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    An Original-Design Board Game to Increase Student Comprehension of Cellular Respiration Pathways
    Cellular respiration is a daunting topic for many students in introductory biology courses. Students are challenged at conceptual and factual levels, since instruction covers multiple metabolic...

    Keywords: GlycolysisCellular RespirationFermentationKrebs CycleOxidative phosphorylationpyruvate oxidation

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    Analysis of Microbiomes Using Free Web-Based Tools in Online and In-Person Undergraduate Science Courses
    Our understanding of microbiomes, or the collection of microorganisms and their genes in a given environment, has been revolutionized by technological and computational advances. However, many...

    Keywords: microbiomeDNA SubwayCyVerseCourse based undergraduate researchQIIME2ranacapa

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    Sexual Dimorphism CURE: Exploring Melanized Wing Patterns of Pieridae Butterflies
    Teach a Course-based Undergraduate Research Experience (CURE) using digitized natural history collections data to test hypotheses on sexually dimorphic wing melanization patterns of Pieris rapae...

    Keywords: data analysismorphologyidigbiosexual dimorphismdata managementImageJsexual selectionnatural history collectionsbutterflycourse-based research experiences (CUREs)digitized natural history collectionsQGISmorphometricsBCEENETgeoreferencing

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    Make Your Move: Interpreting graphs of pollinator behavior
    In this lesson, students interpret graphs of pollinator movement behavior. Then, students view and reflect on an interview with community ecologist Dr. Suann Yang., who collected the data that they...

    Keywords: graph interpretationCommunity EcologyBiodiversitycompetitiondata literacypollinationinvasive plantsinterspecific interactionsBioGraphIrepresentation in STEM#AAPIinSTEM#BIPOCinSTEM

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    Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms
    Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell...

    Keywords: mutationcancertranscriptioncell cycletranslationOncogenesTumor-suppressorp53Transcription factor

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    Sequences and Properties of Gluten Proteins From Different Grains: A Virtual-Friendly Protein Laboratory
    The COVID-19 pandemic has forced much university instruction into virtual modes. As a result, many laboratory courses have either dropped content altogether or replaced hands-on activities with...

    Keywords: protein structure and functionProtein sequenceintermolecular forcesBiomacromolecules

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    Cladistic Analysis Lesson Using Bats
    Phylogenetic analysis can be a challenging concept to grasp for undergraduate biology students. This cladistic analysis lesson utilizes the amazingly diverse Order Chiroptera as a model to...

    Keywords: batsphylogeny and classificationVertebrate Morphologycladistic analysisbat evolution

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    5-010-MatrixExponential-TechniqueNarrative
    The matrix exponential is a powerful computational and conceptual tool for analyzing systems of linear, constant coefficient, ordinary differential equations (ODE's). This narrative offers a quick...

    Keywords: matrix esponentialPutzer's Algorithmdiagonalizationeigenvalueseigenvectors

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    6-020-AlgaePopulationSelf-Replenishment-ModelingScenario
    This modeling scenario investigates the massive algal blooms that struck Lake Chapala, Mexico, in 1994. A

    Keywords: algaepopulationMexicoqualitativecompartmentlinearizationJacobianlaknondimensionalizationpplane

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    A How to Guide and Template for Designing a Puzzle Based Escape Room Game
    Educational games are one active and effective way of engaging students with material while also providing additional motivation to tackle challenging concepts. A particularly popular game concept...

    Keywords: Problem SolvingCollaborative WorkCorrect Misconceptions

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    Interpreting the Pseudocot Phylogeny
    Students use physical characteristics, genetics, and a fossil record of hypothetical flowering plants to develop fundamental phylogenetic tree-building skills.
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    A Student-Led Hearing on the Use of HeLa Cells in Research
    In this role-playing case study, students will learn about the HeLa cell line and its origins while examining multiple perspectives surrounding the cell line and its uses. The goal of this case...

    Keywords: bioethicsscience policycell culturedebateHeLa cellsinformed consentrole playsocial justice issues

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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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    "Got Algae?" A Sorting Game for Introducing the Weird and Wonderful Diversity of Algae
    Algae are a fascinating and diverse organismal group, with global ecological importance, a storied evolutionary history and deep connections to both contemporary and historical human societies. Yet...

    Keywords: phylogenyBiodiversityphotosynthesisalgaeseaweedmonophyly

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    Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix
    The extracellular matrix (ECM) provides structural support to cells, but also has key roles in mediating cell adhesion, cell signaling, and differentiation. While this topic is discussed in the...

    Keywords: Neural extracellular matrixPerineuronal netPrimary neuronal culture

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    Exploring Primary Scientific Literature through the Lens of the 5 Core Concepts of Biology
    Biology students at the undergraduate level usually excel in knowing biological facts; however, they often struggle with connecting these facts to specific biological principles. In parallel,...

    Keywords: 5 core conceptsconnecting facts to principlesreading primary scientific literature

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    Going Remote: An Online Adaptation to Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix
    In light of the COVID-19 pandemic, instructors have modified materials to transition to a remote learning platform. The challenge for science instructors has been to design lab exercises that...

    Keywords: remote learningExtracellular matrixNeural extracellular matrixPerineuronal net

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    A Lesson on Matter and Energy at the Organismal Scale: Linking Patterns and Processes Across Diverse Taxa
    Pathways and transformations of energy and matter (PTEM) are a conceptually challenging but essential component of biological literacy. Curricular gaps about PTEM nevertheless remain; although...

    Keywords: plantsenergyAnimalsfungimatterorganismal scale

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    Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter
    While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division...

    Keywords: DiffusionActive transportfacilitated diffusionNecessary and sufficientTransport proteins

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    The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories
    Inquiry-based undergraduate laboratories provide the opportunity to engage students in a research experience that improves scientific thinking, but such activities can be difficult to develop and...

    Keywords: protein structure and functionhuman genetic variationmuscle physiology

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