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    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    Incorporating authentic research experiences into undergraduate labs, while shown to be particularly effective at engaging and retaining students in STEM majors, can be difficult to accomplish...

    Keywords: gene regulationmicroRNAsgene expression

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    A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation
    Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is...

    Keywords: mutationProtein Structureethicscentral dogmahuman disease

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    The Inside and Outside the Body
    The Inside and Outside the Body activity helps students develop a conceptual understanding of anatomical barriers such as skin and mucus membranes that separate internal cells and fluids from the...

    Keywords: structureAnatomybarriers

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    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how...

    Keywords: pathwayscancerMolecular AlterationsRetrospective dataTumorigenesis

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    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

    Keywords: datatranscriptionvirustranslationprotein functionmembrane transportPredictions

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    A Student-Led Hearing on the Use of HeLa Cells in Research
    In this role-playing case study, students will learn about the HeLa cell line and its origins while examining multiple perspectives surrounding the cell line and its uses. The goal of this case...

    Keywords: bioethicsscience policycell culturedebateHeLa cellsinformed consentrole playsocial justice issues

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    Modeling the Research Process: Authentic human physiology research in a large non-majors course
    Laboratory experiences in large-enrollment introductory science courses often utilize “cookie-cutter style” laboratory experiences due to the relative simplicity of setting up the lab...

    Keywords: data analysishypothesis testingexperimental designphysiology

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    An Open Source, Collaborative Electronic Notebook for Undergraduate Laboratory Classes
    To overcome many of the limitations of the paper laboratory notebook (PLN), we developed an electronic laboratory notebook (e-LN) for the Dynamic Genome course at the University of California. The...

    Keywords: data collectionData annotationNotebook Skills

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    The Three Sisters of Agriculture: An Active Learning Activity on Symbiotic Nitrogen Fixation
    This active learning exercise introduces students to the plant microbiome and the contributions that bacteria make to plant growth and food production. The Three Sisters are an ancient indigenous...

    Keywords: SymbiosisPlant microbiomeNitrogen fixationNutritional content of foodElectron flowSociety impact of microorganisms

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    Problem-Based Learning for Physiology: Synthesizing the Cardiovascular System, Respiration, Macronutrient Metabolism, and Renal Function
    Problem Based Learning (PBL) is a valuable tool for helping students overcome reliance on memorization by scaffolding opportunities for them to practice the competency of...

    Keywords: MetabolismObesityblood pressurecardiac functioncardiovascularmetabolic syndromerenalRespirationrespiratory system

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    A virtual laboratory on cell division using a publicly-available image database
    Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams....

    Keywords: image analysismicroscopymitosisCellular Processes

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    Facilitating Scientific Literacy Through Writing: A Write-to-Learn Assignment for Large Introductory Undergraduate Biology Courses
    Write-to-learn (WTL) assignments have been used in a variety of disciplines to encourage conceptual learning and critical thinking in undergraduate education. These assignments focus on...

    Keywords: geneticsEvolutionecologyCellsPlants form and functionAnimals form and function

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    Population Ecology of the Northern Spotted Owl
    The mathematical modeling of populations utilizing field-collected demographic data is an important component of lab curricula in a variety of undergraduate biology lab courses. During the global...

    Keywords: demographyCommunity Ecologypopulation ecologyconservation biologylife tables

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    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

    Keywords: transcriptioncentral dogmatranslationsequence analysisDNA replicationgenetic variants

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    Squirreling from Afar: Adapting Squirrel-Net Modules for Remote Teaching and Learning
    The shift from face-to-face instruction to remote teaching and learning has proven to be a challenging endeavor for many reasons, including lack of time, resources, and inspiration. Lab courses,...

    Keywords: online learningbehavioral ecologyCUREsRemote teachingfield ecologySquirrelSquirrel-Net

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    Predicting and classifying effects of insertion and deletion mutations on protein coding regions
    Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...

    Keywords: mutationcentral dogmatranslationframeshift

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    Causes and consequences of resisting herbivory: How long-lived plants avoid damage from diverse short-lived insect herbivores
    This module guides students through decades-long studies of tropical plant-insect interactions to elucidate the ecology and evolution of plant defenses while encouraging students to consider the...
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    An Introduction to Revealing Hidden Figures through Data Sleuthing
    In this introduction to hidden figures in natural history collections (NHCs), students will read an article that gives a unique historical perspective of museums and will then participate in a...

    Keywords: identitysocial justicenatural history collectionsAttributionBCEENETdigitizationRepresentationcourse-based undergraduate research experiences (CUREs)hidden figuresdata democratizationrestorative practice

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    Snapshot Serengeti Online Lab
    Snapshot Serengeti is a fully online inquiry-based lab that uses real camera-trap data from Serengeti National Park in Tanzania to explore themes of tropical ecology and animal behavior.

    Keywords: ecologyspecies interactionscitizen scienceCommunity Ecologyanimal behaviormigration ecologyScience Communicationspecies distributionspredator-prey interactionsTropical ecologycamera trapsSerengetisavannah biome

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    When tests disagree, how do I know if I have COVID-19?
    Students will learn about infectious disease and the immune response to infection by investigating different types of tests (PCR, antigen, and antibody tests) to detect the SARS-CoV-2 viral genetic...

    Keywords: geneticsVision and Changeintroductory biologyinfectious diseasemolecular biologycore competenciesRT-PCRviruscore conceptsnon-majors biologySARS-CoV-2antibodyAntigenImmunoReachmolecular DiagnosticsCOVID-19 transmission

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