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    2017-D_Goulet-Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments
    In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The differential...

    Keywords: optimizationBiochemistrysensitivity analysischromatographymass actioncluster analysisconservation lawsdimerizationestrogen receptor protein

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    2016-Lofgren-EtAl-Equations of the End Teaching Mathematical Modeling Using the Zombie Apocalypse
    In this article, we explore several uses of zombie epidemics to make mathematical modeling and infectious disease epidemiology more accessible to public health professionals, students, and the...

    Keywords: simulationinfectious diseasediseaseepidemicZombieWhite Zed

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    2016-Lewnard-Townsend-Climatic and evolutionary drivers of phase shifts in the plague epidemics of colonial India
    Our analysis shows that historical datasets can yield powerful insights into the transmission dynamics of reemerging disease agents with which we have limited contemporary experience to guide...

    Keywords: infectious diseasepVector-Borne Diseaselagueplague

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    2016-Barbarossa-Kuttler-Mathematical Modeling of Bacteria Communication in Continuous Cultures
    This paper presents a simple system of delay differential equations (DDEs) for quorum sensing of Pseudomonas putida with one positive feedback plus one (delayed) negative feedback mechanism.

    Keywords: gene regulatory networkschemostatbifurcationNumerical Simulationquorum sensing

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    2015-The European Bioinformatics Institute-BioModels Database
    BioModels Database is a repository of computational models of biological processes. Models described from literature are manually curated and enriched with cross-references.

    Keywords: computational biologyBioModels Databasebio databaselife science experiments

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    2015-Dios-EtAl-How Engineers deal with Mathematics solving Differential Equations
    The students of fourth course, of the bachelor’s degree in Computer Sciences or Industrial Engineering at the University of Salamanca (Spain), they learn mathematics solving real problems with the...

    Keywords: assessmentengineering educationSimulink

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    2014-Michael_Monagan-The Mortgage Payment Problem Approximating a Discrete Process with a Differential Equation
    In this article and a subsequent article I will give two non-standard examples that I've found helpful. The one presented here is a first order linear system. Second order systems and non-linear...

    Keywords: compartmentheatinghouse

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    2013-Alicia_Caldwell-Students Rise to the Challenge of Modeling Yeast Growth Despite Sour Hiccups from Imperfect Data
    This paper describes a lab in which students in an Applied Mathematics in Biology course observe the growth of Saccharomyces cerevisiae, a yeast strain, in differing sugar concentrations for use in...

    Keywords: Saccharomyces cerevisiaelogisticyeastdeathgrowthsugaralcohol

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    2012-Transtrum-Qiu-Optimal experiment selection for parameter estimation in biological differential equation models
    We explore the question to what extent parameters can be efficiently estimated by appropriate experimental selection.

    Keywords: experimental designsystems biologyAssociation & Data Fittingreaction ratesdecay rates

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    RAT ATTACK! Population growth
    This module contains exercises focused on the use and interpretation of density independent and density dependent population growth models. Students build logistic and exponential growth models in...

    Keywords: modelingecologyExcelintroductory biologygraphingQuantitative reasoningdata visualizationinterdisciplinaryexponential growthlogistic growthdata managementInterpreting Graphspopulation modelingNIQBC2. Data and GraphsC4. mathematical modelsnonlinear models

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    2011-Nancy_Rodrıguez-Applied Partial Differential Equations in Crime Modeling and Biological Aggregation
    In the first part we study a fully-parabolic system of PDEs for residential burglary ‘hotspots’ (spatio-temporal areas of high density of crime). In this work we are concerned with the existence...

    Keywords: biologyDiffusionKeller-Segel modelchemotaxiscrime

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    2011-Mandal-EtAl-Mathematical models of malaria
    The first aim of this article is to develop, starting from the basic models, a hierarchical structure of a range of deterministic models of different levels of complexity. The second is to...

    Keywords: epidemiologytransmissionhost-parasitemalariaRoss model

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    2011-Lucas_Pulley-Analyzing Predator-Prey Models Using Systems of Ordinary Linear Differential Equations
    This research focused on applying biological mathematics to analyzing predation relationships, especially the relationship between the Canadian Lynx and the Snowshoe Hare.

    Keywords: simulationpredator-preyLotka-VolterrapopulationCanadian LynxSnowshoe Harecritical values

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    2011-GA_Koch-Noble-Drugs in the Classroom Using Pharmacokinetics to Introduce Biomathematical Modeling
    By beginning with simple model involving the half-life of a drug, students take advantage of their mathematical abilities to explore the biology.

    Keywords: Biomathematicspharmacokinetics

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    2010-Roberto_Munoz-Alicea-Mathematical Model for Enzyme Kinetics-Multiple Timescales Analysis
    We study a basic model for enzyme substrate reaction. Through several assumptions and via nondimensionalization, we simplify the equations.

    Keywords: kineticsEnzymesubstratenondimensionalizationmultiple timescales

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    2010-Jungck-EtAl-Mathematical Manipulative Models-In Defense of Beanbag Biology
    This paper offers up samples of projects from the Bio- QUEST Curriculum Consortium’s 24-yr experience of holding faculty development workshops for biology and mathematics educators.

    Keywords: epidemiologysimulationinfectious diseasedisease transmissiondiseasein-class activitybean bag activity

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    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters...

    Keywords: time seriesEvaluation SPLINEgeneleast squaresbifurcation

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    Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website
    Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted...

    Keywords: toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

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    2007-I-Liang_Chern-Mathematical Modeling and Differential Equations
    In this course, I will mainly focus on, but not limited to, two important classes of mathematical models by ordinary differential equations: • population dynamics in biology • dynamics in...

    Keywords: population dynamicsecologydynamicsclassical mechanicschemical reaction

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    2006-Wilensky-Reisman-Thinking Like a Wolf a Sheep or a Firefly
    We describe a computation-based approach that enables students to investigate the connections between different biological levels using agent-based, embodied modeling tools.

    Keywords: simulationNetLogopredator-preyagent-basedwolffox

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