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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    COVID-19: On the way to a vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Piwi Matters
    This case focuses on understanding structure and function relationships in Piwi, a protein that is critical for germline stem cell function and development of eggs in the fruit fly ovary.

    Keywords: Stem cellsmolecular visualization and analysis3D protein structure /function analysisPiwiPDBMolecular Case Study

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    Using Digitized Collections-Based Data in Research: A Hands-On Crash Course in Ecological Niche Modeling
    Step-by-step, hands-on instruction on ways to access and download these specimen data, how to process climate layer data, and how to apply Maxent software to construct ecological niche models.

    Keywords: ecology labbiodiversity informaticsnatural history collectionsMicrosoft Excelbiodiversity collectionsRstatsecological niche modelingQGISENMToolsMaxent

    1936

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    558

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    Using Synthetic Biology to Teach Data Science
    Poster and supplemental materials on using synthetic biology to introduce students to meaningful data mining, analysis, and application to engineering novel biological constructs.
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    Body Size Constraints in Xylem Feeding Insects: Allometric Relationships
    This module introduces body size constraints of xylem-feeding insects in the context of understanding allometric relationships. It is intended for an introductory biology audience.

    Keywords: allometryRatiosexponential equationslogarithmic equationsGenetics and Evolution

    915

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    170

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    2018-Eduardo-Sontag-Lecture_Notes_on_Mathematical_Systems_Biology
    I am often asked if it is OK to use these notes in courses at other universities. The answer is “of course!” though I strongly suggest that a link to my website be provided, so that students can...

    Keywords: biologytextbooksystemsdyanmical system

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    Teaching about fatherless snakes in a prison classroom
    Developing a course for the first time as a graduate student is challenging. When I first taught introductory biology with the Cornell Prison Education Program, I struggled to design and adapt...

    Keywords: meiosismitosisReproduction

    475

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    Exploration of the Human Genome by Investigation of Personalized SNPs
    Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To...

    Keywords: UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

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    Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination
    Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom,...

    Keywords: nucleotidessequencingDNAgel electrophoresisChain Termination

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    A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation
    Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is...

    Keywords: mutationProtein Structureethicscentral dogmahuman disease

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    SARS-CoV-2: Understanding, Applying and Communicating Science
    The ability to integrate process of science training with necessary skills in applying and communicating core theories in biological science and biology quantification, has been brought into focus...

    Keywords: process of science#COVID19 #SARSCOV2 #SciComm #studentdiscovery

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    Venom Diversity & Evolution in Reptiles and Amphibians - An education module for university students
    This module contains information for a three part series introducing the venom system in reptiles and discussing it in an evolutionary context. In the first part venom and its ecological roles are...

    Keywords: geneticsEvolutionecologyHerpetologyAmphibans and ReptilesVenom

    1014

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    SARS-CoV-2: Understanding, Applying and Communicating Science
    The ability to integrate process of science training with necessary skills in applying and communicating core theories in biological science and biology quantification, has been brought into focus...

    Keywords: #COVID19 #SARSCOV2 #SciComm #studentdiscovery

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    Studying phylogeny by producing phylogenetic trees of primates using morphological and molecular characteristics.
    An assignment constructing phylogenetic trees using shared, derived morphological traits and molecular differences among 18 primate species and two outlier species has been developed. Skull and...
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    Data is the New Science - Modified and combined with Following the Data Module
    In this module, students will be introduced to some emerging biodiversity data resources. They will be asked to think critically about the strengths and utility of these data resources and apply...

    Keywords: data in the classroombiodiversity informaticsnatural history collection

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    Data is the New Science
    In this module, students will be introduced to some emerging biodiversity data resources. They will be asked to think critically about the strengths and utility of these data resources and apply...

    Keywords: data in the classroombiodiversity informaticsnatural history collection

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    E. coli Citrate Use
    EvoEd module on citrate use in E.coli

    Keywords: modulephylogeneticsecologycell biologymolecular genetics

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    From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design
    Engaging first generation underrepresented minority students in the process of inquiry in developmental biology is important to increase diversity in future graduate STEM education. One important...

    Keywords: experimental designC. elegansCre/LoxPFate mapheart developmentheart regenerationmousereporter constructzebrafish

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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

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