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    A 360˚ View of COVID-19
    In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new...

    Keywords: geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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    A clicker-based case study that untangles student thinking about the processes in the central dogma
    The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students...

    Keywords: mutationtranscriptionphenotypecentral dogmatranslationDNA replication

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    Overview of the Genomics Education Partnership
    Poster exhibited at the National Association of Biology Teachers (NABT) 2022 conference providing an overview of the Genomics Education Partnership including its benefits to faculty, students, and...

    Keywords: course-based undergraduate research experienceGenomics Education PartnershipNABT 2022

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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression.  This laboratory lesson allows students...

    Keywords: bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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    Using Synthetic Biology to Teach Data Science
    Poster and supplemental materials on using synthetic biology to introduce students to meaningful data mining, analysis, and application to engineering novel biological constructs.
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    Data Analysis and Cancer
    This is a flipped classroom approach, students will learn the basic content about cell-signaling, p53, and transcription factors before class. During class students will focus on data analysis...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologydata interpretationBiological Data Analysiscell cyclemacromoleculesGenetic diseaseCell signaling

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    1998-Elly_Claus-McGahan-Modeling Projects in a Differential Equations Course
    Here we discuss the value of student designed, in-depth, modeling projects in a differential equations course and how to prepare them for it.

    Keywords: projectswritingpopulationtankmixingcomputer-aided analysissprinting

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    1-039-StochasticPopModels-ModelingScenario
    We develop strategies for creating a population model using some simple probabilistic assumptions. These assumptions lead to a system of differential equations for the probability that a system is...

    Keywords: Probabilitypopulation dynamicsVarianceMeanstochasticdeterministic

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    1999-T_Chen-HL_He-GM_Church-S_Shafer-Modeling Gene Expression with Differential Equations
    The paper proposes and give great detail for a differential equation model for gene expression with two methods for constructing the model from a set of temporal data.

    Keywords: gene expressiongenekineticgene translationgene transcription

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    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters...

    Keywords: time seriesEvaluation SPLINEgeneleast squaresbifurcation

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    Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination
    Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom,...

    Keywords: nucleotidessequencingDNAgel electrophoresisChain Termination

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    From Dirt to Streptomyces DNA
    The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular...

    Keywords: MetabolismAntibiotic productionrRNA genesSecondary metabolitesStreptomyces

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    Differential Gene Expression during Xenopus laevis Development
    In Developmental Biology classes, students are challenged with understanding how differential gene expression guides embryonic development. It can be difficult for students to realize that genes...

    Keywords: gene expressionXenopusearly developmentembryofertilizationin situ hybridization

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    A Close-Up Look at PCR
    The Polymerase Chain Reaction (PCR) is a fundamental laboratory technique that allows for the amplification of many copies of a desired DNA target sequence. Despite its prevalence, undergraduate...

    Keywords: PCRDNA replication

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    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

    Keywords: datatranscriptionvirustranslationprotein functionmembrane transportPredictions

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    Hands-On, Hands-Off: The Community College Genomics (ComGen) Course-Based Undergraduate Research Experience
    Science is a process of discovery where failure is inherent and iteration is necessary, yet instructors often teach the scientific process as if it is a controlled, highly supervised, confirmatory...

    Keywords: geneticssequencingDNAbacterium

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    Digital Laboratory Framework via Canvas for LIFE courses at Colorado State University
    The Life Lab Revisions team has piloted a Canvas-based approach to building scientific competencies in labs.

    Keywords: online learningvirtual lab

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    Genome Solver: Building faculty skills in bioinformatics
    Genome Solver (GS) began in 2011 as an NSF-funded project for faculty training in basic web-based bioinformatics skills.

    Keywords: faculty developmentbioinformaticsgenome solver

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    Amylase Copy Number and Diet
    An adapted module from HHMI Spreadsheet Tutorials using amylase data for students to gain data analysis and excel skills

    Keywords: Scientific ProcessStatistics and MathScientific Methodology

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    Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab
    Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much...

    Keywords: Protein StructureproteaseEnzymechemical bondscatalysissolubility

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