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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression.  This laboratory lesson allows students...

    Keywords: bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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    IBP - Preparing to Prepare the 21st Century Biology Student: Using Scientific Societies as Change Agents for the Introductory Biology Experience (RCN-UBE Introduction)
    This was the first or second RCN-UBE award made. The Introductory Biology Project (IBP) collaborated with the National Association of Biology Teachers (NABT) to link introductory biology...

    Keywords: RCN-UBE Introduction

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    A CRISPR/Cas Guide RNA Design In Silico Activity
    CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become...

    Keywords: bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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    Intro to BIOMAAP - Student Math Anxiety Overview - Teaching Notes - Boersma
    Teaching notes from my application of the BIOMAAP math anxiety materials in my BIOL305 Ecology course for biology majors.

    Keywords: ecologymath attitudesResources @ BIOMAAP

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    Avida-ED
    Avida-ED is an award-winning educational application developed at Michigan State University for undergraduate biology courses to help students learn about evolution and scientific method.

    Keywords: simulationEvolutionbiologyscientific methodResources @ QUBES - Softwaredigitalhypotheses

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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    A virtual laboratory on cell division using a publicly-available image database
    Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams....

    Keywords: image analysismicroscopymitosisCellular Processes

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    A new approach to course-based research using a hermit crab-hydrozoan symbiosis
    There are few feasible models for marine-focused inquiry laboratory activities, a notable shortcoming for instructors seeking to engage their students in meaningful, course-based research...

    Keywords: behaviorparasitismSymbiosismutualismcommensalism

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    2008-William_Revelle-Cues Tendencies and Actions-The Dynamics of Action Revisited
    This article describes a reparameterization of the original theory of dynamics of action and applies the power of simple modeling to the study of action, emotions, and social behavior.

    Keywords: psychologytask referenceachievement motivationdynamics of action

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    2007-Bellomo-De_Angelis-Delitala-Lecture Notes on Mathematical Modelling in Applied Sciences
    The Lectures Notes correspond to the first part of the course devoted to modelling issues to show how the application of models to describe real world phenomena generates mathematical problems to...

    Keywords: spring massLegendre polynomialsintegro-differential equationskinetic theory

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    5-010-MatrixExponential-TechniqueNarrative
    The matrix exponential is a powerful computational and conceptual tool for analyzing systems of linear, constant coefficient, ordinary differential equations (ODE's). This narrative offers a quick...

    Keywords: matrix esponentialPutzer's Algorithmdiagonalizationeigenvalueseigenvectors

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    2-005-LinearizeItAll-TechniqueNarrative
    Linear approximations are often used to simplify nonlinear ordinary differential equations (ODEs) for ease in analysis. The resulting linear approximation produces an ODE where closed form...

    Keywords: computationerrorTorricelli's Lawdata fittinglinear approximation

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    Ecological Forecasting Student Resource: Overview of Forecasting, Potential Careers, Helpful Courses
    Are you an undergraduate or graduate student interested in learning more about ecological forecasting? Or do you work with students that are exploring career options? This is short resource...
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    The Human Microbiome Biodiversity in Health and Disease
    The students will analyze the human gut and vaginal microbiomes in healthy and diseased states using diversity of bacteria as determined by 16SrRNA sequence.
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    Yeti or not: Do they exist?
    Through this 4-part bioinformatics case study, students will be led through the forensic analysis of putative Yeti artifacts based on published findings.

    Keywords: case studybioinformaticsNIBLSEBLAST12S sequencingYeti

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    Discrete Modeling and Structures (Course Materials)
    These are the materials for DCS course offered at Bates College. This is a sampler of structures and ways they are used to model biological and social phenomena.

    Keywords: labsagent-based modelingoctavematlabDiscrete Difference Equationsmatrix modelscoursezombiesbiomath courseeconomicsdemonstrationin-class activitylab protocolproblem sethamlet

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    Marriage Model (with errors)
    Marriage age model for use with NetLogo and ABM material

    Keywords: computational modelagent-based modelsocial networksmarriageChapter 6Chapter 6.5

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    Using DNA Subway to Analyze Sequence Relationships
    This is a bioinformatics exercise using the DNA Subway Blue Line, a user-friendly pipeline of bioinformatics tools, to analyze a collection of mosquito DNA bar-code sequences.

    Keywords: phylogeneticsNIBLSEDNA BarcodingDNA sequenceBLASTmultiple sequence alignmentC1. Role of bioinformaticsC2. Computational conceptsC4. Bioinformatics toolsC5. Data retrievalC8. Data typesIncubated at NIBLSE

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    Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience
    Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience...

    Keywords: EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

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    You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”
    With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented...

    Keywords: bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)

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