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    2015-Heiko_Enderling-Integrating experimental data to calibrate quantitative cancer models
    For quantitative cancer models to be meaningful and interpretable the number of unknown parameters must be kept minimal. We focus on a tumor hierarchy of cancer stem and progenitor non-stem cancer...

    Keywords: cancertumorfittingagent-based

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    Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics
    Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of...

    Keywords: cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

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    Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory
    Traditionally-trained undergraduate students often lack an understanding of science as an active process that yields the information presented in their textbooks. One result has been a call for...

    Keywords: yeastgrowth curvecell proliferationviability

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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs...

    Keywords: fluorescence microscopymitosisCell StructureCell ImagingImmunocytochemistryQuantitative microscopySTEM skills

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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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    Investigating Cell Signaling with Gene Expression Datasets
    Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing...

    Keywords: genomicstranscriptionsignaling

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    Mechanisms of Cell Attachment
    This module introduces the calculation of refractive indices along a cell surface in the context of understanding the attachment of cells to surfaces. It is intended for an introductory biology...

    Keywords: GeometryCell StructureCell GrowthSimple EquationsInterpreting GraphCell Attachment

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    Maintenance of Cell Shape
    This module introduces an equation to calculate roundness in the context of understanding how myosin contributes to cell shape. It is intended for an introductory biology audience.

    Keywords: AlgebraCell StructureCell Growthbar chart

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    Molecular Biology of the Cell (MBoC)
    An online journal focusing upon generally-applicable studies of cell biology.

    Keywords: cell biologycellmolecular biologyResources @ ASCBResources @ QUBES - Teaching & Reference

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    Cell Aggregation and Sphere Packing
    This module introduces the calculation of packing density in the context of understanding cell aggregation and arrangement. It is intended for an introductory biology audience.

    Keywords: RatiosGeometryInequalitiesCell StructureCell GrowthCell AggregationSphere Packing

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    2012-José_Sérgio_Domingues-Gompertz Model - Resolution and Analysis for Tumors
    The main objective of this paper is to use the Gompertz equation in order to study the development of blood irrigated solid tumors, using parameters defined in some important bibliographic...

    Keywords: tumorGompertz equationgrowth tumor

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    Does Organelle Shape Matter? Exploring Cell Shape through the Allen Cell Explorer and High-content Microscopy Datasets
    The morphology and localization of structures inside the cell are often assumed to fit the ideal images found in biology textbooks. This interrupted case study using high-throughput microscopy data...
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    Online Adaptation of the Cell Engineer/Detective Lesson
    One of the most fundamental themes of biology is the relationship between structure and function, which is particularly evident when it comes to cells; however, the traditional cartoon depictions...

    Keywords: cell functionCell StructureOrganelles

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    Cell Division and Rates of Population Growth
    This module introduces the exponential growth of cells in the context of understanding cell division. It is intended for an introductory biology audience.

    Keywords: exponential equationscell growth and divisionGeometric SeriesCell StructureOpenStaxgeometric equations

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    Doubling Time of Tumors
    This module introduces the calculation of potential doubling time of tumorous cells in the context of understanding the growth of a population of the cells. It is intended for an introductory...

    Keywords: linear regressionRatiosCell StructureOpenStaxCell Growth

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    Mitotic Index and Cell Division
    This module introduces the mitotic index in the context of understanding the dynamics of cell division in the root of a plant. It is intended for an introductory biology audience.

    Keywords: RatiosCell StructureCell GrowthchartCell DivisionMitotic Index

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    Cell Biology by the Numbers
    Vignettes that reveal how numbers serve as a sixth sense to understanding our cells

    Keywords: datacell biologyNumbersratesconcentrationMeasurementestimation

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    Cell Collective: Computational Modeling and Simulation Designed with the Classroom in Mind
    This working group collaborated on content and pedagogy surrounding the use of Cell Collective to integrate computational modeling and simulation into undergraduate biology curriculum.
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    Nucleoplasmic Index
    This module introduces the nucleoplasmic index in the context of understanding how the volume of organelles and cell contents change during the cell cycle. It is intended for an introductory...

    Keywords: RatiosInterpreting GraphsCell StructureCell GrowthNucleoplasmic Index

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    Going Remote: An Online Adaptation to Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix
    In light of the COVID-19 pandemic, instructors have modified materials to transition to a remote learning platform. The challenge for science instructors has been to design lab exercises that...

    Keywords: remote learningExtracellular matrixNeural extracellular matrixPerineuronal net

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