You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    Maria vs Malaria
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria.

    Keywords: bioinformaticsmolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

    413

    views

    265

    downloads

    0

    comments

    1

    adaptations

    2015-G_Knott-Chemical Kinetics - Simple Binding F + G to and from B
    The study of this reaction, F + G goes to and from B, is common in chemistry and biochemistry. For example, F could be a hormone or drug and G the associated receptor sites.

    Keywords: bindingreactionchemical kineticsdeterministicBiochem Labsprobabilistickinetic reaction

    91

    views

    70

    downloads

    0

    comments

    0

    adaptations

    1994-S_S_Everingham-C_Peter_Rydell-Modeling the Demand for Cocaine
    This is a report prepared for the Office of National Drug Control Policy of the United States Army by the Rand Corporation. The report contains lots of data and builds a two compartment difference...

    Keywords: drugstwo compartmentcocainedemand

    84

    views

    36

    downloads

    0

    comments

    0

    adaptations

    1964-Aghajanian-Bing-Persistence Of LSD In Plasma In Human Subjects
    Two micrograms per kilogram of LSD-25 was administered intravenously to five normal human subjects. The concentration of[ drug in plasma was determined serially over the subsequent 8 hours. We...

    Keywords: LSDscoreplasmalysergic acid diethylamidehuman subjuects

    143

    views

    60

    downloads

    0

    comments

    0

    adaptations

    Studying disease with Dr. Ameeta Parekh of the FDA
    Ameeta Parekh, Ph.D. is the Senior Advisor for Scientific Collaborations in the Office of Translational Sciences for the FDA. She talked to us about the FDA's mission and purpose, an overview of...

    Keywords: diseasedrugsregulatory complianceFDA

    381

    views

    75

    downloads

    0

    comments

    0

    adaptations

    A discussion of C-Path, regulation science, and recommended drug treatments with Nicholas King
    Nicholas King acts as the Scientific Program Manager for the Critical Path (C-Path) Institute’s Biomarker Program. He discusses the journey he has been on to arrive at his position, what the...

    Keywords: healthCollaborative researchdrug discovery

    635

    views

    109

    downloads

    0

    comments

    0

    adaptations

    Drug screening and cancer resistance: EGFR Activity
    This activity explores a specific gene (egfr) and its role in cancer. EGFR was introduced with the Gene Card Activities, researched throughout the semester, and then authentic image data of...

    Keywords: Resources @ HHMI - BioInteractivegenomicscancergenetic basis of diseasebiology of cells

    1284

    views

    1395

    downloads

    0

    comments

    0

    adaptations

    Harnessing the Power of the Immune System: Influenza Vaccines
    Because most people have been infected by and/or immunized against influenza, students should know how the immune system responds to the infection and how vaccines protect against disease. Vaccines...

    Keywords: VaccinesInfluenzaImmunizationVaccine efficacy

    2488

    views

    472

    downloads

    0

    comments

    0

    adaptations

    2019-Fred_Brauer-The_Final_Size_of_a_Serious_Epidemic
    In an epidemic of a serious disease, there is likely to be behavioral response that decreases the epidemic size considerably.

    Keywords: epidemicfinal sizebehavioral responseSIER modelrelations

    90

    views

    30

    downloads

    0

    comments

    0

    adaptations

    Type II Functional Response: Holling’s Disk Equation
    This module introduces the Holling’s disk equation in the context of understanding the relationship between an individual's rate of consumption and food density. It is intended for an introductory...

    Keywords: ecologyHolling's Disk Equation

    867

    views

    157

    downloads

    0

    comments

    0

    adaptations

    Understanding Gastric Acid Secretion: An Active Learning Approach
    The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the...

    Keywords: diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit

    1080

    views

    528

    downloads

    0

    comments

    0

    adaptations

    5-011-ModelingIbuprofren-ModelingScenario
    We consider modeling of data from a clinical experiment administered as oral doses of 400 mg ibuprofen, an analgesic pain reliever. Concentrations of ibuprofen in the serum/plasma of the subjects...

    Keywords: dataAICAkaike Information Criterionabsorptionsum of square errorscompartment modelibuprofendelay

    538

    views

    297

    downloads

    0

    comments

    0

    adaptations

    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

    1157

    views

    484

    downloads

    0

    comments

    0

    adaptations

    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

    1600

    views

    506

    downloads

    0

    comments

    4

    adaptations

    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

    6321

    views

    1582

    downloads

    0

    comments

    0

    adaptations

    Antibody Binding
    This module introduces the Scatchard equation in the context of understanding antigen binding and the properties of antigens. It is intended for an introductory biology audience.

    Keywords: linear equationshyperbolic equationsCellular Processes

    1193

    views

    191

    downloads

    0

    comments

    0

    adaptations

    2014-Vance-Eads-Sensitivity Analysis of a Three-Species Nonlinear Response Omnivory Model with Predator Stage Structure
    We investigate a three-species nonlinear response omnivory model incorporating stage structure in the top predator. The model consists of four coupled ordinary differential equations involving...

    Keywords: stage structuresensitivity analysismortalityomnivoreomnivory modelsearch rates

    186

    views

    58

    downloads

    0

    comments

    0

    adaptations

    2016-Roberto_Camporesi-A fresh look at linear ordinary differential equations with constant coefficients
    We present an approach to the impulsive response method for solving linear constant-coefficient ordinary differential equations of any order based on the factorization of the differential operator.

    Keywords: impulseGreen functionsinstructional exposition

    112

    views

    55

    downloads

    0

    comments

    0

    adaptations

    Nastic Movements in Plants
    This module introduces an osmotic model in the context of understanding plants' capability of rapidly adapting to changes in their environment. It is intended for an introductory biology audience.

    Keywords: plant physiologyhyperbolic equationsOpenStaxinterpreting modelsnastic movements

    1036

    views

    311

    downloads

    0

    comments

    0

    adaptations

    2017-Fred_Adler-Mathematically Modeling Asthma
    Our Asthma models have examined how a viral infection can tip the immune system into a different state, with the potential to predispose an individual to future asthma

    Keywords: infectionasthmaimmune responserhinovirus

    117

    views

    66

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search