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    Calculating Lifetime Cancer Risk Resulting from DNA Replication
    An expanded case study adapted from an HHMI Data Point on Cell Division and Cancer Risk using Figure 1 from Tomasetti, C. and Vogelstein, B. (2015).

    Keywords: cancerScientific ProcessStatistics and MathScientific Methodologybiology of cellscell growth and divisionHigh School

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    Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study
    Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut...

    Keywords: dietanimal behaviorimmune systemmicrobiomeNervous systemgut-brain axisImmunoReachdysbiosisCoyoteCytokines

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    SEAS CURE: Exploring Coral Biology Across Scales
    Complex biological concepts (like symbiosis and coral biology) that span multiple scales and cross disciplinary boundaries are often difficult for students to understand. This complexity is...

    Keywords: microscopyAnatomySymbiosisMetabolismbleachinginvertebratedinoflagellate

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    Sex-specific differences in Meiosis: Real-world applications
    In traditional classrooms, students are typically presented with facts that they are asked to memorize and recall during an exam.  The rapid explosion of available scientific facts in recent...

    Keywords: meiosisReproductionAneuploidyGameteNon-disjunctionOocyteSpermTrisomy

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    Polyploidapalooza: Exploring the diversity and evolution of polyploid plants and animals
    This series of modules explores the complex world of polyploidy, including species formation, cell division, evolution, conservation, and economic importance. We focus on polyploidy across the...

    Keywords: Evolutionconservationnatural historyCell DivisionhybridizationPolyploidygenome duplicationallopolyploidyautopolyploidy

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    The Perfect Brew: An Activity Demonstrating Cell Counting and Hemocytometer Use
    In this activity, students will explore the use of a hemocytometer for counting cells, demonstrate the relationship between the grid seen in the microscope with volume of liquid in suspension and...

    Keywords: RatiosmicrobiologyqbccCellular and Molecular BiologyUnderstanding fractionsconverting unitschanging scalesmeasurements

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    The Perfect Brew: An Activity Demonstrating Cell Counting and Hemocytometer Use
    In this activity, students will explore the use of a hemocytometer for counting cells, demonstrate the relationship between the grid seen in the microscope with volume of liquid in suspension and...

    Keywords: RatiosmicrobiologyqbccCellular and Molecular BiologyUnderstanding fractionsconverting unitschanging scalesmeasurements

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    Joel E. Greengiant Learns About Peas: From Nucleotides to Selection
    This case study follows purveyors of peas, Joel E. and Jolene Greengiant, as they learn about the origin, biochemistry, genetics and eventual artificial selection of sweet (wrinkled) peas, all in...

    Keywords: geneticspopulation geneticsEvolutionintroductory biologycase studybiologyResources @ NSF - NCCSTSmeiosisMendel’s peaspea plantPisum sativumMendel’s Lawsmolecular geneticsmutationnucleotide insertionartificial selectionstarch synthesisstarch branching enzymeplant domesticationlegumesResources @ QUBES - Teaching & Reference

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    A Team-Based Approach to Course Development Involving Undergraduate Researchers
    Development of an undergraduate laboratory course can be a challenge, because of the need to balance both logistical and pedagogical considerations. We piloted a team-based approach to developing...

    Keywords: student researchcourse development

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    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

    Keywords: datatranscriptionvirustranslationprotein functionmembrane transportPredictions

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    Lights, Camera, Acting Transport! Using role-play to teach membrane transport
    Lights, Camera, Acting Transport! is an active and unique role-play exercise designed to teach introductory biology students basic concepts of passive and active membrane transport. The activity...

    Keywords: ATPcarrierschannelsco-transportelectrogenic pumpfacilitated diffusionmembrane transportpassive transportprimary active transportsimple diffusion

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    Using the IEDB to Predict Proteasomal Cleavage Events and T-cell Epitopes
    Research experiences provide a valuable view into the world of science and a great way to explore new fields and careers while developing critical thinking skills. The development and maintenance...

    Keywords: biologydatabaseImmunologydata sciencebioinformaticsBiotechnologyt-cellengineeringantibodyBioengineeringAntibody EngineeringlymphocytesProteinNetChopepitopeIEDBB-cellProteasomeProteasomal Cleavage

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    Modeling the lac Operon to Understand the Regulation of Gene Expression in Prokaryotes
    This resource is a recitation activity designed for an introductory biology course in which students explore a lac operon simulation (https://qubeshub.org/resources/phetlacoperon).

    Keywords: simulationLac Operon

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    Sperm Motility
    This module introduces equations related to oxygen diffusion in the context of understanding the relationship between oxygen needs and metabolism. It is intended for an introductory biology audience.

    Keywords: OpenStaxAnimal Physiologyparabolic equationssquare root

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    A first lesson in mathematical modeling for biologists: Rocs
    Using a fictitious population of Rocs, a mythical species of giant raptor, students accomplish two broad objectives: 1) they undertake the process of building a first mathematical model of a...

    Keywords: population ecologypopulation modelingdiscrete generationpopulation management

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    Applying Universal Design for Learning (UDL) Principles to Case Studies
    This is a presentation for the 2022 BIOME meeting.
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    Cell Collective
    Session presentation on an easy-to-use software, that makes this computational modeling approach accessible to any student and instructor

    Keywords: computational modelSummer Workshop 2018

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    Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts
    Introductory physics courses are required for many programs in the life sciences, yet traditional curricula fail to help students meaningfully connect physical concepts with biological...

    Keywords: quantitative biologyHIVmultiplicity of infectionPoisson DistributionPhysics for biologists

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    From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design
    Engaging first generation underrepresented minority students in the process of inquiry in developmental biology is important to increase diversity in future graduate STEM education. One important...

    Keywords: experimental designC. elegansCre/LoxPFate mapheart developmentheart regenerationmousereporter constructzebrafish

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    Using a Sequential Interpretation of Data in Envelopes (SIDE) approach to identify a mystery TRP channel
    This lesson sought to engage students in data interpretation and to encourage critical thinking about neurophysiology in the context of temperature sensation. A family of receptors called Transient...

    Keywords: Cell communicationChannel specificity and activationLimitations of tools of Cell BiologyNeuronal Signaling

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