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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    What Moves You?
    Using various bone segments to create joints that will explain planar movement and then develop a mechanical model of different joint types that will allow certain movement in a robotic unit.
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    Exploring Functions for Common Phage Proteins
    This resource is designed to help students better understand the functions of common structural and enzymatic phage proteins, and to relate these functions to phage structure using electron...
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    Plants in the Human-Altered Environment (PHAE): EREN-NEON Flexible Learning Project
    A project to compare effects of a continuum of landscape alteration intensities on plant diversity, biomass, and ecosystem services, and to explore human socioeconomic connections to plants in the...

    Keywords: erenNEONdiversitybiomass4DEE Frameworkecosystemsocioeconomic effects

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    Integration of Bioinformatics into Life Science Curricula: Community Development, Dissemination, and Assessment of a NIBLSE Learning Resource
    Big data and computational tools have transformed the way we address biological questions. To prepare undergraduates for tomorrow’s challenges, life science curricula should integrate the...

    Keywords: bioinformaticsNIBLSELife Science

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    Introduction to Genome Annotation
    This exercise is an adaptation of the Annotation Lesson by Rosenwald et al. It introduces the use of bioinformatics tools to extract information from genome databases. It is a basic lesson on...

    Keywords: microbiologyGenome annotationBioinformatics EducationBioinformatics and Genomics

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    Aquatic Nutrient Levels and Climate Change
    This learning module was designed to introduce students to the aquatic nutrients nitrogen and phosphorus, their roles in ecosystem function and nutrient pollution, and what impacts climate change...

    Keywords: climate changenitrogenwater resourcesfreshwater systemsEutrophicationwater qualitynutrient pollutionphosphorusdischargeTMDL

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    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

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    Adaptation of Investigating human impacts on stream ecology: locally and nationally
    TIEE Module- How does nutrient pollution impact stream ecosystems locally and nationally?
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    Amylase Copy Number and Diet
    An adapted module from HHMI Spreadsheet Tutorials using amylase data for students to gain data analysis and excel skills

    Keywords: Scientific ProcessStatistics and MathScientific Methodology

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    Spider Silk: Stress-Strain Curves and Young's Modulus
    This module introduces the stress-strain curve in the context of understanding materials' mechanical behavior. It is intended for an introductory biology audience.

    Keywords: structurestressbiomechanicsFunctionsstrainYoung's Modulusmechanical

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    Exploring the functionality of R
    Students work with example data to generate a length-weight plot and use lm() to obtain regression coefficients. Base plot functions are used to plot both the data and the regression line.
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    Finding Selection in All the Right Places
    Lab introducing students to evolutionary genetics using bioinformatics and biocuration, published as GSA Learning Resource

    Keywords: geneticsbioinformaticssequencingNIBLSE

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    Seed Dispersal in Tropical Forests: Learning How Plants Move Around
    This module focuses on the dispersal of seeds from trees in fragmented tropical forests. Students use data from published studies to understand patterns of seed dispersal and apply these ideas to...

    Keywords: ecologyResources @ HHMI - BioInteractivecommunityplantsdiversityScientific Process

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    IPMpack: an R package for Integral Projection Models
    IPMpack is an R package (R Development Core Team 2013) that allows users to build and analyse Integral Projection Models.

    Keywords: RR-Forgeanimalbiostatisticscomparative analysisecologylongitudinal datamodel comparisonmodel estimationprojectionssurvivaltime seriestrajectoryIPMintegral projection modelsResources @ QUBES - Software

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    Drug screening and cancer resistance: EGFR Activity
    This activity explores a specific gene (egfr) and its role in cancer. EGFR was introduced with the Gene Card Activities, researched throughout the semester, and then authentic image data of...

    Keywords: Resources @ HHMI - BioInteractivegenomicscancergenetic basis of diseasebiology of cells

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    Seed Dispersal in Tropical Forests - implementation at a small, Primarily Undergraduate Institution
    In this activity, students use data from published studies to understand patterns of seed dispersal and apply these ideas to the design of a conservation area.

    Keywords: ecologyResources @ HHMI - BioInteractivecommunityplantsdiversityScientific Process

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    Seed Dispersal in Tropical Forests
    In this activity, students use data from published studies to understand patterns of seed dispersal and apply these ideas to the design of a conservation area. This was applied through the lens of...

    Keywords: ecologyResources @ HHMI - BioInteractivecommunityplantsdiversityScientific Process

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    Understanding Protein Domains: A Modular Approach
    An understanding of protein structure, function, and interaction is central to biochemistry. One angle into this topic is to engage students in considering protein domains as modules that develop...

    Keywords: Protein Structure

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    Teaching Cell Structures through Games
    As the basic unit of life, cells are a foundational concept for all of biology. Before students can appreciate how eukaryotic cells function either in isolation or in higher order and multicellular...

    Keywords: Cell Structurecell organellesTransmembrane Transport

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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