You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    Translating Co-Translational Translocation
    Understanding the process of proteins targeting to specific locations within a cell is a fundamental part of cell biology. Synthesis of proteins by co-translational translocation, which also...

    Keywords: Topologyco-translational translocationendoplasmic reticulumprotease protection assaysecretory proteinssignal sequencetransmembrane proteins

    2387

    views

    488

    downloads

    0

    comments

    0

    adaptations

    A tale of two globins: hemoglobin and myoglobin and oxygen transport
    Hemoglobin and myoglobin are two related proteins important in oxygen binding and transport to cells. However, unlike myoglobin, hemoglobin exhibits positive cooperativity in oxygen binding. Oxygen...
    833

    views

    643

    downloads

    0

    comments

    0

    adaptations

    2014-Hrydziuszko-EtAl-Mathematical Two-compartment Model of Human Cholesterol Transport
    We develop a two-compartment mathematical model to investigate cholesterol transport in the circulatory system and its de novo synthesis in the liver.

    Keywords: metabolic syndromecompartmentcholesteroltwo-compartment modelcholesterol transport

    139

    views

    89

    downloads

    0

    comments

    0

    adaptations

    Cystic Fibrosis Mechanism and Treatment
    This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymacromoleculesGenetic diseaseCell Structure & Function

    1203

    views

    233

    downloads

    0

    comments

    0

    adaptations

    Nucleo-cytoplasmic Transport
    This module introduces exponential decay and the rate of influx in the context of understanding the transport of molecules from the cytoplasm to the nucleus. It is intended for an introductory...

    Keywords: exponential equationsCell StructureCell Growth

    796

    views

    156

    downloads

    0

    comments

    0

    adaptations

    Translocation of Nutrients in the Phloem: Dixon's Paradox
    This module introduces the Dixon equation in the context of understanding nutrient transport through sieve tubes. It is intended for an introductory biology audience.

    Keywords: plant physiologylinear regressionlinear equations

    1289

    views

    205

    downloads

    0

    comments

    0

    adaptations

    Translocation of Nutrients in the Phloem: Poiseuille's Equation
    This module introduces the Poiseuille equation in the context of understanding nutrient flow in plant cells. It is intended for an introductory biology audience.

    Keywords: plant physiologycalculushyperbolic equationsrates of change

    1174

    views

    235

    downloads

    0

    comments

    0

    adaptations

    Cellular Respiration and pH: blocking the electron transport chain and its effects on the proton gradient, pH, and ATP production
    This module contains exercises designed to help students describe the stages of cellular respiration and quantify the energy molecules produced. Students will predict the region of higher proton...

    Keywords: introductory biologyQuantitative reasoningquantitative biologyinterdisciplarycell functionInterpreting GraphsATPpHCellular RespirationEnergy transformationsElectron flowNIQBC2. Data and GraphsC4. mathematical modelsC1. Numeracyproton gradientelectron transportelectron transport blockersFADH2chemiosmosisATP synthaseNADHproton concentration

    1700

    views

    513

    downloads

    0

    comments

    0

    adaptations

    1986-Istvan_Gyori-Connections between compartment systems pipes and integro-differential equations
    In this paper we give the mathematical description of models in which the mass transport between compartments requires a given definite time or transit times are distributed according to given...

    Keywords: physiologypipelinecompartmentbloodcirculationintegro-differential equation

    202

    views

    55

    downloads

    0

    comments

    0

    adaptations

    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecompartment modelcholesterolhigh blood cholesterol

    141

    views

    85

    downloads

    0

    comments

    0

    adaptations

    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis

    125

    views

    73

    downloads

    0

    comments

    0

    adaptations

    Learn Biological Sciences and Chemistry through cellular transport and concentration ( online and hands-on)
    Osmosis is a process by which by which solvent move from a region of lower solute concentration to region of higher solute concentration through a semi-permeable membrane. Cells utilize the process...

    Keywords: statisticsdata analysisbiologycell biologyconcentrationskillscellchemistryOsmosisSpectrophotometersolutionsolutesolvent

    447

    views

    69

    downloads

    0

    comments

    0

    adaptations

    Seed Dispersal in Tropical Forests
    In this activity, students use data from published studies to understand patterns of seed dispersal and apply these ideas to the design of a conservation area. This was applied through the lens of...

    Keywords: ecologyResources @ HHMI - BioInteractivecommunityplantsdiversityScientific Process

    2352

    views

    711

    downloads

    0

    comments

    0

    adaptations

    Teaching Cell Structures through Games
    As the basic unit of life, cells are a foundational concept for all of biology. Before students can appreciate how eukaryotic cells function either in isolation or in higher order and multicellular...

    Keywords: Cell Structurecell organellesTransmembrane Transport

    5336

    views

    1388

    downloads

    0

    comments

    0

    adaptations

    2017-Fred_Adler-Mathematically Modeling Asthma
    Our Asthma models have examined how a viral infection can tip the immune system into a different state, with the potential to predispose an individual to future asthma

    Keywords: infectionasthmaimmune responserhinovirus

    144

    views

    100

    downloads

    0

    comments

    0

    adaptations

    Lights, Camera, Acting Transport! Using role-play to teach membrane transport
    Lights, Camera, Acting Transport! is an active and unique role-play exercise designed to teach introductory biology students basic concepts of passive and active membrane transport. The activity...

    Keywords: ATPcarrierschannelsco-transportelectrogenic pumpfacilitated diffusionmembrane transportpassive transportprimary active transportsimple diffusion

    8472

    views

    1185

    downloads

    0

    comments

    0

    adaptations

    Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter
    While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division...

    Keywords: DiffusionActive transportfacilitated diffusionNecessary and sufficientTransport proteins

    2118

    views

    491

    downloads

    0

    comments

    0

    adaptations

    Modeling the lac Operon to Understand the Regulation of Gene Expression in Prokaryotes
    This resource is a recitation activity designed for an introductory biology course in which students explore a lac operon simulation (https://qubeshub.org/resources/phetlacoperon).

    Keywords: simulationLac Operon

    1541

    views

    730

    downloads

    0

    comments

    0

    adaptations

    Hemoglobin Evolution
    This module introduces equations describing blood viscosity and oxygen transport in the context of understanding the evolution of red blood cells. It is intended for an introductory biology audience.

    Keywords: calculushyperbolic equationsAnimal Physiologyparabolic equationsmaxima

    1047

    views

    192

    downloads

    0

    comments

    0

    adaptations

    Metabolism for Energy and the Respiratory Quotient
    This module introduces the respiratory quotient in the context of understanding how metabolism is affected by environmental conditions. It is intended for an introductory biology audience.
    651

    views

    350

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search