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    Lizard cold tolerance and extreme weather events: a scientist spotlight featuring Dr. Shane Campbell-Staton
    Students interpret experimental and observational data about patterns in cold tolerance in the green anole. They reflect on the experience and identity of the lead researcher based on a video...

    Keywords: climate changeNatural Selectionenvironmental variationphenotypic plasticityacclimationenvironmental conditions

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    Data Analysis and Cancer
    This is a flipped classroom approach, students will learn the basic content about cell-signaling, p53, and transcription factors before class. During class students will focus on data analysis...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologydata interpretationBiological Data Analysiscell cyclemacromoleculesGenetic diseaseCell signaling

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    2016-Lofgren-EtAl-Equations of the End Teaching Mathematical Modeling Using the Zombie Apocalypse
    In this article, we explore several uses of zombie epidemics to make mathematical modeling and infectious disease epidemiology more accessible to public health professionals, students, and the...

    Keywords: simulationinfectious diseasediseaseepidemicZombieWhite Zed

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    Investigating Sexually Transmitted Disease (STD) Ecologies Using Geographic Information Systems (GIS) (Abstract) | TIEE
    Identifying, mapping and understanding the magnitude and the spatial prevalence of the Sexually Transmitted Diseases (STDs) such as chlamydia and gonorrhea diseases. Analyzing the spatial trends of...

    Keywords: Resources @ ESA - TIEEDisease ecologyfmnDIGhuman ecology and behaviorbacterial infectionsspatial and temporal spread of diseaseGeographic Information System (GIS)

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    A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics
    Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need...

    Keywords: epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

    Keywords: transcriptioncentral dogmatranslationsequence analysisDNA replicationgenetic variants

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    Quantifying Bacterial Growth in the Guts and Hemolymph of Fruit Flies: Mathematical Modeling and Data Interpolation/Extrapolation
    In this activity, students will analyze raw data obtained from an experiment that explores the effect of overexpressing the Ssk protein in order to strengthen the intestinal barrier and prevent...

    Keywords: graphingexponential growthlinear modelsqbccinterpolationConcepts in Statistics and Precalculus Understanding exponential rates and linear slopesExtrapolation

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    A CRISPR/Cas Guide RNA Design In Silico Activity
    CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become...

    Keywords: bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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    Cross-Course Public Health Project on Infectious Disease
    The need for collaborative, public health education has never been more important. Students increasingly require necessary skills in effectively communicating critical information to the general...

    Keywords: infectionpublic healthVaccinespathogenesisantibiotics

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    Social Distancing Simulation in NetLogo
    A NetLogo simulation that shows the effects of social distancing on the spread of infectious disease.
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    Building student literacy and metacognition through reading science in the news
    Ensuring students' science literacy is essential for preparation for study in science disciplines and is of critical importance given contemporary challenges in determining the legitimacy and...

    Keywords: metacognitionStem cellsscience literacycloninggenetically modified organismshuman genetic diseasescience news

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    Connecting Viral Pandemics to Ecological Population Growth Models
    In this activity students use the HHMI Population Growth Models interactive to explore R0 for diseases and discuss the importance of connecting population ecology to current events like the...
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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

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    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how...

    Keywords: pathwayscancerMolecular AlterationsRetrospective dataTumorigenesis

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    Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms
    Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell...

    Keywords: mutationcancertranscriptioncell cycletranslationOncogenesTumor-suppressorp53Transcription factor

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    6-045-CholeraTranmission-ModelingScenario
    During the project described here, the students will learn how to solve and address a practical problem such as cholera transmission using various mathematical tools.

    Keywords: infectious diseasecholeraendemicdisease-freetransmission ratewaterborne pathogen

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    Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers
    Most introductory genetics courses cover genetic linkage, a core concept in the CourseSource genetics learning outcome framework. Although it is a classical genetics topic, genetic linkage remains...

    Keywords: meiosisphenotypegel electrophoresismicrosatellitesBanding PatternGenetic linkageInheritanceMolecular MarkersPhysical Linkage

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    2012-Tweedle-Smith-Mathematical model of Bieber Fever-The most infectious disease of our time
    We develop a mathematical model to describe the spread of Bieber Fever, whereby individuals can be susceptible, Bieber-infected or bored of Bieber.

    Keywords: infectious diseasediseaseinfectionmediaJustin BieberBieber feversymptomsboredreproductive ratio

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    My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships
    To facilitate understanding of the fundamental genetic concept of the genotype-phenotype relationship in our introductory biology students, we designed an engaging multi-week series of related...

    Keywords: gel electrophoresissequence analysiscanine geneticsdeoxyribonucleic acid (DNA)dog coat morphologygenotype and phenotypemutationsPolymerase chain reaction (PCR)single nucleotide polymorphism (SNP)

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    Workshop Report: Summer 2020 Virtual CRISPR in the Classroom
    As innovations and developments in genome editing technologies using CRISPR-Cas systems progress, the need to disseminate relevant knowledge and build skills among the next generation of young...

    Keywords: geneticscrisprGenome Analysisgene editingbacterial immunity

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