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    2009-Su-EtAl-Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS
    In the case of a multiple dose study where subjects experience different dosing times, a superposition principle can be used to recursively account for each additional dose.

    Keywords: SASsuperpositionpharmacokineticscompartmental modelsmultiple dose

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    2009-Reid-King-Pendulum Motion and Differential Equations
    This article presents a relatively simple, real-world example that instructors can use in the classroom to let students explore the effect of simplifying assumptions on a model’s ability to reflect...

    Keywords: pendulumphysical pendulum

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    2009-Noakes-Sleigh-Mathematical models for assessing the role of airflow on the risk of airborne infection in hospital wards
    Understanding the risk of airborne transmission can provide important information for designing safe healthcare environments with an appropriate level of environmental control for mitigating risks.

    Keywords: infectioncompartmenthospitalventilationairbornesthochasticWells–Riley

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    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters...

    Keywords: time seriesEvaluation SPLINEgeneleast squaresbifurcation

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    2007-Zenker-Rubin-Clermont-From inverse problems in mathematical physiology to quantitative differential diagnoses
    The improved capacity to acquire quantitative data in a clinical setting has generally failed to improve outcomes in acutely ill patients, suggesting a need for advances in computer-supported data...

    Keywords: physiologyinverse problem

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    Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website
    Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted...

    Keywords: toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

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    Discovery and Invention: A Reflection on Representation in Science
    Despite increased awareness of the lack of equity and inclusion in the STEMM classroom, lessons on DEI topics are treated as separate to the scientific curriculum being taught. Rarely are...

    Keywords: EquityDiversity and Inclusionantiracism

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    2004-Hill-Lozowski-Sampson-Experiments on ice spikes and a simple growth model
    We observed ice-spike growth using time-lapse digital photography, using two water types in two different containers.

    Keywords: iceice spikebulk heat transfermass conservation

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    Who’s That Speci-Mon? Using PokémonTM to Understand Biological Terminology Using Greek and Latin Roots
    We set out to create a fun and engaging activity using recognizable fictional characters, so students get a chance to practice using Greek and Latin roots to create binomial names. Students in...

    Keywords: linguisticstaxonomyAnatomyGreek and Latin Roots

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    2003-Knorrenschild-Gross-Text Books on Mathematical Modeling in Biology
    Text Books on Mathematical Modeling in Biology Compiled from the Internet by Michael Knorrenschild,

    Keywords: biologyMathematical Biologytextbooktext

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    2016-Rob_deBoer-Population Dynamics  A Graphical Approach
    This book is an introduction into modeling population dynamics in ecology. Because there are several good textbooks on this subject, the book needs a novel ecological niche to justify its existence.

    Keywords: mathematical modelstabilitycompetitionSIRbifurcationconsumptionpopulation population dynamicsgeneral replicationnonlinear density dependenciesfunctional responsepersistencephase plan analysis

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    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.

    Keywords: spatialsensitivity analysisgene regulatory networksstochasticbifurcationmetabolic networkselectrophysiologytransductionrate lawsbiochemical reactions

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    1999-Kowalczyk-Hausknecht-Using DEs To Model Real World Data
    With the increasing availability of easy to use interactive differential equation software, we convinced ourselves to completely redesign the way we teach differential equations.

    Keywords: circuitTorricelli's LawHooke's LawRC circuitharmonic oscillatorglucoseglucose tolerance test

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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not...

    Keywords: sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search

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    Concept mapping exercise for ecological news story and peer feedback
    This activity is designed for small groups to work together in class to create a concept map based upon an ecological news story. Any short news story can be selected. One is provided here, along...

    Keywords: ecologysystems thinkingconcept mappingpeer feedbackin-class exercise

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    Species Conservation Management Plan Report and Class Exercise
    In this project, students work in pairs to become an expert in their assigned IUCN Red List endangered species. They are charged to create a well-researched, written conservation management plan....

    Keywords: ecologyconservation4DEE Frameworkmanagement planspeed dating exercise

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    Integrating the modeling of biogeochemical cycles and energy flow
    This in-class activity challenges students to create and then integrate models of how carbon, nitrogen, water and energy all move within an ecosystem. Using 15 provided standard pools, they work...

    Keywords: modelingecologyintegration4DEE FrameworkBiogeochemical cycles

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    Applying ESA’s 4DEE framework to guide the development of ecological literacy for non-majors
    The Four-Dimensional Ecological Education (4DEE) framework, endorsed by the ESA Governing Board in November 2018, is the culmination of 30 years of work by the ecology community to clearly define...

    Keywords: ecology4DEE Frameworkecological literacy

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    A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity
    The distinction between very polar and less polar substances is a foundation of biochemistry, cell biology, and physiology; it surfaces in multiple concept inventories and elaborations of...

    Keywords: Diffusionsolubilitycovalent bondshydrophilichydrophobicpartition coefficientplasma membranepolarity

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    1999-Peter_Deuflhard-Differential Equations in Technology and Medicine
    It deals with a variety of challenging real life problems selected from clinical cancer therapy, communication technology, polymer production, and pharmaceutical drug design.

    Keywords: cancerdesigntumordrugpolymertherapy

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