabilitystatisticsmathematicsvideoschi-squaredExcelBar Graphsline graphsScatter Plotsp-valuest-testsExponentsLogarithmsproportionsRatiosbinomialdata typessummary statisticsfrequency histogramsResources @ SUMS4BioPresentation

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    Spreadsheet Data Analysis Tutorial Series
    This series of self-paced tutorials show how to analyze data using a spreadsheet program.

    Keywords: Resources @ HHMI - BioInteractiveScientific ProcessStatistics and MathScientific MethodologyHigh School

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    2014-Blomhøj-EtAl-Compartment models
    An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a...

    Keywords: concentrationkineticsphysiologycompartmentsalttankbalancereactionsminkbathtub

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    1-077-RLMSimSeriesCircuit-ModelingScenario
    In this validation setup, the first order linear ordinary differential equation governing a small signal RL series AC circuit is solved analytically and the results are compared with the data...

    Keywords: MeasurementcircuitvoltagecurrentvalidationSPICERL circuitMultilsim

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    5-012-LipoproteinModeling-ModelingScenario
    Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic...

    Keywords: wildlifelow-density-lipoproteintracercompartment modelcholesterolblood plasmabody tissue

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    5-030-AirshedSulphur-ModelingScenario
    Temperature inversions and low wind speeds trap air pollutants in a mountain valley for a period of time. Gaseous sulfur compounds are a significant air pollution problem. We offer a model for...

    Keywords: sulphurpollutionairshedhydrogen sulfidesulfur dioxide

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    4-050-ResonanceBeats-ModelingScenario
    We study what can happen when a pure oscillator (no damper) is driven by a forced vibration function which has the same or close to the same natural frequency as the system it is driving.

    Keywords: Spring 2020 workshopvibrationtuningdriverresonanceforced vibrationundampedbeatsnaturl frequency

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    Phenotypic plasticity and predation
    Students predict changes to tadpole morphology and coloration after considering characteristics of the predator species and the prey themselves then test their own hypotheses (typically with...

    Keywords: RExcelimage analysisgraphingt-testsfrequency histogramsdata visualizationANOVAhypothesis formulationpredator-prey interactionsphenotypic plasticity

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    Enhancing the Microscopy Skills of Non-Science Majors and Nursing Microbiology Students: Promoting the Practice of Observing Multiple Fields of View Using Blood Smear Slides
    One of the challenges in teaching microscopy is having students scan multiple fields of view at high power magnification. Many times, students will feel this unnecessary, especially when presented...

    Keywords: Microscopy SkillsBlood SmearsBlood Disorders

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    Differential Gene Expression during Xenopus laevis Development
    In Developmental Biology classes, students are challenged with understanding how differential gene expression guides embryonic development. It can be difficult for students to realize that genes...

    Keywords: gene expressionXenopusearly developmentembryofertilizationin situ hybridization

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    My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships
    To facilitate understanding of the fundamental genetic concept of the genotype-phenotype relationship in our introductory biology students, we designed an engaging multi-week series of related...

    Keywords: gel electrophoresissequence analysiscanine geneticsdeoxyribonucleic acid (DNA)dog coat morphologygenotype and phenotypemutationsPolymerase chain reaction (PCR)single nucleotide polymorphism (SNP)

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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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    The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories
    Inquiry-based undergraduate laboratories provide the opportunity to engage students in a research experience that improves scientific thinking, but such activities can be difficult to develop and...

    Keywords: protein structure and functionhuman genetic variationmuscle physiology

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    A CURE-based approach to teaching genomics using mitochondrial genomes
    There is an abundance (currently over 1016 DNA bases) of publicly available genetic sequence data and a dearth of trained genomicists to process and interpret it, necessitating more trained...

    Keywords: proteinsMitochondrial GenomesNuclear GenomesrRNAtRNA

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    A Structured Inquiry-Based Module for the Undergraduate Cell Biology Laboratory That Teaches Fundamental Concepts of Cell Differentiation
    Pedagogical research in science education has shown that students effectively learn science by doing science. As a result, there is increased interest in bringing research-like experiences into the...

    Keywords: fluorescence microscopygene expressionpolymerase chain reactionCell Structurecell culturewestern blottingdifferentiationreverse transcription

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    Analyzing Data on Behavioral and Immunological Effects of Inflammation in Mice
    In this activity, students will learn about behavioral and immunological responses to a bacterial infection. The activity emphasized the host’s responses rather than bacterial manipulation of the...

    Keywords: Vision and Changedata analysisImmunologybehaviorphysiologyinflammationinterdisciplinary educationAntigenmouseImmunoReachSicknessleukocyteneutrophilLipopolysaccharideacute phase response

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    Gene Expression in Stem Cells
    The module served as in introduction to the Gene Expression unit. It was implemented in two phases, a pre-class activity and an in-class activity to introduce chapter concepts and reinforce...

    Keywords: small group activitypre-class activityGeneral Biology

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    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    Keywords: gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

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    Using Musical Instruments to Model Negative Feedback in the Hypothalamo-Pituitary-Target Gland Axes
    Homeostasis and negative feedback are crucial, yet difficult, concepts for undergraduates, particularly in the context of the hypothalamo-pituitary axes. This interactive activity was designed to...

    Keywords: cell-cell communicationhomeostasisnegative feedback

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