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    Bioimage Informatics Activity
    Students use basic bioimage informatics techniques to acquire quantitative data from images of cultured cells and test a hypothesis about the effect of a genetic mutation on cellular phenotypes

    Keywords: geneticsResources @ HHMI - BioInteractivegenomicscancergenetic basis of diseasebiology of cells

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    Cellular Respiration and pH: blocking the electron transport chain and its effects on the proton gradient, pH, and ATP production
    This module contains exercises designed to help students describe the stages of cellular respiration and quantify the energy molecules produced. Students will predict the region of higher proton...

    Keywords: introductory biologyQuantitative reasoningquantitative biologyinterdisciplarycell functionInterpreting GraphsATPpHCellular RespirationEnergy transformationsElectron flowNIQBC2. Data and GraphsC4. mathematical modelsC1. Numeracyproton gradientelectron transportelectron transport blockersFADH2chemiosmosisATP synthaseNADHproton concentration

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    2016-Barbarossa-Kuttler-Mathematical Modeling of Bacteria Communication in Continuous Cultures
    This paper presents a simple system of delay differential equations (DDEs) for quorum sensing of Pseudomonas putida with one positive feedback plus one (delayed) negative feedback mechanism.

    Keywords: gene regulatory networkschemostatbifurcationNumerical Simulationquorum sensing

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    2015-Khan-EtAl-How differential equations influence the tumor growth via mathematical models
    This work demonstrates the importance of differential equations to develop mathematical model of tumor growth.

    Keywords: tumorcancdercancerous cellsimmunotherapymalignant

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    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.

    Keywords: spatialsensitivity analysisgene regulatory networksstochasticbifurcationmetabolic networkselectrophysiologytransductionrate lawsbiochemical reactions

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    A Student-Led Hearing on the Use of HeLa Cells in Research
    In this role-playing case study, students will learn about the HeLa cell line and its origins while examining multiple perspectives surrounding the cell line and its uses. The goal of this case...

    Keywords: bioethicsscience policycell culturedebateHeLa cellsinformed consentrole playsocial justice issues

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    The Science Behind Parthenogenesis: Interesting things happen when meiosis goes “wrong”
    Parthenogenetic reproduction is a fascinating, complex topic.  This article accompanies “Why Meiosis Matters: The case of the fatherless snake.” It summarizes the basic information...

    Keywords: meiosismitosissex determinationAsexual reproductionParthenogenesis

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    Introduction to Genome Browser: What is a Gene?
    In this module, we will use a web-based visualization tool called a Genome Browser to explore the structure of a eukaryotic gene, and obtain a basic understanding of how this information is...
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    A flexible, multi-week approach to plant biology - How will plants respond to higher levels of CO2?
    To help introductory biology students understand how plants will respond to higher levels of CO2, we have created a multi-week module consisting of a series of four related laboratory lessons....

    Keywords: statisticsplantsphotosynthesiscarbon dioxidecommunicating sciencegroup workResource AllocationRespirationStomata

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    Pick Your Poison: A Semester-Long Case Study for Undergraduate Toxicology
    The ability to collate information from diverse scientific resources and effectively employ scientific writing is an essential skill for scientists. This lesson describes a semester-long project...

    Keywords: risk assessmenttoxicologyPharmacologyregulationsdose responseADME

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    Morphological identification of mosquitoes through microscopic observation
    Scientific research is integrated into various stages of student learning, but hands-on involvement in the research process typically begins at the university level. This module aims to engage high...

    Keywords: modulebiologyproject based learningmosquitoScientific researchMicroscope usedigital accessibility

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    SIMIODE Spring 2024 Webinars - WikiModel
    WikiModel is cloud-based application and requires no installation and is run via a web-browser to facilitate rapid implementation. Equations are typed in as they appear in a textbook. ODEs are...

    Keywords: modelingSoftwaretoolapplicationWikiModelmodeling cycle

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    Paleoclimate and Ocean Biogeochemistry (Project EDDIE)
    This module guides students in an examination of how surface ocean productivity relates to global climate on glacial-interglacial timescales and how the availability of ocean nutrients can be...

    Keywords: productivitycarbon cyclebiological pump

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    THE IMPORTANCE OF GREEN SPACES & NATIVE PLANTS TO URBAN AVIFAUNA: A Lesson on how urban residential yards can support birds during their annual cycle
    In this lesson students will learn about the impacts of urbanization, and the conservation challenges it poses to wildlife, in particular avifauna. Introductory ecology topics such as the theory of...

    Keywords: birdsurbanizationPoisson Distributionnative plantsGeneralized linear models

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    6-005-InsectColonySurvivalOpt-ModelingScenario
    We present a system of nonlinear differential equations to model the control of energy flow into producing workers or reproducers in an insect colony, using a set of given parameters and a number...

    Keywords: optimizationOptimal Control Theoryinsect colonyoptimal controlnatural resourcesPointryagin's Maximum Principlecontrol variable

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    2015-Pendrill-Eager-Free fall and harmonic oscillations analyzing trampoline jumps
    In this work, the motion on a trampoline is modelled by assuming a linear relation between force and deflection, giving harmonic oscillations for small amplitudes.

    Keywords: Accelerometersfree falljumptrampoline

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    2011-Lucas_Pulley-Analyzing Predator-Prey Models Using Systems of Ordinary Linear Differential Equations
    This research focused on applying biological mathematics to analyzing predation relationships, especially the relationship between the Canadian Lynx and the Snowshoe Hare.

    Keywords: simulationpredator-preyLotka-VolterrapopulationCanadian LynxSnowshoe Harecritical values

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    2009-Schaffer-Bronnikova-Controlling malaria
    The present paper reviews potential control strategies from the viewpoint of mathematical epidemiology.

    Keywords: epidemiologymalariabifurcationmosquitotransgenic mosquitoes

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    QB@CC: An interdisciplinary network model for developing and disseminating OER to support pedagogical change
    Presentation given at the Northeast OER Summer 2022 We describe the interdisciplinary network that has been developing and sharing quantitative skills-based OER in biological sciences. The...

    Keywords: Resources @ BioQUESTqbccNortheast OER Summit

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    3-055-FloatingBox-ModelingScenario
    In this scenario, we lead students through the process of building a mathematical model for a floating rectangular box that is bobbing up and down.

    Keywords: oscillationArchimedes’ Principlebuoancyoscillatory motionNewton's Second Law

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