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    A simple way for students to visualize cellular respiration: adapting the board game MousetrapTM to model complexity
    Lecture-based introductory biology courses are typically content-heavy as instructors strive to provide students with foundational knowledge in a broad range of topics.  One topic...

    Keywords: ATPGlycolysisCellular RespirationElectron Transport ChainKrebs Cycle

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    Cell Biology by the Numbers
    Vignettes that reveal how numbers serve as a sixth sense to understanding our cells

    Keywords: datacell biologyNumbersratesconcentrationMeasurementestimation

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    Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration
    One key to student success in introductory and cell biology courses is a foundational knowledge of cellular respiration. This is a content area in which students often harbor misconceptions that...

    Keywords: data analysisCellular RespirationElectron Transport ChainEnergy transformationsMitochondriaOxidative phosphorylationWeight loss drugs24-dinitrophenol (DNP)

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    Cell Collective: Computational Modeling and Simulation Designed with the Classroom in Mind
    This working group collaborated on content and pedagogy surrounding the use of Cell Collective to integrate computational modeling and simulation into undergraduate biology curriculum.
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    Meiosis: A Play in Three Acts, Starring DNA Sequence
    Meiosis is well known for being a sticky topic that appears repeatedly in biology curricula. We observe that a typical undergraduate biology major cannot correctly identify haploid and diploid...

    Keywords: recombinationmeiosisDNA sequenceCrossingoverchromosome structureHolliday junctionhomology

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    A STEAM Approach to Investigating the Hydrologic Cycle
    The purpose of this experiential lesson is to teach introductory to mid-level undergraduate students how to make detailed hydrologic field observations into a conceptual model using a painting...

    Keywords: modelinghydrologyfield-based learningSTEAM curriculumhydrogeologyhydrologic cycle

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    Sizes, Scales and Specialization: Adapted to add scientific notation review
    This module explores how cell size and shape varies across cell types in the human body by having students calculate relative proportions of numbers in scientific notation. The adaptation has...

    Keywords: ExponentsRatiosScientific Notationcell typeqbccmanipulate equationsCellular and Molecular Biologyconverting unitschanging scales

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    Sizes, Scales and Specialization: Using Relative Proportions and Scientific Notation to Highlight the Diversity of Cell Types
    This module explores how cell size and shape varies across cell types in the human body by having students calculate relative proportions of numbers in scientific notation.

    Keywords: ExponentsRatiosCellsqbccmanipulate equationsCellular and Molecular BiologyVisual Accommodationsconverting unitschanging scales

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    A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience
    A core competency identified in Vision and Change for undergraduate biology students is the Ability to Apply the Process of Science. Here, we describe a three-week laboratory module for students in...

    Keywords: metacognitiongene expressionScientific ProcessExperimenal DesignHypothesis Generationmodel organisms

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    The Lecture-Free Classroom: Teaching students backward design and Bloom's Taxonomy to create their own learning environment
    We describe Presentation Enhanced Learning (PEL), a flexible, lecture-free, field-tested teaching format to promote problem-based, active learning in upper-division or graduate biological sciences...

    Keywords: active learningbackward designProblem based learningBloom's Taxonomy

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    Sickle Cell Disease and Natural Selection in Humans
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    An Original-Design Board Game to Increase Student Comprehension of Cellular Respiration Pathways
    Cellular respiration is a daunting topic for many students in introductory biology courses. Students are challenged at conceptual and factual levels, since instruction covers multiple metabolic...

    Keywords: GlycolysisCellular RespirationFermentationKrebs CycleOxidative phosphorylationpyruvate oxidation

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    Teaching Cell Structures through Games
    As the basic unit of life, cells are a foundational concept for all of biology. Before students can appreciate how eukaryotic cells function either in isolation or in higher order and multicellular...

    Keywords: Cell Structurecell organellesTransmembrane Transport

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    Sickle Cell Anemia using Nicholas’ Story
    The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...

    Keywords: Hemoglobinsickle cell diseaseMolecular Case Study

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    Using the Cell Engineer/Detective Approach to Explore Cell Structure and Function
    As instructors of introductory biology courses for majors and non-majors, we have struggled with teaching the concept of cell structure and function in an engaging way.  However, this is a...

    Keywords: cell functionCell StructureCellular diversityDynamic cellular functionOrganelle function

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    Sickle Cell Disease Case Study
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    Closing the Gap in the Open Educational Resources (OER) Life Cycle for Using Research Data in the Ecology Classroom
    Poster presented at the 2018 meeting of the Ecological Society of America on gaps in the curriculum cycle for open educational resources (OER) and our work supporting sharing and adaptation of...

    Keywords: OEREcological Society of AmericaDIGoer life cycle

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    Permeability of Molecules
    This module introduces Overton's Rule in the context of understanding the permeability of molecules across the cell membrane. It is intended for an introductory biology audience.

    Keywords: linear regressionPermeabilityCell StructureCell MembraneOpenStaxphospholipid membranelog-log plotsOverton's rule

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    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how...

    Keywords: pathwayscancerMolecular AlterationsRetrospective dataTumorigenesis

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    Discovering Cellular Respiration with Computational Modeling and Simulations
    Cellular respiration, a common topic among introductory and cellular biology curricula, is a complex biological process that exemplifies core biological concepts, including systems, pathways and...

    Keywords: Cellular MechanismsCellular RespirationFermentation

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