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    Amino Acid Frequency
    This module introduces expected frequencies in the context of understanding amino acid composition. It is intended for an introductory biology audience.

    Keywords: Probabilitylinear regressionamino acidsOpenStaxGenetic InformationAminoAmino Acid Freuency

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    Cancer Discovery Activities
    These two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video (http://www.hhmi.org/biointeractive/cancer-genetic-disease-video-highlights)...

    Keywords: geneticsResources @ HHMI - BioInteractiveorganismal biologyneurosciencegenomicscancergenetic basis of diseasebiology of cellsHigh School

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    2012-Nokkaew-EtAl-Estimation of Algae Growth Model Parameters by a Double Layer Genetic Algorithm
    This paper presents a double layer genetic algorithm (DLGA) to improve performance of the information-constrained parameter estimations.

    Keywords: optimizationalgae growthgenetic algorithmssimulated dataconvergence of parameters

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    Phenotypic plasticity and predation
    Students predict changes to tadpole morphology and coloration after considering characteristics of the predator species and the prey themselves then test their own hypotheses (typically with...

    Keywords: RExcelimage analysisgraphingt-testsfrequency histogramsdata visualizationANOVAhypothesis formulationpredator-prey interactionsphenotypic plasticity

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    Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model Organism
    Model organisms are commonly used to study and experimentally explore biological processes in ways that are technically or ethically not possible in humans. For this reason, model organisms are an...

    Keywords: exerciseenzyme kineticsmetabolite concentrationmodel speciesphysical activity

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    A Rapid Genetic Screen Using Wisconsin Fast Plants®: A Hands-On Approach to Inheritance of de novo Mutations
    Some concepts in genetics, such as genetic screens, are complex for students to visualize in a classroom and can be cumbersome to undertake in the laboratory. Typically, very large populations are...

    Keywords: mutationInheritancegermlinesomaplant lifecycle

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    Student-Generated Analogies for Learning about Information Flow
    Using analogies is a standard practice for both teaching and communicating ideas in science. Here we upend the traditional lesson, where the instructor provides a fully constructed analogy and...

    Keywords: critical thinkingcentral dogmaanalogical reasoning

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    Cutthroat trout in Colorado: A case study connecting evolution and conservation
    Evaluation of evidence is a key process skill for the core competencies of applying the process of science and using quantitative reasoning. This case study enables upper-division biology students...

    Keywords: population geneticsphylogeneticsSpeciationdivergencegene flow

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    Colon Cancer: A Case of Genetic Bad Luck
    Case study developed for an introductory genetics class published in the National Center for Case Study Teaching in Science

    Keywords: bioinformaticsNCBINIBLSEBLASTPublished in National Center for Case Study Teaching in Sciencecolon cancerpedigreegenetic testingAPC

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    Processes that Regulate Patterns of Species and Genetic Diversity - Intro Environmental Science
    This activity was adapted for use in an intro non-majors Environmental Science course, with an emphasis on collaborative data collection.

    Keywords: data analysisGenetic Driftquantitative skillsspecies diversityIsland biogeographygamificationgenetic diversityecological driftcolonizationcollaborative data collection

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    Phylogenetic analysis using collections material: interpreting trait evolution by comparison of morphological and molecular genetic hypotheses
    Exercise spans two weeks, includes homework, and involves some groups of animals as well as plants. Emphasizes re-interpretation of morphological trait evolution following molecular genetic...

    Keywords: Evolutionmorphologyphylogenylaboratoryplantsbiological collectionsmolecular analysis

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    Defenses against predation: Interpreting graphs of predator behavior
    In this lesson, students discuss anti-predator defense mechanisms and the types of cues defenses provide to predators. Students then interpret graphs of behavior of arthropod predators when...

    Keywords: graph interpretationfmndata literacyinterspecific interactionsconsumptionBioGraphIrepresentation in STEMarthropodsaposematismphenotypic variationtortoise beetlecarton-nest antspraying mantisorb-weaving spider

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    2017-Helen-Byrne-Further Mathematics Biology
    These studies will be in the context of ecological, biological and biochemical applications.

    Keywords: epidemicschemotaxisenzyme-substrateion channelsnerve pulsesgene proagationtumour

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    Developing quantitative skills for ecological data: the effects of climate warming on phenological variation and species interactions
    Students combine long-term observational data sets and experimental warming in an alpine meadow in Gothic, CO to test, evaluate, and interpret ecological data focusing on phenological variation and...

    Keywords: species interactionsclimate changequantitative skillsphenologyenvironmental variationphenological mis-match

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    Math and Stats in the Biology Classroom with HHMI BioInteractive
    Conquer basic math and statistics used in biology while exploring classroom-ready resources. Concepts include central tendency and variation, spreadsheet skills, graphing, and data analysis with...

    Keywords: HHMI BioInteractive

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    Fragile States: A Case Study Exploring Genetics, Molecular Biology, and Biochemistry Through the Lens of Fragile X Syndrome
    This case aims to strengthen students’ understanding of molecular biology concepts through study of Fragile X Syndrome (FXS). Students begin by learning the cause and phenotypes of FXS and...

    Keywords: gene regulationtranscriptiontranslationFragile X syndrometriplet repeat expansionsex linkagemetabolic pathway

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    Predicting and classifying effects of insertion and deletion mutations on protein coding regions
    Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...

    Keywords: mutationcentral dogmatranslationframeshift

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    Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination
    Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make...

    Keywords: geneticsdevelopmentmutationgerminationplantmodel organismGenotype/PhenotypeHormoneSeed

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    DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.
    Advances in high-throughput techniques have resulted in a rising demand for scientists with basic bioinformatics skills as well as workshops and curricula that teach students bioinformatics...

    Keywords: geneticsbioinformaticsDNAgenotypephenotypegenegene annotation

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    Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience
    Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience...

    Keywords: EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

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