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    Regulation of Sex Determination
    This activity accompanies the HHMI BioInteractive module Sex Verification of Athletes (​https://www.hhmi.org/biointeractive/testing-athletes​). It provides students with exercises to explore the...
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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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    Meiosis: A Play in Three Acts, Starring DNA Sequence
    Meiosis is well known for being a sticky topic that appears repeatedly in biology curricula. We observe that a typical undergraduate biology major cannot correctly identify haploid and diploid...

    Keywords: recombinationmeiosisDNA sequenceCrossingoverchromosome structureHolliday junctionhomology

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    The Case of the Missing Strawberries: RFLP analysis
    While solving the fictional mystery of the missing strawberries, students are engaged in a guided-inquiry lesson featuring small-group and class discussions, hands-on activities, and laboratory...

    Keywords: process of scienceDNAforensicsgel electrophoresisMolecular genotypingRestriction endonucleaseRestriction enzymeRestriction fragment length polymorphismRFLP

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    Examining the Physiology Behind the Symptoms of Lactose Intolerance
    This is a set of extension questions for the HHMI short film The Making of the Fittest: Got Lactase? The Co-evolution of Genes Video Activity.
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    Half Life of mRNA
    This module introduces exponential growth and decay in the context of understanding the stability of mRNA. It is intended for an introductory biology audience.

    Keywords: exponential equationsGenetic Informationlogarithmic equationshalf-lifemRNA

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    Population Bottlenecks: Heterozygosity vs. Allelic Diversity
    This module introduces heterozygosity and allelic diversity in the context of understanding population bottlenecks. It is intended for an introductory biology audience.

    Keywords: Ratiosexponential equationsAlgebraGenetics and Evolution

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    Computational Biology using R
    This is an introductory level course on computational biology.

    Keywords: simulationmoduleRcourseprojectsolutions

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    Linked Genes and Recombination: Advanced Punnett Squares
    An online module in which students learn about more difficult genetics problems, including linked genes and crossing over. Quantitatively students learn about marginal probabilities and chi-square...

    Keywords: geneticsProbabilityResources @ MathBenchonlinepunnett squareslinked genes

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    Math Bench Probability and Statistics: Basic Rules of Probability
    MathBench resource covering the "Law of Or" and the "Law of And" and how to use them in an online setting

    Keywords: ProbabilityResources @ MathBenchonlinerule of orrule of and

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    Bioimage Informatics Activity
    Students use basic bioimage informatics techniques to acquire quantitative data from images of cultured cells and test a hypothesis about the effect of a genetic mutation on cellular phenotypes

    Keywords: geneticsResources @ HHMI - BioInteractivegenomicscancergenetic basis of diseasebiology of cells

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    A BioGraphy of Life: How Graph Theory Makes Mathematics Recognizable, Relevant, and Research-Rich in Biology Education
    Presentation given at the 2106 SIAM Conference on Applied Mathematics Education on graph theory.

    Keywords: graph theory

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    Sickle Cell Disease Case Study
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    Processes that Regulate Patterns of Species and Genetic Diversity
    This activity was developed for an undergraduate upper level ecology course for Environmental or Biological Science majors. Classes of ~20 students work best for the activity.
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    A 360˚ View of COVID-19
    In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new...

    Keywords: geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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    Ground Spider Survey QUBES Resource Draft (1)
    This QUBES Module aims to introduce students to standardized ecological field methods, measures of diversity, ArcGIS Online, and Excel. This is achieved through nocturnal survey of ground spiders.

    Keywords: Community EcologyspidersMicrosoft ExcelShannon diversity index

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    1969-Carl_Metzler-A mathematical model for the pharmacokinetics of LSD effect
    Contains data on performance scores vs. plasma levels of LSD in human tissues.

    Keywords: LSDtestingpharmacokineticsperformanceplasma level

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    Grassy Narrows and Muskrat Falls Dam: The Central Limit Theorem and a t-test
    Students are introduced to concepts of sampling distributions and hypothesis testing using a simulation applet, elementary hypothesis tests, t-tests, and p-values as they compare a given fish...

    Keywords: statisticsmathematicsbiostatisticsecologybiologygraphingp-valuest-testshypothesis testingin-class activityZoologymercury biogeochemistrybiostatistics - generalfish populationqbccBiogeochemical cyclesInterpret graphsSolving Equations and InequalitiesConcepts in StatisticsElementary Hypothesis TestingMethylmercurydamsBioaccumulationtraditional dietsmercurymercury poisoningnative peopleindigenous populationCanadahydroelectricexplaining statisticsusing statisticsMake probability calculations

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    Using Grassy Narrows in a Live Classroom with Clicker Questions and Interactive Histogram: Sampling Distributions, Probability, and Hypothesis Testing
    Students are introduced to concepts of sampling distributions, p-values, and hypothesis testing. Using both simulated and real data for methylmercury level in fish populations, students will...

    Keywords: statisticsmathematicsbiostatisticsecologybiologygraphingp-valuest-testshypothesis testingin-class activityZoologymercury biogeochemistrybiostatistics - generalfish populationqbccBiogeochemical cyclesInterpret graphsConcepts in StatisticsElementary Hypothesis TestingMethylmercurydamsBioaccumulationtraditional dietsmercurymercury poisoningnative peopleindigenous populationCanadahydroelectricexplaining statisticsusing statisticsMake probability calculations

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    Investigating human impacts on stream ecology: locally and nationally
    TIEE Module- How does nutrient pollution impact stream ecosystems locally and nationally? This is an adaptation of the module that includes statistical testing and links sections to a lab report...
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