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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Using the Cell Engineer/Detective Approach to Explore Cell Structure and Function
    As instructors of introductory biology courses for majors and non-majors, we have struggled with teaching the concept of cell structure and function in an engaging way.  However, this is a...

    Keywords: cell functionCell StructureCellular diversityDynamic cellular functionOrganelle function

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    Sickle Cell Disease Case Study
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    50 Years of Data Science
    This paper reviews some ingredients of the current “Data Science moment”, including recent commentary about data science in the popular media, and about how/whether Data Science is really...

    Keywords: statisticsbig datadata sciencemachine learning

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    Cell Division and the Presence of a Growth Factor
    This module introduces exponential growth, the Michaelis-Menten, and Lineweaver-Burk equations in the context of understanding how growth factors influence cell division. It is intended for an...

    Keywords: exponential equationshyperbolic equationsCell StructureCell Growthgrowth factor

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    Permeability of Molecules
    This module introduces Overton's Rule in the context of understanding the permeability of molecules across the cell membrane. It is intended for an introductory biology audience.

    Keywords: linear regressionPermeabilityCell StructureCell MembraneOpenStaxphospholipid membranelog-log plotsOverton's rule

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    A virtual laboratory on cell division using a publicly-available image database
    Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams....

    Keywords: image analysismicroscopymitosisCellular Processes

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

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    Data Analysis and Cancer
    This is a flipped classroom approach, students will learn the basic content about cell-signaling, p53, and transcription factors before class. During class students will focus on data analysis...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologydata interpretationBiological Data Analysiscell cyclemacromoleculesGenetic diseaseCell signaling

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    Synapse Transmission and Action Potentials
    This module introduces action potentials in the context of understanding nerve impulses. It is intended for an introductory biology audience.

    Keywords: InequalitiesOpenStaxAnimal Physiology

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    BioNumbers-the database of key numbers in molecular and cell biology
    BioNumbers is a database of key numbers in molecular and cell biology—the quantitative properties of biological systems of interest to computational, systems and molecular cell biologists

    Keywords: dataResources @ BioNumbersNumbersestimationdatabaseResources @ QUBES - Teaching & Reference

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    Cell Collective: Learning biology with modeling and simulations
    Cell Collective is an online, research-grade modeling platform adapted to engage students in creating and simulating dynamic models of biological processes.

    Keywords: modelingsimulationSimulationsCell Collective

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    CBEC - Cell Biology Education Consortium (RCN-UBE Introduction)
    The CBEC helps faculty at PUIs move cancer cell culture research into the classroom. The mechanism that provides faculty with the resources they need to do this are modular protocols called Cell...

    Keywords: RCN-UBE Introduction

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    Nucleo-cytoplasmic Transport
    This module introduces exponential decay and the rate of influx in the context of understanding the transport of molecules from the cytoplasm to the nucleus. It is intended for an introductory...

    Keywords: exponential equationsCell StructureCell Growth

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    Spreadsheet Tutorial 2 - Autofill Data, Cell References, and Standard Deviation
    Generate a table with autofill, and use absolute cell reference to calculate variance and standard deviation.

    Keywords: Resources @ HHMI - BioInteractiveScientific ProcessStatistics and MathScientific MethodologyHigh School

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    Targeting Infected Cells for Immune Defense
    This animation shows how a cell infected by a virus signals cytotoxic T cells to destroy itself.

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

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    Diffusion Through a Cell Membrane
    This module introduces rates of diffusion in the context of understanding simple and facilitated diffusion through the cell membrane. It is intended for an introductory biology audience.

    Keywords: linear equationscalculushyperbolic equationsCellular Processesrates of change

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    Quantitative Cytological Characteristics: Photorespiration
    This module introduces quantitative cytological characteristics in the context of understanding cell behavior under stress. It is intended for an introductory biology audience.

    Keywords: plant physiologyRatioschart

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    Wildlife Crossings in Costa Rica: Are wildlife crossing structures effective in mitigating roadkill mortality on tropical highways?
    Meet Jack Ewing, an ecotourism pioneer in Costa Rica who fought to safeguard wildlife from roadkill mortality caused by enlargement of a major highway. This module presents the topic of road...

    Keywords: Biodiversityconservation biologyland use changeRoad Ecologyecosystem managementfragmentation

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    Cell Cycle and Mitosis
    This module introduces activities that allow students to walk through the cell cycle and mitotic cell division processes. As part of the activities, students learn about and apply knowledge of...

    Keywords: introductory biologyQuantitative reasoningInterdisciplinary STEMquantitative biologyinterdisciplinaryquantitative skillscell functioncell cyclemitosisCell DivisionMitotic Indexcalculating meanstumorNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical Analysisstandard errormitotic phaseinterphase

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