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    2015-Heiko_Enderling-Integrating experimental data to calibrate quantitative cancer models
    For quantitative cancer models to be meaningful and interpretable the number of unknown parameters must be kept minimal. We focus on a tumor hierarchy of cancer stem and progenitor non-stem cancer...

    Keywords: cancertumorfittingagent-based

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    9-020-HeatDiffusion-ModelingScenario
    This project guides students through experimental, analytical, and numerical techniques for understanding the heat (diffusion) equation with nonhomogeneous boundary conditions. In particular,...

    Keywords: laboratoryDiffusionheat

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    2012-Transtrum-Qiu-Optimal experiment selection for parameter estimation in biological differential equation models
    We explore the question to what extent parameters can be efficiently estimated by appropriate experimental selection.

    Keywords: experimental designsystems biologyAssociation & Data Fittingreaction ratesdecay rates

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    RNAseq data analysis using Galaxy
    This is a bioinformatics exercise intended for use in a computer lab setting with life science majors.

    Keywords: LabbioinformaticsNCBImappingUndergraduateworkflowNIBLSEGalaxyRNAseqgene expressionAdvancedExtended ProjectArabidopsisC1. Role of bioinformaticsC2. Computational conceptsC3. Statistical conceptsC5. Data retrievalIncubated at NIBLSEdifferentially expressed genes

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    1935 GFGause Article Predator Prey Oscillations
    N/A

    Keywords: Lotka-Volterrapredatorparameciumpreycycleoscillate

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    Maintenance of Phenotypic Polymorphism and a Scientist Spotlight Featuring Dr. Swanne Gordon
    In this lesson students interpret graphical evidence of frequency-dependent selection in the wood tiger moth, then make long-term evolutionary predictions. They then read and reflect on an...
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    2007-Helfgott-Seier-Some Mathematical and Statistical Aspects of Enzyme Kinetics
    We will analyze some basic ideas behind enzyme kinetics, which allow us to deal with separable and linear differential equations as well as realize the need to use power series.

    Keywords: kineticsEnzymeexperimental dataregresion

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    Modeling the Research Process: Authentic human physiology research in a large non-majors course
    Laboratory experiences in large-enrollment introductory science courses often utilize “cookie-cutter style” laboratory experiences due to the relative simplicity of setting up the lab...

    Keywords: data analysishypothesis testingexperimental designphysiology

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    Statistics for Biologists
    There is no disputing the importance of statistical analysis in biological research, but too often it is considered only after an experiment is completed, when it may be too late.

    Keywords: statisticsdata analysisexperimental design

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    REMNet Tutorial, R Part 5: Normalizing Microbiome Data in R 5.2.19
    Video on normalizing microbiome data from the Research Experiences in Microbiomes Network

    Keywords: geneticsstatisticsdata analysisgraphingRStudioVideoexperimental designR programming languagemicrobiomesstudent researchinterdisciplinary educationlimnologyeco-informaticsresearch in the classroomtidyverseWorking with datasetsREMNet

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    Quantifying Uncertainty and Distinguishing Data Sets in Introductory Physics
    Physics labs are moving increasingly to open-ended experiments where students develop experimental physics skills, rather than verify textbook physics concepts. This sequence of activities sets the...

    Keywords: statisticsMeasurementlaboratoryuncertaintypendulumexperimental skills

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    RNA-seq Analysis
    In this computer lab module, students learn how to process an RNA-seq data set to identify differentially expressed genes (DEGs). The samples for this data set were collected from yeast cells...

    Keywords: LabRNAsequencingUndergraduateNIBLSEincubatorsRNAseqInstructional SettingAudience LevelActivity LengthMore than 1 hourC4. Bioinformatics toolsC5. Data retrievalReviewed at NIBLSEdifferentially expressed genes

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    2017-D_Goulet-Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments
    In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The differential...

    Keywords: optimizationBiochemistrysensitivity analysischromatographymass actioncluster analysisconservation lawsdimerizationestrogen receptor protein

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    3-099-PullBack-ModelingScenario
    We guide students through the development of an empirical model for the velocity and distance traveled of a simple pull-back toy. Students can record videos and extract data using their own...

    Keywords: dynamicspull-back toy

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    Food Chain Dynamics In A Simple Ecosystem
    In this lab, students will work with a simple algae/brine shrimp environment to learn about food chains and population dynamics. It was implemented with limited alteration for an Introductory...

    Keywords: ecologyecosystemsfood chain

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    Developing quantitative skills for ecological data: the effects of climate warming on phenological variation and species interactions
    Students combine long-term observational data sets and experimental warming in an alpine meadow in Gothic, CO to test, evaluate, and interpret ecological data focusing on phenological variation and...

    Keywords: species interactionsclimate changequantitative skillsphenologyenvironmental variationphenological mis-match

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    9-125-BeamModeling-ModelingScenario
    This modeling scenario examines the deflection of a cantilever beam under two different distributed loads. Students will have the opportunity to conduct experiments with their own cantilever beam...

    Keywords: Fluid MechanicsbeamcantileverimpulseLaplace transformboundary conditionfourth order

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    1980-Peastrel-Lynch-Armenti-Terminal velocity of a shuttlecock in vertical fall
    We have performed a straightforward vertical fall experiment for a case where the effects of air resistance are important and directly measurable.

    Keywords: fallingterminal velocityshuttlecockvertical fall

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    GEA Introductory lesson on RNA-Seq
    This RNA-Seq lesson uses the CyVerse VICE Platform and Jupyter notebooks to examine the expression of the leptin gene in samples from a mouse experimental design evaluating diet (high-fat vs....

    Keywords: data sciencebioinformaticsGenome BrowserRNAseqhigh throughput sequencingmRNAAlignmentNCBI Sequence Read Archive

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    3-069-HeatInBar-ModelingScenario
    The temperature distribution along a uniform slender bar due to conduction and convection is investigated through experimental, analytical, and numerical approaches.

    Keywords: heat transferexperimentconductionconvectionboundary conditionsfinite volume method

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