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    Assessment: When tests disagree, how do I know if I have COVID-19?
    In this activity, students learned about the immune response to infection by exploring different types of tests—PCR, antigen, and antibody tests—to detect SARS-CoV-2 viral genetic material,...

    Keywords: ImmunologyPCRCOVID19SARS-CoV-2structure and functionImmunoReachantigen-antibody interactionInformation FlowAntigen testAntibody test

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    Protein Import Into the ER: Understanding Experimental Methods for Old and New Cellular Discoveries
    Process Oriented Guided Inquiry Learning (POGIL) is an effective approach for group work in STEM courses. POGIL-style lessons foster active learning because they require students to communicate and...

    Keywords: Necessary and sufficientsignal sequenceProtein SynthesistrafficER importTranslocation

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    Osmosis Through the Lens of Sexual Health
    Osmosis contributes to a range of biological phenomena, from functioning of nephrons in animals to stomatal opening and closing in plants; yet, scientifically simple ideas about osmosis are common....

    Keywords: OsmosisDiffusionsexual healthsocial and cultural embeddedness of scienceinclusive dialogue

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    X-ploring Fragile X: The Science Behind the Syndrome
    Fragile X Syndrome is an X-linked genetic disorder resulting from the impairment of transcription of the FMR1 gene, producing less to no FMRP protein. FMRP is a translational inhibitor that plays a...

    Keywords: epigeneticsgene regulationtranscriptioncentral dogmatranslationFragile X syndromeSphingosine Metabolism

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    Trail Camera Field Survey Module
    This QUBES module introduces high school students to the exciting world of field surveys using trail cameras. Designed for environmental science classes, the module offers a hands-on approach to...

    Keywords: graphsspecies richnessCommunity EcologymammalsMicrosoft Exceldichotomous keycamera trapsShannon diversity indexTrail CamerasPivotTables

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    Adapting a Traditional Laboratory Exercise to Become Inquiry Based: An Example With an Introductory Biology Lab in Diffusion
    Authentic research experiences are effective in fostering self-efficacy and increasing retention in STEM, particularly among minoritized student populations. Many instructors have sought to bring...

    Keywords: protocolquestionDiffusionVariableshypothesisscience processcontrolscientific efficacy

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    Space Mission Ecology: Making Connections Among Science Disciplines Through the Lens of a Unique Plant
    With this case study, we aim to increase awareness of essential services plants provide to society, as well as the importance of fundamental aspects of ecology for other disciplines and the...

    Keywords: ecologycollaborationplant biologyScience CommunicationBioregenerative Life SupportInterdisciplinary Connections

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    The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics
    Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both...

    Keywords: bioethicsCRISPR/Cas9Genetic modificationGene drives

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    Phylogeography Simulator
    This Excel workbook simulates the phylogeography of an asexually reproducing species.

    Keywords: Phylogeographymutation ratesAsexual reproductionspecies dispersal

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    Genetic Code
    This Excel workbook allows the user to recreate the steps in breaking the genetic code. The user enters the sequence of repetitive synthetic mRNA strands, which are translated in vitro to produce...

    Keywords: mRNAgenetic code

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    Deme 2.0
    This workbook simulates the population genetics of a single gene with two alleles. It can simultaneously model up to three local populations, which may differ in their selection coefficients.

    Keywords: population geneticsGenetic DriftNatural Selection

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    DeFinetti 1.0
    This Excel workbook simulates evolution of a single gene with three alleles. The user assigns fitness values to each of the six possible genotypes, then enters starting allele frequencies for each...

    Keywords: population geneticsallelesevolutionary fitness

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    COVID-19 Model
    This Excel worksheet implements an SEAIHRD model for Covid-19 (Susceptible, Exposed, Asymptomatic infective, symptomatic Infective, Hospitalized infective, Recovered, Deceased).

    Keywords: infectious diseaseCOVID19

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    Using genomic data and machine learning to predict antibiotic resistance: a tutorial paper
    Antibiotic resistance is a global public health concern. Bacteria have evolved resistance to most antibiotics, which means that for any given bacterial infection, the bacteria may be resistant to...

    Keywords: Tutorialmachine learningantibiotic-resistanceArtificial Intelligence

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    Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar
    This unit, Defining Life, engages students in thinking like scientists, applying creativity to science, and learning biology core concepts as they explore the defining characteristics of life. This...

    Keywords: Evolutionbiologycellprocess of science

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    Cancer Genetics and an Interview with a Deaf Biomedical Researcher
    In this lesson, learners will learn about cancer genetics and understand and interpret graphs showing quantitative trait locus (QTL) data, survivor curve data, and other genetics data. Then,...

    Keywords: graph interpretationfmnDeaf EducationBioGraphIrepresentation in STEMBioGraphI graph InterpretationDeaf representation in STEM

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    A Structured Inquiry-Based Module for the Undergraduate Cell Biology Laboratory That Teaches Fundamental Concepts of Cell Differentiation
    Pedagogical research in science education has shown that students effectively learn science by doing science. As a result, there is increased interest in bringing research-like experiences into the...

    Keywords: fluorescence microscopygene expressionpolymerase chain reactionCell Structurecell culturewestern blottingdifferentiationreverse transcription

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    Exploring Microbial Diversity: An Interactive In-Class Assignment for Biology and Microbiology Courses
    This interactive assignment engages students in a hands-on exploration of microbial diversity and the importance of microbes in ecosystems. Designed for General Biology II and Introduction to...

    Keywords: Microbiology EducationMicrobial DiversitymicrobiologyEcological Society of Americaecology educationresearch-based classroom instruction4DEE Framework

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    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...

    Keywords: case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

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    Navigating Bacterial Changes in Aging Organisms: Graphs, Patterns, and Models
    Aging is an incredibly important area of research, and recent biological advances implicate the intestines in aging pathologies. Given that the gut harbors an immense amount of an organism’s...

    Keywords: statisticsgraphingmathematics for life sciencesmathexponential growthPrecalculus

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