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    Calculating Lifetime Cancer Risk Resulting from DNA Replication
    An expanded case study adapted from an HHMI Data Point on Cell Division and Cancer Risk using Figure 1 from Tomasetti, C. and Vogelstein, B. (2015).

    Keywords: cancerScientific ProcessStatistics and MathScientific Methodologybiology of cellscell growth and divisionHigh School

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    Cell Division and Cancer Risk Data Point
    Cancer is typically attributed to hereditary and environmental factors, but these only explain a fraction of overall cancer risk. This activity explores a third factor.

    Keywords: Resources @ HHMI - BioInteractivecancerScientific ProcessStatistics and MathScientific Methodologybiology of cellscell growth and divisionHigh School

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    COVID-19 Model
    This Excel worksheet implements an SEAIHRD model for Covid-19 (Susceptible, Exposed, Asymptomatic infective, symptomatic Infective, Hospitalized infective, Recovered, Deceased).

    Keywords: infectious diseaseCOVID19

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    The Effects of Invasive Primary Producers on Native Primary Consumers
    In this experiment, the effect of the invasive primary producer, Carpobrotus edulis on the native primary consumer, Acheta domesticus, was studied. The purpose of this experiment was to identify...

    Keywords: Invasive Species

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    Global Dietary Habits in Relation to Adult Obesity
    With global obesity rates continually increasing, an analysis of the relationship between dietary patterns and global obesity rates was performed with datasets representing sugar consumption,...

    Keywords: dietglobal healthObesity

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    2017-Andras_Domokos-Differential Equations - Theory and Applications – Notes
    This is a terrific set of notes with models and applications woven into the material at every opportunity and data as well. This is introductory differential equations with attention to detail and...

    Keywords: Newton's Second Law of MotionNewton's Law of Coolingbiochemical reactionsPoiseuille’s Lawstopping distance

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    2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
    This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.

    Keywords: concentrationphysiologydrugslag timeExtravascularPharamacokineticspeak time

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    1-125-DiceyPopulation-ModelingScenario
    We offer students an opportunity to generate data for their team on a death and immigration model using 12 and 20 sided dice and then pass on the data to another student team for analysis with a...

    Keywords: simulationimmigrationdeathdice

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    2005-P_Howard-Modeling with ODE
    In these notes we consider three critical aspects in the theory of ordinary differential equations: developing models of physical phenomena, mathematically well-posed, solving ODE numerically .

    Keywords: Fluid Mechanicscompartmentpopulationsvariational methodsHamiltonian mechanics

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    2002-Nelson-Perelson-Mathematical analysis of delay differential equations models of HIV-1 infection
    We develop and analyze a set of models that include intracellular delays, combination antiretroviral therapy, and the dynamics of both infected and uninfected T cells.

    Keywords: infectionHIVT cells

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    1999-PS_Crooke-S_Hota_JJ_Martini-JR_Hochkiss-A Mathematical Model for Carbon Dioxide Exchange
    A mathematical model is presented to study the effect of Tracheal Gas Insufflation (TGI) on the alveolar ventilation during passive, mechanical ventilation.

    Keywords: mechanical ventilationventilationcarbon dioxide exchangetracheal gas insufflationalveolar ventilationshunttwo-compartment model

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    1981-Nielsen-Rosenfeld-Substantive Interpretations of Differential Equation Models
    The use of differential equations models to study social processes has been increasing rapidly. There are, however, ambiguities in the interpretation of the parameters of these models.

    Keywords: sociologypoliticsintragenerational mobilitypolitical mobility

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    1981-Nielsen_Francois-Rachel_Rosenfeld-Substantive_Interpretations_of_Differential_Equation_Models
    The interpretation of parameters of dynamic models is illustrated with reference to research on two substantive topics: political mobilization and intragenerational mobility.

    Keywords: differential equationsdynamical systemsFirst order linearintragenerational mobilitypolitical mobilizationmobility

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    2020-Ciaroshi-How_COVID-19_Spreads_MathModels
    On December 31, 2019, the Chinese city of Wuhan reported an outbreak of a novel coronavirus (COVID-19) that has since killed over 4,200 people. As of March 11, 2020, over 118,000 infections—have...

    Keywords: diseasecovidoutbreakWuhancoronoavirus

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    1-041-AirToTop-ModelingScenario
    One common rule taught to SCUBA divers is to ascend no faster than thirty feet per minute. In this project we will examine safe variable ascent rates, time required for a safe ascent using variable...

    Keywords: SCUBAascentair managementbreathingdivingunderwater

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    1-073-WaterExitBottle-ModelingScenario
    We offer an experiment in which data is collected to ascertain a parameter in the differential equation formulation of Torricelli's Law for water flow out of a cylindrical container.

    Keywords: datawaterflowTorricelli's Lawbottle

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    1-095-RatingChessPlayers-ModelingScenarios
    The goal of this activity is to have students build a mathematical model involving a system of first order difference equations from a verbal description of a scenario.

    Keywords: simulationchessElo's methodchess rating

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    1-137-SheepGraze-ModelingScenario
    In this activity, students will apply graphical analysis (such as phase lines) to determine the long-term predictions of a differential equation model for pasture grass using two different formulas...

    Keywords: herbivoreplantphase linesbifurcationoverexploitationsheepgraze

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    5-030-AirshedSulphur-ModelingScenario
    Temperature inversions and low wind speeds trap air pollutants in a mountain valley for a period of time. Gaseous sulfur compounds are a significant air pollution problem. We offer a model for...

    Keywords: sulphurpollutionairshedhydrogen sulfidesulfur dioxide

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    6-019-EnablingEpidemicExploration-ModelingScenario
    We became aware of several interesting possibilities for a modeling opportunity with data and we invited you to explore the several routes to parameter estimation in a SIR model with respect to the...

    Keywords: Akaike Information CriterionMichaelis-Mentenepidemicsaturationgradientleast sum of square errors

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