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    5-012-LipoproteinModeling-ModelingScenario
    Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic...

    Keywords: wildlifelow-density-lipoproteintracercompartment modelcholesterolblood plasmabody tissue

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    5-015-RunnersSynchronize-ModelingScenario
    In this modeling scenario we practice finding and classifying equilibria of a one-variable differential equation. We do this in the context of a phase model which is often a simpler way of studying...

    Keywords: predatorAutonomous equationsoscillationcoupled oscillatorsynchronyrunnerpreyKuramato model

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    6-015-CombatingEbolaEpidemic-ModelingScenario
    This project offers students a chance to make a policy recommendation based on analysis of a nonlinear system of differential equations (disease model). The scenario is taken from the fall of 2014...

    Keywords: diseaseEbolaAnalysisPolicydecision

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    1-009-ICUSpread-ModelingScenario
    We offer students the opportunity to model the percentage of voluntary nonprofit hospitals in the United States with Intensive Care Units during the period of 1958-1974.

    Keywords: logisticsum of square errorsIntensive Care Unithospitalspread

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    3-020-ChordPathTime-ModelingScenario
    Using Newton's Second Law of motion we can determine the time it takes for a mass to slide along a chord of a vertical circle from high point to any point along the circle. Initially, the result is...

    Keywords: Unit CirclepathfallinggravitychordNetwon's Second Law of Motion

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    10-001-TilingHallway-ModelingScenario
    Students investigate difference equations through tiling hallways. They observe patterns in the tiling which lead to a difference equation. Solutions will be calculated by iteration. and the shift...

    Keywords: Geometryiterationtilingrecurrenceshift operatorpatternsclosed formanalytic solution

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    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    Keywords: gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

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    The Mathematics of Voting Systems: Plurality, Runoff and Ranked Choice
    In this five-day interdisciplinary math and social studies unit, students use math to create informed opinions about the three most common voting systems in the United States: plurality, runoff and...

    Keywords: mathematicsInterdisciplinary STEMInterdisciplinary Mathematics Educationinterdisciplinary math educationvoting

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    A How to Guide and Template for Designing a Puzzle Based Escape Room Game
    Educational games are one active and effective way of engaging students with material while also providing additional motivation to tackle challenging concepts. A particularly popular game concept...

    Keywords: Problem SolvingCollaborative WorkCorrect Misconceptions

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    Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation
    Success in biochemistry and other life science courses requires that students understand important biological concepts. One of these concepts is how gene regulation ensures that homeostasis is...

    Keywords: gene regulationinducible operonProkaryotic cellPhosphoenolpyruvate transferase system (PTS)

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    Interpreting the Pseudocot Phylogeny
    Students use physical characteristics, genetics, and a fossil record of hypothetical flowering plants to develop fundamental phylogenetic tree-building skills.
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    Meiosis Remodeled: Inclusion of New Parts to Poppit Bead Models Enhances Understanding of Meiosis
    A long-standing tradition uses strings of poppit beads of different colors to model meiosis, especially to show how segments of paired homologous chromosomes are recombined. Our use of orthodontic...

    Keywords: meiosischiasma formationchromosome recombination

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently...

    Keywords: modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

    Keywords: transcriptioncentral dogmatranslationsequence analysisDNA replicationgenetic variants

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    Teaching Cancer Biology Through a Lens of Social Justice
    The biology classroom is not separate from the greater context of society; social issues can and should be presented in connection with the content. Here we present an example of antiracist...

    Keywords: assessmentcancersocial justicePOGILAlignmentPublic ExamPublic

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    How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion
    The function of the kidneys is to help maintain a constant internal environment (homeostasis) by regulating the volume and chemical composition of the blood. This regulation occurs via three...

    Keywords: collecting ductexcretionglomerular filtration rate (GFR)nephron tubulereabsorptionrenal corpusclesection

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    From Dirt to Streptomyces DNA
    The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular...

    Keywords: MetabolismAntibiotic productionrRNA genesSecondary metabolitesStreptomyces

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    Understanding Restriction Enzyme Digests
    Prior to submitting genomic DNA for sequencing, SEA students perform a restriction endonuclease digest with several enzymes, which provides a fast and cost-effective way of quickly screening...
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    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

    Keywords: datatranscriptionvirustranslationprotein functionmembrane transportPredictions

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    Science and Society: Integrating Historical Science Materials Into an Undergraduate Biology Course
    Vision and Change in Undergraduate Biology Education (American Association for the Advancement of Science, 2011) stresses the importance of fostering an understanding of the relationship between...

    Keywords: infectious diseasevaccinationbacteriavirusesantibiotics

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