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    Rivers as Social-Ecological-Technological Systems: Integrative Issue Formulation and Problem Solving
    Flowing surface waters continue to capture the human imagination and are increasingly harnessed by many interdependent human activities. Existing theories for studying rivers as cohesive ecological...

    Keywords: Interdisciplinary STEMProblem based learningcomplex systemsexperiential learningRiver Field Studies Network

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    COVID-19: Molecular Basis of Infection-ADAPTATION
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

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    Sleep and Learning Lab
    Students use sleep and exam data from Introductory Biology students to investigate the question: Does a circadian rhythm, the sleep-wake cycle, influence an important mammalian adaptation, the...

    Keywords: animal behaviorlab activitycircadian biologysmall group workthink-pair-shares

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    Maria vs Malaria - AR Adaptation
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria. Students will be able to view selected molecular views from the...

    Keywords: bioinformaticsAugmented RealityLarge class sizemolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    2014-Hrydziuszko-EtAl-Mathematical Two-compartment Model of Human Cholesterol Transport
    We develop a two-compartment mathematical model to investigate cholesterol transport in the circulatory system and its de novo synthesis in the liver.

    Keywords: metabolic syndromecompartmentcholesteroltwo-compartment modelcholesterol transport

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    2010-Shianga-EtAl-Computational model of the human glucose-insulin regulatory system
    A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The

    Keywords: glucose tolerance testsum of squared residualsmultiple shooting methodcost function

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    Integrating the modeling of biogeochemical cycles and energy flow
    This in-class activity challenges students to create and then integrate models of how carbon, nitrogen, water and energy all move within an ecosystem. Using 15 provided standard pools, they work...

    Keywords: modelingecologyintegration4DEE FrameworkBiogeochemical cycles

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    COVID-19: Molecular Basis Infection Revisited One Year into the Pandemic
    This adaptation was written in Spring 2021 exactly one year after the original case and includes explorations of the emerging mutations within the spike protein

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Studyvariantsantibody

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    Examining human impacts on tusk evolution in elephants using authentic research data
    In this activity students explore and analyze real, authentic research data paired with HHMI’s “Selection for Tuskless Elephants” video in a hands-on investigation of human impacts on elephant...
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    Plotting Cranial and Spinal Nerve Pathways in a Human Anatomy Lab
    Hands-on experiences with cadavers, animal dissections, or plastic models are effective at improving student learning and attitudes in human anatomy courses. The hands-on experience allows students...

    Keywords: human anatomyNervous systemBrainCranial nerveNerveSpinal cordSpinal nerve

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    Applying ESA’s 4DEE framework to guide the development of ecological literacy for non-majors
    The Four-Dimensional Ecological Education (4DEE) framework, endorsed by the ESA Governing Board in November 2018, is the culmination of 30 years of work by the ecology community to clearly define...

    Keywords: ecology4DEE Frameworkecological literacy

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    Ethics in Synthetic Biology
    This collection of five activities provide students with an introduction to thinking about ethical concerns in human genome synthesis, gene editing, metabolic engineering, and synthetic genomes.

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Investigating human impacts on stream ecology: locally and nationally
    TIEE Module- How does nutrient pollution impact stream ecosystems locally and nationally? This is an adaptation of the module that includes statistical testing and links sections to a lab report...
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    Investigating Human Impacts on Hawaiian Fishpond Ecology
    Examining water quality (including fertilizer residue, nutrients, soil erosion, and invasive plants) on a Hawaiian fishpond ecosystem.

    Keywords: sustainabilityecologywater quality and resource allocationocean sustainabilityinvasive plantsfisheries science

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    Investigating human impacts on local Hawaiian stream ecology
    Students learn about stream ecology on the island of Hawaii using data available through USGS and University of Hawaii websites and develop an understanding for potential stream changes due to...

    Keywords: climateStream ecologyHawaii CountyTopographyMap ReadingRainfall

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    Tools: New tools for new science
    A collection of computational, modeling and data analysis tools developed at Microsoft Research Labs.

    Keywords: modelingdata analysisdatacomputational toolsdata visualization

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    AMS Mathematical Moments
    Discover the world of mathematics with Mathematical Moments, 8.5'' x 11'' pdfs, available in many different scientific topics.  

    Keywords: case studymathadvertisingsocietyResources @ AMSResources @ QUBES - Teaching & Referencesciencepictiresclassrooms

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    Steve Palumbi and Megan Morikawa Study Coral Reef Damage in American Samoa
    Field research on coral bleaching suggests possibilities for saving threatened reefs.

    Keywords: ecologyResources @ HHMI - BioInteractiveVideoBiodiversityclimateAnimalsScientific ProcessScientific Methodologyearth and environmenthuman impactsscientists at workdiversity of organismsHigh School

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    Interactions between Water, Earth’s Surface, and Human Activity
    This two-week (~10-hour) module focuses on water and its importance to humans, both as a limited resource and in shaping Earth's surface.

    Keywords: earth scienceenvironmental sciencegeosciencewater resourcesResources @ InTeGrate

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    Pharmacokinetics
    This Excel module explores how drugs are processed and absorbed in the human body.

    Keywords: drug metabolismpharmacokinetics

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