Text Search:
Applied Filters
    Cystic Fibrosis Mechanism and Treatment
    This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop...
    1094

    views

    191

    downloads

    0

    comments

    0

    adaptations

    Amylase Copy Number and Diet
    An adapted module from HHMI Spreadsheet Tutorials using amylase data for students to gain data analysis and excel skills
    1353

    views

    1507

    downloads

    0

    comments

    0

    adaptations

    Cohort Life Tables
    This module introduces cohort life tables in the context of understanding demographic processes and how they affect populations. It is intended for an introductory biology audience.
    1028

    views

    375

    downloads

    0

    comments

    0

    adaptations

    Exploration of the Human Genome by Investigation of Personalized SNPs
    To increase students' interest in their own genomes, this computer-based laboratory lesson is designed to be coupled with the opportunity for the students to be genotyped by the consumer sequencing...
    1290

    views

    326

    downloads

    0

    comments

    0

    adaptations

    Regulation Across Scales: Data Points Icebreaker Jigsaw
    Students examine regulation at cellular, physiological, and ecological scales in a data-based jigsaw to explore how double-negative logic operates across biological systems. This was used as a...
    1008

    views

    387

    downloads

    0

    comments

    0

    adaptations

    T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection
    Article presenting evidence that the bitter taste receptor T2R38 regulates the mucosal innate defense of the human upper airway.
    588

    views

    105

    downloads

    0

    comments

    0

    adaptations

    Laboratory exercises on microbial growth, horizontal gene transfer, competition and evolution
    Simple laboratory exercises to reinforce student learning when performed in conjunction with NetLogo simulations.

    Keywords: microbiology

    1010

    views

    654

    downloads

    0

    comments

    0

    adaptations

    Calculating Lifetime Cancer Risk Resulting from DNA Replication
    An expanded case study adapted from an HHMI Data Point on Cell Division and Cancer Risk using Figure 1 from Tomasetti, C. and Vogelstein, B. (2015).
    1392

    views

    1014

    downloads

    0

    comments

    0

    adaptations

    Cancer Discovery Activities
    These two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video (http://www.hhmi.org/biointeractive/cancer-genetic-disease-video-highlights)...
    1826

    views

    320

    downloads

    0

    comments

    2

    adaptations

    A Hands-on Introduction to Hidden Markov Models
    In this Lesson, we describe a classroom activity that demonstrates how a Hidden Markov Model (HMM) is applied to predict a eukaryotic gene, focusing on predicting one exon-intron boundary. This HMM...
    3070

    views

    647

    downloads

    0

    comments

    0

    adaptations

    Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples
    Historically, undergraduate genetics courses have disproportionately focused on the impact of genes on phenotypes, rather than multifactorial concepts which consider how a combination of genes, the...
    2522

    views

    373

    downloads

    0

    comments

    0

    adaptations

    Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms
    Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell...
    1917

    views

    365

    downloads

    0

    comments

    0

    adaptations

    Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience
    Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and...
    5920

    views

    1010

    downloads

    0

    comments

    0

    adaptations

    Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination
    Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make...
    2443

    views

    550

    downloads

    0

    comments

    0

    adaptations

    Computational Biology using R
    This is an introductory level course on computational biology.
    1587

    views

    446

    downloads

    0

    comments

    0

    adaptations

    Student-Generated Analogies for Learning about Information Flow
    Using analogies is a standard practice for both teaching and communicating ideas in science. Here we upend the traditional lesson, where the instructor provides a fully constructed analogy and...
    517

    views

    67

    downloads

    0

    comments

    0

    adaptations

    GEA Introductory lesson on BLAST
    The "Introduction to BLAST using Human Leptin" exercise aims to introduce students to the use of the Basic Local Alignment Search Tool (BLAST) to identify related sequences and compare similarity...
    1434

    views

    1193

    downloads

    0

    comments

    0

    adaptations

    HITS: A network to create inquiry-based case studies that make high-throughput approaches and discovery accessible
    HITS brings together interdisciplinary groups of HT researchers and instructors to produce authentic HT case studies that can be implemented in a variety of courses, allowing students to analyze...
    3070

    views

    633

    downloads

    0

    comments

    0

    adaptations

    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.
    1157

    views

    484

    downloads

    0

    comments

    0

    adaptations

    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.
    1600

    views

    506

    downloads

    0

    comments

    4

    adaptations