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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

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    Why are Cells Small? Surface Area to Volume Ratio
    This module explores surface area to volume ratios in a cube and sphere in relation to cell size.

    Keywords: introductory biologygraphingRatiosOpenStaxqbccmanipulate equationsCellular and Molecular BiologyUse elementary functionsCreate graphsInterpret graphsRates and ProportionsSolving Equations and Inequalitiesinterpret tables

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    Exploring Microbial Diversity: An Interactive In-Class Assignment for Biology and Microbiology Courses
    This interactive assignment engages students in a hands-on exploration of microbial diversity and the importance of microbes in ecosystems. Designed for General Biology II and Introduction to...

    Keywords: Microbiology EducationMicrobial DiversitymicrobiologyEcological Society of Americaecology educationresearch-based classroom instruction4DEE Framework

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    3-071-WirelessTelegraphy-ModelingScenario
    This project has three parts, (1) done at home, (2) and (3) in class. In (1) we recall how to solve second order differential equations with constant coefficients and simple source functions. In...

    Keywords: bRLC circuitresonancebeatscurrentwireless telegraphyLC circuit

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    Box of Lessons: A Toolkit for Introducing Students to Biomolecular Structure and Function
    This is a poster describing a collection of open educational resources that were developed by faculty participating in the Molecular CaseNet Faculty Mentoring Network in Spring 2022. The collection...

    Keywords: bioinformaticsbiomolecular structureProtein Data Bankresources @ Molecular CaseNet

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    6-005-InsectColonySurvivalOpt-ModelingScenario
    We present a system of nonlinear differential equations to model the control of energy flow into producing workers or reproducers in an insect colony, using a set of given parameters and a number...

    Keywords: optimizationOptimal Control Theoryinsect colonyoptimal controlnatural resourcesPointryagin's Maximum Principlecontrol variable

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    2017-Adolfo_Rumbos-Differential Equations and modeling
    The study of any phenomenon in the physical or biological sciences, in which continuity and differentiability assumptions about the quantities in question can be made, invariably leads to a...

    Keywords: pendulumLotka Volterra equationsexistenceuniqueness

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    2009-Su-EtAl-Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS
    In the case of a multiple dose study where subjects experience different dosing times, a superposition principle can be used to recursively account for each additional dose.

    Keywords: SASsuperpositionpharmacokineticscompartmental modelsmultiple dose

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    2006-Juska-Gedminiene-Ivanec-Growth of Microbial Populations-Mathematical Modeling-Laboratory Exercises-Model-Based Data Analysis
    The aim is to teach the students to use a fresh approach to the problems they are familiar with, to come up with an articulate verbal model after a mental effort, to express it in rigorous...

    Keywords: population growth ratelogistic equationVerhulst equationgeneration timelag time

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    2007-Joseph_Myers-Brian_Winkel-Modeling_a_Mystery_Circuit_in_Mathematics_Class_Using_Differential_Equations_Laplace_Transforms_and_Transfer_Functions
    We discuss the introduction, student discovery, and teaching of a system of differential equations which model a circuit.

    Keywords: circuitLaplace transformtransfer functionmystery circuitvoltage frequencytwo loop circuit

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    3-042-CatapultLaunch-ModelingScenario
    We maximize the range of a projectile by backing up an incline in the opposite direction of the range to give some initial lift. Find the position on the hill from which to launch the projectile to...

    Keywords: projectile motioncatapultuphilllaunch angle

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    6-026-IsleRoyaleModeling-ModelingScenario
    The primary aim of this project is to draw a connection between differential equations and vector calculus, using population ecology modeling as a vehicle.

    Keywords: ecologyoptimizationpredator-preypopulationvector calculusLagrange multipliersleast squaresIslel Royale

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisgenetic basisPDBMolecular Case StudyMol*

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    Waking up Anna - Adaptations and Conversion to Mol*
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment. The adaptations addressed question clarity and reformatting to use Mol*.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABAMolCaseNetMol*MolStarProtein visualizationFlumazenil

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    Sequence Similarity: Introducing Biological Databases to Community College Biology Students
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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    Developing a phylogram from computational resources.
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsBLASTmultiple sequence alignmentsequence similarityneighbor-joining distance matrixCourseSourcephylogrampercent identity matrix

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    Why does Blood Flow Change? Investigating the Math of Blood Flow Dynamics
    This collection of activities explores the relationship between blood flow, pressure, and the factors of resistance through graphs and modeling direct and inverse variation.

    Keywords: quant biographingRatiosmathassessmentcollege algebraundergraduate educationphysiologyAnatomyhuman biologyvariationCardiovascular physiologyAnatomy & Physiologylab activityOpenStaxqbccmanipulate equationsUnderstanding fractionsChoosing modelsUnderstanding ratesEstimating answersUse elementary functionsCreate graphsInterpret graphsRates and ProportionsSolving Equations and Inequalities

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    Waking up Anna
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABA

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    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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    Introduction to Genome Browser: What is a Gene?
    In this module, we will use a web-based visualization tool called a Genome Browser to explore the structure of a eukaryotic gene, and obtain a basic understanding of how this information is...
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