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    The Science Behind the ACTN3 Polymorphism
    A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has...

    Keywords: protein structure and functionhuman genetic variationskeletal muscle physiology

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    Sequences and Properties of Gluten Proteins From Different Grains: A Virtual-Friendly Protein Laboratory
    The COVID-19 pandemic has forced much university instruction into virtual modes. As a result, many laboratory courses have either dropped content altogether or replaced hands-on activities with...

    Keywords: protein structure and functionProtein sequenceintermolecular forcesBiomacromolecules

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently...

    Keywords: modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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    Problem-Based Learning for Physiology: Synthesizing the Cardiovascular System, Respiration, Macronutrient Metabolism, and Renal Function
    Problem Based Learning (PBL) is a valuable tool for helping students overcome reliance on memorization by scaffolding opportunities for them to practice the competency of...

    Keywords: MetabolismObesityblood pressurecardiac functioncardiovascularmetabolic syndromerenalRespirationrespiratory system

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    Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation
    Success in biochemistry and other life science courses requires that students understand important biological concepts. One of these concepts is how gene regulation ensures that homeostasis is...

    Keywords: gene regulationinducible operonProkaryotic cellPhosphoenolpyruvate transferase system (PTS)

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    Cell Cycle and Mitosis
    This module introduces activities that allow students to walk through the cell cycle and mitotic cell division processes. As part of the activities, students learn about and apply knowledge of...

    Keywords: introductory biologyQuantitative reasoningInterdisciplinary STEMquantitative biologyinterdisciplinaryquantitative skillscell functioncell cyclemitosisCell DivisionMitotic Indexcalculating meanstumorNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical Analysisstandard errormitotic phaseinterphase

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    Implementing an online module about measuring carbon stocks in an undergraduate Earth Science course
    In this implementation of a case study in which high technology was used to measure carbon stocks in a tropical forest, earth science students in this 4-year college in Oklahoma applied concepts...

    Keywords: climate changephotosynthesisbiomasscarbon cyclegreenhouse gas effect

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    High technology to measure forest carbon stocks: How can advanced remote sensing improve biomass quantification in the Brazilian Amazon?
    A case study on the estimation of aboveground biomass using advanced remote sensors (LiDAR and hyperspectral) in the Brazilian Amazon. Students explore remote sensing (RS) data and compare RS-based...

    Keywords: climate changeremote sensinghyperspectraltropical forestsLiDAR data analysiscarbon stocks

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    Restoring Tropical Forests: Implementing an online module in an undergraduate biology course in Indonesia
    This resource describes my implementation of a module on tropical forest restoration in Costa Rica for an undergraduate Ecology course at Universitas Gadjah Mada, Indonesia....

    Keywords: RestorationEcosystem Servicesforest restorationtransdisciplinary researchsocial forestryhuman well-beingcommunity-based

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    Restoring tropical forests: Implementing an online module about restoration and succession in an advanced undergraduate ecology course
    “Restoring tropical forests” was implemented, using restoration as an example of variation in successional pathways, in an undergraduate course at Arizona State University. New versions of the...

    Keywords: resourcesimplementationRestorationtropical forestssuccession

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    2016-Erno_Keszei-Chemical Kinetics for Beginners
    The most important goal of kinetic research is the identification and characterisation of elementary molecular events which make possible the transformation of reactants into products.

    Keywords: kineticszeroth order reactionfirst order reactionsecond order reactionreaction ratesthird order reaction

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    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics...

    Keywords: longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics

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    2008-Chernyshov-EtAl-The Problem of Modelling of Economic Dynamics in Differential Form
    The authors have tried to analyze procedures of the construction of differential equations that are employed for modeling of macroeconomic processes. The results prove to be rather unexpected.

    Keywords: Fredholm integral equation ofLeontief’s modelmacroeconomic processes

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    2007-Zenker-Rubin-Clermont-From inverse problems in mathematical physiology to quantitative differential diagnoses
    The improved capacity to acquire quantitative data in a clinical setting has generally failed to improve outcomes in acutely ill patients, suggesting a need for advances in computer-supported data...

    Keywords: physiologyinverse problem

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    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important...

    Keywords: paracetamolpharmacokineticsstomachsmall intestinesulfapyridine

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    1984-Marguerite_Hays-Compartmental Models for Human Iodine Metabolism
    Compartmental models for the various aspects of human iodine metabolism are reviewed, emphasizing the role of Mones Berman in the development of this field.

    Keywords: compartment modeliodinethyroid

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    1980-Peastrel-Lynch-Armenti-Terminal_velocity_of_a_shuttlecock_in_vertical_fall
    This paper offers a set of data on a falling shuttlecock (the moving object in badminton) in air. How the authors collected the data is described fully and can be replicated easily by modern...

    Keywords: parameter estimationdata collectionresistancefallingterminal velocityNewton's Second Law of Motionshuttlecock

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    The River Breathes: Stream reach metabolism as an integrative and comparable measure of stream processes
    Stream reach metabolism integrates organism respiration & production to provide a valuable ecosystem measure that varies as a function of biotic & abiotic factors. As a powerful indicator of whole...

    Keywords: ecosystem respirationMetabolismriverRespirationproductionRiver Field Studies NetworkDissolved OxygenStream MetabolismEcosystem ProductionStreamField LessonGuided Student ReflectionStudent Reflection

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    Collaborative case writing and field testing with Molecular CaseNet brings together discipline specific expertise for innovative pedagogical tools in the classroom
    Molecular case studies (MCS) use an interesting story as a hook , followed by exploration of biochemistry of one or more molecules of interest.  They can be useful in teaching about macromolecule...
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    5-040-TunedMassDamper-Part-I-Modeling Scenario
    We offer an opportunity to build mathematical models to mitigate dangerous displacements in structures using structural improvements called Tuned Mass Dampers. We model the motion of the original...

    Keywords: structurespring-mass-dashpotspring massearthquakevibrationtuned mass tunerrestoring forcecontroldampe

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