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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Avida-ED
    Avida-ED is an award-winning educational application developed at Michigan State University for undergraduate biology courses to help students learn about evolution and scientific method.

    Keywords: simulationEvolutionbiologyscientific methodResources @ QUBES - Softwaredigitalhypotheses

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    Generating Biological Hypotheses in a "Course-based Undergraduate Research Experience"(CURE) Course
    Hypotheses are often incorrectly defined as educated guesses or if/then statements. Further confusion arises from the fact that not all disciplines define hypotheses similarly. The difficulty in...

    Keywords: scientific methodHPT axisNeural stem cells

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    Testing hypotheses about the role of wildfire in structuring avian communities
    This module assesses the role of wildfire in the eastern US and its impact on bird communities using NEON bird survey data from pre- and post- a major wildfire in the Great Smoky Mountains National...

    Keywords: data manipulationspecies richnessANOVAspecies diversitybirdswildfireBACI design

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    Bird Beak Adaptations
    Students will navigate through different stations experiencing simulations of adaptations, manipulations of 3D examples, and making connections to the standards to formulate hypotheses about...

    Keywords: EvolutionidigbiobirdsAnatomynatural history collectionsNatural Selection3D modelsAdaptations#NGSSVertebrate MorphologyoVert

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    Luria-Delbruck
    These two workbooks model the evolution of phage resistance in a bacterial population under two alternative hypotheses.

    Keywords: ExcelphageResources @ ESTEEMLuria-Delbruckresistance

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    Inquiry-based hypothesis testing using phylogenetic trees in MEGA
    A key learning objective in biology is applying bioinformatics tools to test a real-life question. These inquiry-based modules have students assemble and align data, and construct simple...

    Keywords: phylogeneticsbioinformaticsFASTANCBIBLASTmultiple sequence alignmentsequence similarityCourseSourceZika virusMEGAalcohol metabolism

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    Investigating the effects of urbanization on bird biodiversity: Testing three biodiversity hypotheses using citizen science data
    Students generate predictions and test three hypotheses about how biodiversity is affected by urbanization over time using citizen science generated bird count data and land use data from 13...

    Keywords: hypothesis testingBiodiversityurbanizationguided inquiryland useproductivity hypothesisecosystem stress hypothesisintermediate disturbance hypothesis

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    Attract or Defend? Secondary Compounds among tissues in two species of Lupine (Fabaceae)
    This plant-biology data analysis module compares concentrations of defensive alkaloid compounds among tissue types in two species of the flowering-plant Lupine (Fabaceae). Students practice with...
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    A Walk Through the Woods
    Data driven curriculum module from Dryad Digital Repository

    Keywords: ecologygraphingResources @ Dryadhypothesis testingdata visualizationbotanyclimate changeadaptationforestryDryadLabhypothesis formulationenvironmental pressureswood structure and function

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    Cold blood and wet skin in hot and dry secondary forests. How do amphibian traits determine persistence in secondary forests?
    Students will synthesize information from biological and physiological traits of amphibians and characteristics of secondary forests in the tropics to form hypotheses about persistence of...

    Keywords: life historyconservation biologyphysiological ecologyamphibianland use changeEctothermsecondary foresttrait-based ecology

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    BIOME Avida ED Report video - YouTube
    Avida-ED is a digital evolution software program that allows students to ask questions and test hypotheses related to evolutionary concepts. Our working group explored how to incorporate Avida-ED...
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    A CURE in traits and species distributions: Reproductive modes, range sizes, and natural history collections
    This course-based undergraduate research experience (CURE) focuses on developing hypotheses about how traits influence the range sizes of species. Topics with substantive content include symbioses,...

    Keywords: Evolutionbiostatisticsecologynatural history collectionsSymbiosisspecies distributionsherbariumplant functional traitsLichenReproductive biologyAppalachian mountains

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    Murder by HIV? Undergraduate edition
    Bioinformatics case study focusing on phylogenetic tree interpretation, published in the National Center for Case Study Teaching in Science

    Keywords: case studyResources @ NSF - NCCSTSbioinformaticsNIBLSEHIVnucleotide sequencingphylogenetic treeviral life cyclesmutation ratesreverse transcriptase sequences

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    Biodiversity, Big Data, and the Fossil Record
    In this lab, we will be making and testing hypotheses about how the biodiversity of groups of organisms may vary through time.

    Keywords: digital resourcesnatural history museumspaleobiology

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    Comparing Primary and Secondary Forest in a Preserve in Plano Texas: A Forest Ecology Course-based Undergraduate Research Experience (CURE) for Non-Majors and Lower-Level Majors
    An activity that can be conducted as an online or field exercise in which students develop and test their hypotheses about how forest stand characteristics differ between two forest types.

    Keywords: forest ecologyecologycourse-based undergraduate research experienceUsing Excel

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    Staying Alive: Extinction Risk: Introduction to Extinction and Extinction Bias
    Data driven curriculum module from Dryad Digital Repository

    Keywords: ecologydata analysisconservationgraphingResources @ Dryadextinctionmacroevolution

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    The nose knows: How tri-trophic interactions and natural history shape bird foraging behavior. An introduction to statistical analysis in animal behavior research
    Students investigate the role of olfaction and infochemicals on bird foraging behavior through two different quantitative activities where they generate hypotheses, create figures, conduct data...

    Keywords: Resources @ ESA - TIEEforagingfmnanimal behaviorbehavioral ecologyDIGtrophic cascades

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    Dendroclimatology
    Dendroclimatologists can reconstruct climate records further into the past than written records, by examining tree rings. Students "reverse-engineer" this process by considering growth rates of a...

    Keywords: linear regressiongraphingdata visualizationstandardizationclimatetree ringsdendrochronology

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    5-030-LinNonHomoSystemSol-TechniqueNarrative
    We offer strategies for solving linear systems of nonhomogeneous differential equations using a conjectured solution strategy for a system of constant coefficient, linear, n

    Keywords: strategiesdiscovery learningeigenvectorseigenvalue

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    Diseasebots HEXBUG Lab
    This module explores the effects of host density on contact rates and transmission of pathogens using a hands-on experiment with HEXBUG robots.
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