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    2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.

    Keywords: kineticsSAScompartmentpharmacokinetics

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    1996-D_Erdman-MM_Morelock-A Study of Kinetics
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.

    Keywords: simulationkineticsparameter estimationEnzymesubstratesavingscompartmentstomachbloodginseng

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    1-115-ModelingWithFirstOrderODEs-ModelingScenario
    Several models using first order differential equations are offered with some questions on formulating a differential equations model with solutions provided.

    Keywords: bacteriafalling objectNewton's Law of Coolingdrugcoolingdrag

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    3-027-BobbingDropping-ModelingScenario
    We present two exercises in which we ask students to model (1) falling object experiencing terminal velocity and (2) bobbing block of wood in liquid. We model the motion using Newton's Second Law...

    Keywords: drug resistancedirectedbuoyancyfree fallstatic equilibriumdisplacement

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    Discrete Math Modeling with Biological Applications (Course Materials)
    These are the materials for Math 214 offered at Rhodes College.

    Keywords: labsagent-based modelingDiscrete Difference Equationsmatrix modelscoursebiomath coursedemonstrationin-class activitylab protocolproblem set

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    Regulation of Gene Expression and Adipogenesis by PPAR-γ
    Students learn about transcriptional regulation of PPAR-γ, an important controller of adipose tissue stores and energy metabolism through a drawing/coloring activity of the different components...

    Keywords: gene expressionsmall group worktranscriptional regulationadipose tissuefat metabolismrepressor

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    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

    Keywords: datatranscriptionvirustranslationprotein functionmembrane transportPredictions

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    2017-David_Morin-Oscillations
    So needless to say, an understanding of oscillations is required for an understanding of waves.

    Keywords: dampingfrequency responseresonanceoscillationbeatsunderdampingharmonic oscillatorsover dampingcritical damping

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    Antibiotic Resistance Genes Detection in Environmental Samples
    Our aim is to provide an authentic research experience for undergraduate students in a variety of biology courses through collaboration between a four-year university and a community college. This...

    Keywords: geneticsenvironmentmicrobiologyUndergraduateantibiotic-resistancePCRgel electrophoresisauthentic inquiry

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    Cold blood and wet skin in hot and dry secondary forests. How do amphibian traits determine persistence in secondary forests?
    Students will synthesize information from biological and physiological traits of amphibians and characteristics of secondary forests in the tropics to form hypotheses about persistence of...

    Keywords: life historyconservation biologyphysiological ecologyamphibianland use changeEctothermsecondary foresttrait-based ecology

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    2015-Boggess-EtAl-Mathematical Modeling in Ecology - Simulating the Reintroduction of the Extinct Passenger Pigeon
    To determine under which conditions a Passenger Pigeon could survive a reintroduction into a natural habitat, we used two types of models.

    Keywords: simulationagent-based modelingallee_effectPassenger Pigeonsforest envirnomentHolling Type III functional responseBio-energeticstree distributions

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    2018-Weber_Theers_Surmann_Ligges_Weihs-Sensitivity Analysis_of_Ordinary_Differential_Equation_Models
    This report will focus on the sensitivity analysis of ordinary differential equation (ODE) models since they can be used to model so-called Low Frequency Oscillations (LFOs).

    Keywords: sensitivityregressionparameter estimationsystemlow frequency oscillationsoscillations

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    4-023-MysteryCircuit-ModelingScenario
    Students to build a system of differential equations which model a circuit. We give each student a unique input voltage frequency parameter and ask for system response (gain) to that input as a...

    Keywords: filterscircuitRLC circuitKirchhoffvoltagegaindriver

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    Climate-Induced Shifts in California Butterflies
    A module in which students generate and test hypotheses about butterfly species’ response to climate change in the Central Valley and Sierra Nevada Mountains of northern California using publicly...

    Keywords: linear regressionScatter Plotsclimate changephenologyhypothesis formulationmountainsCaliforniapublic dataCODAP

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    The Insect Predation Game
    Laboratory experiment included in Teaching Issues and Experiments in Ecology (TIEE) Volume 4 The main learning objective of this module was to tie together what students had learned during the...

    Keywords: simulationpredator-preypredation ecology

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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    2012-Augustus-Wali-Mathematical Modeling of Uganda Population Growth
    The purpose of this paper focuses on the application of logistic equation to model the population growth of Uganda using data from 1980 to 2010 (inclusive).

    Keywords: population growthlogistic growthDrug and Alcohol detoxificationcarrying capacityvital coefficients

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    2009-Su-EtAl-Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS
    In the case of a multiple dose study where subjects experience different dosing times, a superposition principle can be used to recursively account for each additional dose.

    Keywords: SASsuperpositionpharmacokineticscompartmental modelsmultiple dose

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    2002-Patrick_Nelson-Alan_Perelson-Mathematical_analysis_of_delay_differential _equation_models_of_HIV-1_infection
    Models of HIV-1 infection that include intracellular delays are more accurate representations of the biology and change the estimated values of kinetic parameters when compared to models without...

    Keywords: delayHIV-1T cellscombination antiviral therapy

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    The Lecture-Free Classroom: Teaching students backward design and Bloom's Taxonomy to create their own learning environment
    We describe Presentation Enhanced Learning (PEL), a flexible, lecture-free, field-tested teaching format to promote problem-based, active learning in upper-division or graduate biological sciences...

    Keywords: active learningbackward designProblem based learningBloom's Taxonomy

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