You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    Module 1: Introduction to the Genome Browser: What is a Gene?
    This lesson introduces the University of California Santa Cruz genome browser to students, walking them through some of the key features so that it can be used for analysis of gene structure.

    Keywords: geneticsbioinformaticsGenome BrowserSimilarity searchesExonsIntronsEvidence TrackStart CodonStop Codon

    1235

    views

    2012

    downloads

    0

    comments

    0

    adaptations

    Sickle Cell Anemia using Nicholas’ Story
    The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...

    Keywords: Hemoglobinsickle cell diseaseMolecular Case Study

    1118

    views

    622

    downloads

    0

    comments

    0

    adaptations

    Mentoring Undergraduate Research Projects in Mathematical Biology
    Part of the 2015 SMB Minisymposium: Topics in Biomathematics Education

    Keywords: epidemiologymentoringcurriculumundergraduate researchGene regulatory networkpest management

    1417

    views

    203

    downloads

    0

    comments

    0

    adaptations

    GSEAtheory
    Brief introduction to how gene set enrichment analysis works.

    Keywords: videosbioinformaticsgenomicsyoutubegsea

    1315

    views

    246

    downloads

    0

    comments

    0

    adaptations

    A clicker-based case study that untangles student thinking about the processes in the central dogma
    The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students...

    Keywords: mutationtranscriptionphenotypecentral dogmatranslationDNA replication

    5298

    views

    902

    downloads

    0

    comments

    0

    adaptations

    Bioinformatics: the Power of Computers in Biology – a Practical Guide
    This Practical Guide in the Bringing Bioinformatics into the Classroom series introduces simple bioinformatics approaches for database searching and sequence analysis.

    Keywords: NIBLSEGOBLET

    1040

    views

    263

    downloads

    0

    comments

    0

    adaptations

    Module 2: Transcription Part I: From DNA Sequence to Transcription Unit
    This module illustrates how a primary transcript (pre-mRNA) is synthesized using a DNA molecule as the template. Students will learn about the importance of the 5' and 3' regions of the gene for...

    Keywords: data visualizationmolecular biologybioinformaticsGenome BrowsergenomicsTranscription InitiationTranscription Start SiteTranscription Termination Signal

    1656

    views

    3166

    downloads

    0

    comments

    0

    adaptations

    RNA-seq Analysis
    In this computer lab module, students learn how to process an RNA-seq data set to identify differentially expressed genes (DEGs). The samples for this data set were collected from yeast cells...

    Keywords: LabRNAsequencingUndergraduateNIBLSEincubatorsRNAseqInstructional SettingAudience LevelActivity LengthMore than 1 hourC4. Bioinformatics toolsC5. Data retrievalReviewed at NIBLSEdifferentially expressed genes

    1633

    views

    295

    downloads

    0

    comments

    0

    adaptations

    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

    327

    views

    31

    downloads

    0

    comments

    0

    adaptations

    Learning Quantitative Genetics: Investigation of Genetic Control for Cold Stress Response in Plants
    Course-embedded undergraduate research experiences (CUREs) for students have been shown to increase students’ understanding of the process of science, affirm their scientific identity, and...

    Keywords: data analysisrecombinationplantsquantitative geneticsabiotic stress responsegenetic control of complex traitsinheritance of complex traits

    2130

    views

    285

    downloads

    0

    comments

    0

    adaptations

    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    Students require a deep understanding of the central dogma before they can understand complex topics such as evolution and biochemical disorders. However, getting undergraduate biology students to...

    Keywords: Protein Structurecomputational modelingcentral dogmaplant leaf structurePhenotype/Genotype

    1937

    views

    511

    downloads

    0

    comments

    0

    adaptations

    Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners
    Manipulating gene expression is a commonly used tool to study the effect of a single gene or the hierarchy of gene networks in many different biological disciplines. When working with mice, the...

    Keywords: mathematical modelhomologous recombinationCre/loxgene targeting

    1502

    views

    212

    downloads

    0

    comments

    0

    adaptations

    Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience
    Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience...

    Keywords: EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

    3137

    views

    251

    downloads

    0

    comments

    0

    adaptations

    2008-Duran-Caginalp-Parameter optimization for differential equations in asset price forecasting
    The optimization procedure is used in conjunction with daily market prices (MPs) and net asset values to determine the parameters for which the AFDE yield the best fit for the previous n days.

    Keywords: financeinverse problemnumerical nonlinear optimizationasset flowfinancial market dynamicsmarket return prediction algorithm

    123

    views

    16

    downloads

    0

    comments

    0

    adaptations

    Figure of the Week: Environmental Data Analysis/Statistics Version
    Adaptation of Figure of the Day activity used on a weekly basis in an environmental data analysis/statistics course.

    Keywords: graphsmath attitudesResources @ BIOMAAPInterpreting Graphs

    1205

    views

    298

    downloads

    0

    comments

    0

    adaptations

    Fruit Fly Genetics in a Day: A Guided Exploration to Help Many Large Sections of Beginning Students Uncover the Secrets of Sex-linked Inheritance
    Moving beyond the basic concepts of autosomal Mendelian inheritance to sex-linkage can be difficult for introductory biology students. Although crosses with Drosophila fruit flies have long been a...

    Keywords: Mendelian Geneticsfruit fly biologysex-linked inheritance

    2911

    views

    863

    downloads

    1

    comments

    0

    adaptations

    Gene Expression in Stem Cells
    The module served as in introduction to the Gene Expression unit. It was implemented in two phases, a pre-class activity and an in-class activity to introduce chapter concepts and reinforce...

    Keywords: small group activitypre-class activityGeneral Biology

    3066

    views

    705

    downloads

    0

    comments

    0

    adaptations

    2017-Helen-Byrne-Further Mathematics Biology
    These studies will be in the context of ecological, biological and biochemical applications.

    Keywords: epidemicschemotaxisenzyme-substrateion channelsnerve pulsesgene proagationtumour

    150

    views

    37

    downloads

    0

    comments

    0

    adaptations

    Build Multiomic and Visualization Skills in Bioscience Lecture
    This resource promotes inclusive learning by using all free platforms to extend the central dogma to an applied experience. Genomics is focused on with literature reviews that are performed to...

    Keywords: geneticsBiochemistryBiology and Biochemistry EduationProtein StructureBioinformatics and GenomicsFunctional GenomicstranscriptomicsproteomicsRNAseqClinical genomicsprotein structure modelingInclusive teaching3D protein structure /function analysisinclusive classrooms3D protein structuresinclusivegene

    1096

    views

    224

    downloads

    0

    comments

    0

    adaptations

    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

    2510

    views

    754

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search