You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    COVID-19: On the way to a vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

    1072

    views

    3966

    downloads

    0

    comments

    0

    adaptations

    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

    1735

    views

    2220

    downloads

    0

    comments

    2

    adaptations

    COVID-19: Molecular Basis of Infection
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

    2003

    views

    656

    downloads

    0

    comments

    2

    adaptations

    2017-Bonin-EtAl-Mathematical modeling based on ordinary differential equations - promising approach to vaccinology
    As a proof of concept, we developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data...

    Keywords: immune systemyellow fevercomputational immunologycomputational vaccinology

    125

    views

    47

    downloads

    0

    comments

    0

    adaptations

    2016-Bonin-EtAl-Mathematical modeling based on ordinary differential equations-vaccinology
    We developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature.

    Keywords: Immunologyimmune systemAntigenvaccinologyyellow fever

    137

    views

    73

    downloads

    0

    comments

    0

    adaptations

    COVID-19: Molecular Basis of Infection-ADAPTATION
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

    1247

    views

    1683

    downloads

    0

    comments

    0

    adaptations

    2020-Chen_Et_Al-MathModel_Simulation_Phase-Based_Transmissability_Corona_Virus
    In this study, we developed a Bats-Hosts-Reservoir-People transmission network model for simulating the potential transmission from the infection source (probably be bats) to the human infection.

    Keywords: basic reproduction numbercoronavirusnext generation matrixtransmissibilitynovel coronavirus

    105

    views

    37

    downloads

    0

    comments

    0

    adaptations

    1-038-Ebola-ModelingScenario
    Students will use data published by the World Health Organization to model the 2014 outbreak of the Ebola virus in West Africa. We begin with a simple exponential growth model and move through the...

    Keywords: population dynamicsdata analysisexponential growthEbolalogisticepidemic

    1128

    views

    4006

    downloads

    0

    comments

    0

    adaptations

    2008-Yang-EtAl-Differential Equation Model of HIV Infection of CD T-Cells with Delay 
    Abstract: An epidemic model of HIV infection of CD4+ T-cells with cure rate and delay is studied. We include a baseline ODE version of the model, and a differential-delay model with a discrete time...

    Keywords: virusT cellsHopf bifurcationendemic equilibrium

    114

    views

    37

    downloads

    0

    comments

    0

    adaptations

    Connecting Viral Pandemics to Ecological Population Growth Models
    In this activity students use the HHMI Population Growth Models interactive to explore R0 for diseases and discuss the importance of connecting population ecology to current events like the...
    1793

    views

    803

    downloads

    0

    comments

    0

    adaptations

    Drugging SARS-CoV-2
    This case study leads students through the process of proposing a drug for a novel protein. The Mpro protease of SARS-CoV-2 is explored in detail within the PDB. Aligns with first semester...

    Keywords: viruscoronavirusPDBSARS-CoV-2proteasedrug design

    1293

    views

    370

    downloads

    0

    comments

    0

    adaptations

    Investigating the Ecology of Mosquitoes and Birds in Hawaii
    Examining biotic and abiotic environmental factors explain the historic, present, and future prevalence and range of avian malaria in Hawaii. The activity also asks how this affects local...

    Keywords: data analysisintroductory biologyInvasive SpeciesbirdsHawaii County

    1421

    views

    988

    downloads

    0

    comments

    0

    adaptations

    2014-Murillo-EtAl-Vertical Transmission in a Two-Strain Model of Dengue Fever
    The model is used to show that lower transmission rates of DENV-2 Asian are sufficient for displacing DENV-2 American in the presence of vertical transmission.

    Keywords: Peruvector-host modeldengueepidemmiologyvertical transmission

    103

    views

    47

    downloads

    0

    comments

    0

    adaptations

    2020-Ciaroshi-How_COVID-19_Spreads_MathModels
    On December 31, 2019, the Chinese city of Wuhan reported an outbreak of a novel coronavirus (COVID-19) that has since killed over 4,200 people. As of March 11, 2020, over 118,000 infections—have...

    Keywords: diseasecovidoutbreakWuhancoronoavirus

    172

    views

    45

    downloads

    0

    comments

    0

    adaptations

    6-015-CombatingEbolaEpidemic-ModelingScenario
    This project offers students a chance to make a policy recommendation based on analysis of a nonlinear system of differential equations (disease model). The scenario is taken from the fall of 2014...

    Keywords: diseaseEbolaAnalysisPolicydecision

    615

    views

    535

    downloads

    0

    comments

    0

    adaptations

    Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts
    Lesson on what it means for biological processes to be Poissonian, published in CourseSource

    Keywords: quantitative biologybioinformaticsmicrobiologyphysicsNIBLSEHIVCourseSourcemultiplicity of infectionPoisson Distribution

    1331

    views

    277

    downloads

    0

    comments

    0

    adaptations

    2017-Fred_Adler-Mathematically Modeling Asthma
    Our Asthma models have examined how a viral infection can tip the immune system into a different state, with the potential to predispose an individual to future asthma

    Keywords: infectionasthmaimmune responserhinovirus

    125

    views

    84

    downloads

    0

    comments

    0

    adaptations

    6-003-SchoolFluEpidemic-ModelingScenario
    We offer a model of the spread of flu in a school dormitory and are asked to find when the flu levels reach their peak and explain long term behavior of the spread of the flu.

    Keywords: infectionepidemicSIR modelflupeakschool children

    152

    views

    114

    downloads

    0

    comments

    0

    adaptations

    The Correlation Between SARS-CoV-2 RNA in Wastewater and Rising COVID-19 Vaccination Rates, in Los Angeles California
    The COVID-19 pandemic has undoubtedly impacted everyone around the globe. In 2020, many countries entered into a lockdown, transforming daily lifestyles into isolation. The SARS-CoV-2...

    Keywords: RNASARS-CoV-2wastewater

    515

    views

    92

    downloads

    0

    comments

    0

    adaptations

    Investigating Evidence for Climate Change (Project EDDIE)
    This multi-part activity allows students to discover the relationships between CO2 and temperature and how these variables have changed over time using real-world data.

    Keywords: Excelclimate changeGlobal Temperature Changeco2ice core data

    1513

    views

    831

    downloads

    0

    comments

    1

    adaptations

    Close

    Home

    Search